专利号:US-2016194279-A1 优先权日:2012-12-09 标 题 :One pot process for the conversion of aroyl chlorides to acyl thioureas 发明人:CHEPURI VENKATA RAMANA; BEERAN SENTHILKUMAR 权利人:COUNCIL SCIENT IND RES 摘要:The present invention disclose an improved one pot process for synthesis of acyl thioureas of formula (I), with yield greater than 80%, from aroyl chlorides of formula (I) wherein, R′ is an aryl or a heteroarylene group substituted with one or more groups selected from hydrogen, alkyl, alkylene, alkynyl, alkoxy, alkenyloxy, halo, hydroxyl, nitro, amino, carboxyl, ester, halogenated hydrocarbon or an aryl or heteroaryl; R″ and R′″ are selected independently from hydrogen, alkyl, alkylene, alkynyl, alkoxy, alkenyloxy, halo, hydroxyl, nitro, amino or halogenated hydrocarbon.
专利号:US-6375703-B1 优先权日:2000-10-17 标 题:Method of synthesizing nickel fibers and the nickel fibers so prepared 发明人:CHOU KAN-SEN; REN CHIANG-YUH; LO CHIEH-TSUNG 权利人:NAT SCIENCE COUNCIL 摘要:The present invention discloses s novel synthesis method of nickel fibers. The method of the present invention involves reducing nickel ions in an aqueous solution with a reducing agent in the presence of a base, a pH buffer, and a magnetic field or a surfactant at a temperature of 80-100° C. for a period of time, wherein a pH value of the aqueous solution is not less than 11.0 during the period of time, so that nickel fibers are formed in the aqueous solution. The nickel fibers synthesized in the present invention have a diameter ranging from sub-micron to microns, and a length up to centimeters.
专利号:US-7588757-B2 优先权日:2001-03-14 标题 :Methods of treating Parkinson's disease using recombinant adeno-associated virus virions 发明人:OZAWA KEIYA; FUJIMOTO KEN-ICHI; MURAMATSU SHIN-ICHI; IKEGUCHI KUNIHIKO; NAKANO IMAHARU 权利人:GENZYME CORP 摘要:Methods for treating Parkinson's disease (PD) are provided. Recombinant adeno-associated virus (rAAV) virions are used to deliver genes encoding dopamine-synthesizing enzymes to the central nervous system of a primate. Once delivered, the genes are expressed, which then results in dopamine synthesis and amelioration in the clinical signs and symptoms of PD. The methods of the present invention can be used to deliver the three central dopamine synthesizing enzymes: tyrosine hydroxylase, aromatic L-amino acid decarboxylase, and guanosine triphosphate cyclohydrolase I thereby enhancing dopamine biosynthesis and providing for enhanced therapeutic efficacy.
专利号:CN-103183330-B 优先权日:2013-04-02 标 题:Controllable synthesis of nitrogen and phosphorus co-doped graphitized carbon spheres with hollow structure
专利号:CN-103193223-A 优先权日:2013-04-02 标题 :Controllable synthesis of graphitized carbon spheres with hollow structures
专利号:CN-103183330-A 优先权日:2013-04-02 标题 :Controllable synthesis of nitrogen and phosphorus co-doped graphitized carbon spheres with hollow structure
摘要:Food & Drug Research Laboratories, Inc., Papers., 8005A(1984) 摘要:USEPA/Office of Water; Federal-State Toxicology and Risk Analysis Committee (FSTRAC). Summary of State and Federal Drinking Water Standards and Guidelines (11/93) To Present 摘要:Mackison, F. W., R. S. Stricoff, and L. J. Partridge, Jr. (eds.). NIOSH/OSHA - Occupational Health Guidelines for Chemical Hazards. DHHS(NIOSH) Publication No. 81-123 (3 VOLS). Washington, DC: U.S. Government Printing Office, Jan. 1981., p. 3 摘要:Sax, N.I. and R.J. Lewis, Sr. (eds.). Hawley's Condensed Chemical Dictionary. 11th ed. New York: Van Nostrand Reinhold Co., 1987., p. 819 摘要:L41: ATSDR - Agency for Toxic Substances and Disease Registry (2005). Toxicological profile for nickel. U.S. Public Health Service in collaboration with U.S. Environmental Protection Agency (EPA). http://www.atsdr.cdc.gov/toxprofiles/tp15.html