CAS: 56341-37-8; 6-Chlorooxindole

上下游产品

CAS号6341-92-0 6-氯靛红 | CAS号147124-32-1 2-(4-氯-2-硝基苯基)丙二酸二甲酯 | CAS号37777-71-2 2-(4-氯-2-硝基苯基)乙酸 | CAS号147124-37-6 2-(4-氯-2-硝基苯基)乙酸甲酯 | CAS号89-61-2 2,5-二氯硝基苯 | CAS号10565-16-9 (4-Chlor-2-nitr... | CAS号879-32-3 6-Chlor-3-hydra... | CAS号108-42-9 间氯苯胺 | CAS号17122-55-3 N-(3-氯-苯基)-2-[(... | CAS号295800-01-0 6-pyridin-3-yl-... | CAS号6341-92-0 6-氯靛红 | CAS号122883-93-6 盐酸齐拉西酮 | CAS号118289-55-7 6-氯-5-(2-氯乙基)羟吲哚 | CAS号884305-06-0 佐帕司通杂质 | CAS号118307-04-3 5-氯乙酰-6-氯-1,3-二... | CAS号177985-31-8 2-氨基-4-氯苯乙酸 | CAS号651747-72-7 1-acetyl-6-chlo... | CAS号69111-62-2 2,6-dichloro-1H... | CAS号897365-76-3 3-(3-氯-2-氟亚苄基)-...

2,5-二氯硝基苯置于potassium Tert-Butylate,Lithium Chloride体系中,用 二甲基亚砜,N,N-二甲基甲酰胺 作为反应溶剂,化学反应 6.17H,反应生成 6-氯氧化吲哚
参考文献:十字花科植物抗毒素brassilexin,Sinalexin,Wasalexins和类似物的简明合成:扩大vilsmeier甲酰化的范围
标题:十字花科植物抗毒素brassilexin,Sinalexin,Wasalexins和类似物的简明合成:扩大vilsmeier甲酰化的范围
摘要:通过将vilsmeier甲酰化应用到二氢吲哚-2-硫酮上,然后进行新的氨水后处理程序,证明了植物抗毒素黄铜素,芥辣素和类似物的有效合成.类似地,描述了使用顺式吲哚-2-酮的甲酰化-氨化非常精确的两锅合成植物抗毒素wasalexins.引人注目的是,这种新颖的氨水后处理允许顺序进行一锅甲酰化氨化反应,从而大大扩大了吲哚啉-2-硫酮和吲哚-2-酮的维尔斯迈尔甲酰化作用的范围.据报道,甲酰化-胺化反应的检查和条件的优化,以及几种黄铜蛋白类似物的合成和抗真菌活性.
DOI:10.1021/jo0479866

专利信息

专利号:WO-9948868-A9
优先权日:1998-03-26
标 题 :Heterocyclic classes of compounds for the modulating tyrosine protein kinase
发明人：FONG ANNIE; HANNAH ALISON; HARRIS G DAVIS; HIRTH PETER; HUBBARD STEVEN R; LANGECKER PETER; LIANG CONGXIN; MCMAHON GERALD; MOHAMMADI MOOSA; SCHLESSINGER JOSEPH; SHAWVER LAURA K; SUN LI; TANG PENG C; ULLRICH AXEL
权利人:SUGEN INC; UNIV NEW YORK; MAX PLANCK INST FUR BIOCHEMIE; FONG ANNIE; HANNAH ALISON; HARRIS G DAVIS; HIRTH PETER; HUBBARD STEVEN R; LANGECKER PETER; LIANG CONGXIN; MCMAHON GERALD; MOHAMMADI MOOSA; SCHLESSINGER JOSEPH; SHAWVER LAURA K; SUN LI; TANG PENG C; ULLRICH AXEL
摘要:The invention relates to certain indolinone-based and pyrazolylamide-based compounds, their method of synthesis, and combinatorial libraries consisting of the compounds. The invention also relates to methods of modulating the function of protein kinases using these compounds and methods of treating diseases by modulating the function of protein kinases and related signal transduction pathways.

专利号:US-2004067531-A1
优先权日:1997-08-20
标 题:Methods of modulating protein tyrosine kinase function with substituted indolinone compounds
发明人：TANG PENG CHO; SUN LI; TRAN NGOC MY; NGUYEN ANH THI; NEMATALLA ASAAD
权利人:SUGEN INC
摘要:The invention relates to certain indolinone compounds, their method of synthesis, and a combinatorial library consisting of the indolinone compounds. The invention also relates to methods of modulating the function of protein tyrosine kinases using indolinone compounds and methods of treating diseases by modulating the function of protein tyrosine kinases and related signal transduction pathways.

专利号:US-6514981-B1
优先权日:1998-04-02
标题:Methods of modulating tyrosine protein kinase function with indolinone compounds
发明人：TANG PENG CHO; SUN LI
权利人:SUGEN INC
摘要:The invention relates to certain indolinone compounds, their method of synthesis, and a combinatorial library consisting of the indolinone compounds. The invention also relates to methods of modulating the function of protein tyrosine kinases using indolinone compounds and methods of treating diseases by modulating the function of protein tyrosine kinases and related signal transduction pathways.

专利号:CN-1635892-A
优先权日:2002-02-20
标题:Controlled synthesis of ziprasidone and compositions thereof

专利号:EP-1476162-A1
优先权日:2002-02-20
标题:Controlled synthesis of ziprasidone and compositions thereof

专利号:JP-2005525347-A
优先权日:2002-02-20
标 题:Controlled synthesis of ziprasidone and its compositions