CAS: 17745-04-9; 2-(Imidazo[1,2-A]Pyridin-3-yl)Acetic Acid

相似化合物

101820-69-3 1244029-51-3 19741-30-1

上下游产品

2-aminopyridine ethyl 4-oxo-2-butenoate 2-(imidazo[1,2-a]pyridin-3-yl)acetonitrile imidazo[1,2-α]pyridin-3-yl-acetic acid ethyl ester

3-溴咪唑[1,2-A]嘧啶置于copper(I) Oxide,Potassium Tert-Butylate,Copper(I) Bromide,Sodium Hydroxide体系中,用 1,4-二氧六环,乙醇,水,乙腈 用作溶剂,化学反应 9.0H,反应生成咪唑并[1,2-A]吡啶-3-乙酸
参考文献:一种米诺磷酸中间体的制备方法
标题:一种米诺磷酸中间体的制备方法
摘要:本发明涉及一种米诺磷酸中间体的制备方法,该方法以化合物i‑1原料,在催化剂溴化亚铜和缚酸剂叔丁醇钾作用下与化合物i‑2反应制得中间体i‑3,中间体i‑3经氢氧化钠水解得到中间体1‑4,中间体1‑4经氧化亚铜脱羧基后制得中间体i,即为所述的米诺磷酸中间体.与现有技术相比,本发明具有原料易得,工艺简单,操作方便,反应收率高(三步收率高达80%)和利于工业化生产的优势.

专利信息

专利号:CN-104693241-A
优先权日:2015-03-02
标 题 :'One-pot method' synthesis of minodronic acid intermediate and method for preparing minodronic acid

专利号:CN-102093352-B
优先权日:2011-01-30
标 题:A key intermediate of minodronic acid and its synthesis method and the method for synthesizing minodronic acid from the intermediate

专利号:CN-102093352-A
优先权日:2011-01-30
标 题:A key intermediate of minodronic acid and its synthesis method and the method for synthesizing minodronic acid from the intermediate

专利号:CN-111253395-A
优先权日:2020-02-17
标 题 :Synthesis method of naphtho[1',2':4,5]imidazo[1,2-a]pyridine-5,6-dione compound

专利号:CN-111253395-B
优先权日:2020-02-17
标 题:Synthesis method of naphtho [1',2':4,5] imidazo [1,2-a ] pyridine-5, 6-diketone compound

专利号:CN-112390823-B
优先权日:2019-08-19
标 题 :A kind of synthesis method of minodronic acid