CAS: 18968-05-3; (2S,3S,4R,5R,6R)-6-(Acetoxymethyl)-3-Hydroxytetrahydro-2H-Pyran-2,4,5-Triyl Triacetate

相似化合物

22415-91-4 97-30-3 83-87-4

上下游产品

O3,O4,O6-triacetyl-β-D-mannopyranosyl chlorideO3,O4,O6-triacetyl-β-D-mannopyranosyl chloride acetobromomannose D-Mannose acetic anhydride 1,3,4,6-tetra-O-acetyl-2-O-trifluoromethanesulfonyl-β-D-mannopyranose 2-O-(6-O-benzyl-2,3,4-trideoxy-α-D-glycero-hex-2-enopyranosyl)-1,3,4,6-tetra-O-acetyl-β-D-mannopyranose 2-O-(6-O-benzyl-2,3,4-trideoxy-α-L-glycero-hex-2-enopyranosyl)-1,3,4,6-tetra-O-acetyl-β-D-mannopyranose 1,3,4,6-Tetra-O-acetyl-2-O-(diphenoxyphosphoryl)-β-D-mannopyranose

D-Mannose Ethyl Orthoacetate置于盐酸体系中,用 水,丙酮 用作溶剂,化学反应 0.17H,以26%的收率获得1,3,4,6-四-氧-乙酰-β-D-吡啶甘露糖
参考文献:一种方便,有效的合成方法,用于单,双和三-O-甘露糖基化的fmoc氨基酸
标题:一种方便,有效的合成方法,用于单,双和三-O-甘露糖基化的fmoc氨基酸
摘要:描述了单-,二-和三-O-甘露糖基化的fmoc-Ser和thr的便捷高效合成方法.较短的合成路线和较高的总产率突出了这种统一方法的合成效用.
Doi:10.1016/j.Tetlet.2013.02.060

专利信息

专利号:US-9895454-B2
优先权日:2014-07-03
标题:Metal oxide catalyzed radiofluorination
发明人：SERGEEV MAXIM; MORGIA FEDERICA; VAN DAM ROBERT MICHAEL; LAZARI MARK
权利人:UNIV CALIFORNIA
摘要:Inter alia, the first titania-catalyzed [ 18 F]-radiofluorination in highly aqueous medium is provided. In embodiments, the method utilizes titanium dioxide, 1:1 acetonitrile-thexyl alcohol solvent mixture and tetrabutylammonium bicarbonate as a base. Radiolabeling may be directly performed with aqueous [ 18 F]fluoride without the need for drying/azeotroping step, which reduces radiosynthesis time while keeping high fluoride conversion. The general applicability of the synthetic strategy to the synthesis of the wide range of PET probes from tosylated precursors is demonstrated.

专利号:RU-2165266-C1
优先权日:2000-06-28
标题 :Method of synthesis of [2-18f]-2-deoxyglucose

专利号:US-9073802-B2
优先权日:2010-02-12
标题 :Method for producing 18F-labeled compound and high molecular compound to be used in the method
发明人：TAKAHASHI TAKASHI; TANAKA HIROSHI; NAKADA TSUTOMU
权利人:TAKAHASHI TAKASHI; TANAKA HIROSHI; NAKADA TSUTOMU; TOKYO INST TECH; UNIV NIIGATA
摘要:The present invention aims at solving the problems of conventional methods for producing an 18 F-labeled compound, that is, the problem of purification of a compound in a liquid phase synthesis method and the problem of an insufficient yield due to the reduction of reactivity in a solid phase synthesis method. There is provided a method for producing an 18 F-labeled compound including: allowing a high molecular compound containing a residue of a precursor compound to be labeled and a residue of a phase transfer catalyst in the molecule thereof to react with 18 F − ; and removing the 18 F-labeled compound from the high molecular compound.