CAS: 1719-71-7; Tetrazolium Violet

相似化合物

298-96-4 1096-80-6 135788-08-8

专利信息

专利号:US-9575067-B2
优先权日:2007-05-23
标 题 :Polymeric carriers for immunohistochemistry and in situ hybridization
发明人：KOSMEDER II JERRY W; KERNAG CASEY A; JOHNSON DONALD; BIENIARZ CHRISTOPHER
权利人:VENTANA MED SYST INC
摘要:Certain disclosed embodiments of the present invention concern the synthesis, derivatization, conjugation to immunoglobulins and signal amplification based on discrete, relatively short polymers having plural reactive functional groups that react with plural molecules of interest. Reactive functional groups, such as hydrazides, may be derivatized with a variety of detectable labels, particularly haptens. The remaining reactive functional groups may be conjugated directly to a specific binding molecule, such as to the oxidized carbohydrate of the Fc region of the antibody. Disclosed conjugates display large signal amplification as compared to those based on molecules derivatized with single haptens, and are useful for assay methods, particularly multiplexed assays.

专利号:US-2012070862-A1
优先权日:2009-12-31
标题 :Methods for producing uniquely distinct nucleic acid tags
发明人：ALEXANDER NELSON; STANISLAW STACEY
权利人:ALEXANDER NELSON; STANISLAW STACEY; VENTANA MED SYST INC
摘要:Disclosed herein are uniquely distinct nucleic acid tags and methods for their use and production. The disclosed tags do not hybridize to a genome of interest and thus can be used as labels without generating background signal associated with unintended hybridization. In one example, tag sequences are derived from a genome divergent to the genome of interest. The divergent genome provides a vast library of potential tag sequences. These potential tag sequences can be screened using a bioinformatics-based approach against the genome of interest. These potentially distinct sequences can then be synthesized and tested empirically against the genome of interest to identify those sequences that are uniquely distinct. The tags can then be produced, for example by oligonucleotide synthesis techniques.

专利号:US-5635484-A
优先权日:1982-09-17
标题 :Propionibacteria peptide microcin
发明人：AYRES JAMES W; SANDINE WILLIAM E; WEBER GEORGE H
权利人:OREGON STATE
摘要:A peptide, produced by propionibacteria, has a molecular weight of between 300 and 1200 daltons and is inhibitory to gram-negative bacteria. The peptide can be produced by purification of a propionibacteria metabolite mixture, by chemical synthesis, or by a host transformed with a recombinant vector, and is useful in preventing and treating bacterial infections.