CAS: 696-42-4; 5-Fluoronicotinonitrile

相似化合物

402-66-4 39891-04-8 407-21-6

上下游产品

zinc(II) cyanide 3-bromo-5-fluoropyridine 5-bromopyridine-3-carbonitrile 5-fluoro-3-pyridinecarbonyl chloride 5-(3-iodo-1H-pyrazol-1-yl)nicotinonitrile ((5-fluoropyridin-3-yl)methyl)amine

5-溴烟腈置于potassium Fluoride,氟化银,{2,6-Bis[2,6-Diisopropyl-4-(Benzhydryl)Phenyl]Phenyl}Dicyclohexylphosphine(2'-Methylaminobiphenyl-2-Yl-η2-C,N)Palladium(II) Toluenesulfonate体系中,用 2-甲基四氢呋喃 作为反应溶剂,以88 %的收率获得产物5-氟-3-氰基吡啶
参考文献:芳甲基联芳基的膦配体及其过渡金属络合物
标题:芳甲基联芳基的膦配体及其过渡金属络合物
摘要:本发明提供带芳甲基联芳基膦配体及其制备方法;本发明还提供芳甲基联芳基膦配体配位的钯,镍络合物及其在偶联反应和烯烃聚合反应中的用途.

专利信息

专利号:US-2025129021-A1
优先权日:2023-09-19
标 题:Small molecule protein synthesis modulators
发明人：GYGI DAVID; BAHMANYAR SOGOLE SAMI; HAMANN LAWRENCE
权利人:INTERDICT BIO INC
摘要:The present disclosure provides compounds of the formulae herein (e.g., Formula (I), Formula (V)), and pharmaceutically acceptable salts thereof, which are useful for modulating protein synthesis (e.g., modulating synthesis of BCL-2, MYC, CCND1, MCL-1, ALK, KRAS-G12D). The present disclosure also provides pharmaceutical compositions and kits comprising the compounds, or pharmaceutically acceptable salts thereof, and methods of treating or preventing diseases or disorders (e.g., diseases or disorders associated with BCL-2, MYC, CCND1, MCL-1, ALK, KRAS-G12D) by administering to a subject in need thereof the compounds, or pharmaceutically acceptable salts thereof, or pharmaceutical compositions thereof.

专利号:NZ-254628-A
优先权日:1992-08-20
标 题:Synthesis of 2,6-dichloro-5-fluoronicotinic acid or -nicotinoyl chloride

专利号:SK-23295-A3
优先权日:1992-08-20
标 题 :Process for the synthesis of 2,6-dichloro-5-fluoronicotinic acid and 2,6-dichloro-5-fluoronicotinoyl chloride