CAS: 167392-57-6; (R)-Ethyl Piperidine-3-Carboxylate (2S,3S)-2,3-Dihydroxysuccinate

相似化合物

1227911-35-4 2070009-48-0 37675-19-7

专利信息

专利号:US-7816375-B2
优先权日:2000-09-11
标 题 :Ligands for monoamine receptors and transporters, and methods of use thereof
发明人：AQUILA BRIAN M; BANNISTER THOMAS D; CUNY GREGORY D; HAUSKE JAMES R; HOLLAND JOANNE M; PERSONS PAUL E; RADEKE HEIKE; WANG FENGJIANG; SHAO LIMING
权利人:SEPRACOR INC
摘要:One aspect of the present invention relates to heterocyclic compounds. A second aspect of the present invention relates to the use of the heterocyclic compounds as ligands for various mammalian cellular receptors, including dopamine, serotonin, or norepinephrine transporters. The compounds of the present invention will find use in the treatment of numerous ailments, conditions and diseases which afflict mammals, including but not limited to addiction, anxiety, depression, sexual dysfunction, hypertension, migraine, Alzheimer's disease, obesity, emesis, psychosis, schizophrenia, Parkinson's disease, inflammatory pain, neuropathic pain, Lesche-Nyhane disease, Wilson's disease, and Tourette's syndrome. An additional aspect of the present invention relates to the synthesis of combinatorial libraries of the heterocyclic compounds, and the screening of those libraries for biological activity, e.g., in assays based on dopamine transporters.

专利号:US-2002177721-A1
优先权日:2000-12-04
标题 :Methods for the stereoselective synthesis of substituted piperidines

专利号:US-6703508-B2
优先权日:2000-12-04
标 题:Methods for the stereoselective synthesis of substituted piperidines

专利号:US-7005524-B2
优先权日:2000-12-04
标 题 :Methods for the stereoselective synthesis of substituted piperidines

专利号:RU-2178790-C2
优先权日:1995-09-19
标题:Derivatives of dibenzo[d,g][1,3]dioxocine and dibenzo[d,g]- [1,3,6]dioxazocine, method of their synthesis, pharmaceutical composition based on thereof and method of treatment of neurogenic inflammation, neuropathy and rheumatic arthritis