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790667-49-1 790667-43-5 13729-77-6欧盟法规
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CAS号71322-99-1 2-甲基-4-哌啶酮 | CAS号24424-99-5 二碳酸二叔丁酯 | CAS号126503-08-0 1,4-Dioxa-8-aza... | CAS号849928-34-3 1-CBZ-2-甲基-4-哌啶酮 | CAS号620-08-6 4-甲氧基吡啶 | CAS号865-47-4 叔丁醇钾 | CAS号676-58-4 甲基氯化镁 | CAS号1382774-58-4 2-methyl-4-pipe... | CAS号790667-43-5 (R)-2-甲基-4-氧代哌啶... | CAS号790667-49-1 1-N-b°C-2(s)-甲基... | CAS号790667-44-6 2-甲基-2-丙基(2R,4R... | CAS号790668-06-3 (2R,4S)-4-羟基-2-... | CAS号790667-91-3 (2S,4R)-4-羟基-2-... | CAS号790667-99-1 (2S,4S)-4-羟基-2-...N-Boc-7-Methyl-1,4-Dioxa-8-Azaspiro<4.5>Decane置于对甲苯磺酸体系中,用 丙酮 用作溶剂,以48%的收率获得1-叔丁氧羰基-2-甲基-哌啶酮
参考文献:Ep1375482
标题:Ep1375482
海关参考信息
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2905143000-叔丁醇
2912110000-甲醛
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专利信息
专利号:WO-0146142-A1
优先权日:1999-12-20
标题:A process for the regioselective synthesis of 2,2-dialkyl-4-substituted piperidines
发明人:HEATH PERRY CLARK
权利人:LILLY CO ELI; HEATH PERRY CLARK
摘要:The present invention provides a process for preparing a compound of formula (I): wherein R?1 and R2¿ each independently represent C¿1?-C4 alkyl; and X represents an alkyl, alkenyl, cycloalkyl, aryl, substituted aryl, heterocycle, or substituted heterocycle, comprising treating a compound of formula (II): wherein Q represents Cl or Br, with a suitable base followed by addition of a suitable Lewis acid and addition of a compound of formula R?-M+¿ wherein M+ is a suitable cation.
专利号:US-2024400552-A1
优先权日:2016-11-11
标题 :Heterocyclic modulators of lipid synthesis
发明人:BUCKLEY DOUGLAS I; DUKE GREGORY; WAGMAN ALLAN S; EVANCHIK MARC; MCDOWELL ROBERT S
权利人:SAGIMET BIOSCIENCES INC
摘要:Compounds that are fatty acid synthesis modulators are provided. The compounds may be used to treat disorders characterized by dysregulation of the fatty acid synthase function by modulating the function and/or the fatty acid synthase pathway. Methods are provided for treating such disorders including viral infections, such as hepatitis C infection, cancer and metabolic disorders, such as non-alcoholic steatohepatitis (NASH).
专利号:US-11622968-B2
优先权日:2011-03-08
标 题:Heterocyclic modulators of lipid synthesis
发明人:BUCKLEY DOUGLAS; DUKE GREGORY; WAGMAN ALLAN S; EVANCHIK MARC; MCDOWELL ROBERT S
权利人:SAGIMET BIOSCIENCES INC
摘要:Compounds that are fatty acid synthesis modulators are provided. The compounds may be used to treat disorders characterized by disregulation of the fatty acid synthase function by modulating the function and/or the fatty acid synthase pathway. Methods are provided for treating such disorders including viral infections, such as hepatitis C infection, cancer and metabolic disorders, such as non-alcoholic steatohepatitis (NASH).
专利号:US-11034690-B2
优先权日:2016-11-11
标 题:Heterocyclic modulators of lipid synthesis
发明人:BUCKLEY DOUGLAS I; DUKE GREGORY; WAGMAN ALLAN S; EVANCHIK MARC; MCDOWELL ROBERT S
权利人:SAGIMET BIOSCIENCES INC; SAGINIET BIOSCIENCES INC
摘要:Compounds that are fatty acid synthesis modulators are provided. The compounds may be used to treat disorders characterized by disregulation of the fatty acid synthase function by modulating the function and/or the fatty acid synthase pathway. Methods are provided for treating such disorders including viral infections, such as hepatitis C infection, cancer and metabolic disorders, such as non-alcoholic steatohepatitis (NASH).
专利号:US-9809591-B2
优先权日:2011-03-08
标题 :Heterocyclic modulators of lipid synthesis
发明人:OSLOB JOHAN D; MCDOWELL ROBERT S; JOHNSON RUSSELL; YANG HANBIAO; EVANCHIK MARC; ZAHARIA CRISTIANA A; CAI HAIYING; HU LILY W
权利人:3-V BIOSCIENCES INC
摘要:Compounds that are fatty acid synthesis modulators are provided. The compounds may be used to treat disorders characterized by disregulation of the fatty acid synthase function by modulating the function and/or the fatty acid synthase pathway. Methods are provided for treating such disorders including viral infections, such as hepatitis C infection, cancer and metabolic disorders.
专利号:EP-1242377-A1
优先权日:1999-12-20
标题:A process for the regioselective synthesis of 2,2-dialkyl-4-substituted piperidines