CAS: 42508-74-7; (4-Methylpyridin-2-yl)Methanol

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53547-60-7 4021-08-3 13509-13-2

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CAS号55485-91-1 (4-methylpyridi... | CAS号108-47-4 2,4-二甲基吡啶 | CAS号1122-45-8 2,4-二甲基吡啶 N-氧化物 | CAS号1003-67-4 4-甲基吡啶-N-氧化物 | CAS号420-37-1 三甲基氧鎓四氟硼酸 | CAS号13509-13-2 4-甲基吡啶-2-甲酸甲酯 | CAS号1620-76-4 2-氰基-4-甲基吡啶 | CAS号4021-08-3 4-甲基吡啶-2-甲酸 | CAS号108-24-7 乙酸酐 | CAS号38198-16-2 2-氯-4-甲基吡啶 | CAS号53547-60-7 4-甲基-2-吡啶醛 | CAS号71670-71-8 2-氯甲基-4-甲基吡啶盐酸盐 | CAS号442910-29-4 2-(溴甲基)-4-甲基吡啶

4-甲基吡啶氧化物置于sodium Tetrahydroborate,氯化亚砜,水,Potassium Hydroxide,二甲氨基甲酰氯体系中,用 甲醇,二氯甲烷 作为反应溶剂,化学反应 53.5H,反应生成 (4-甲基-吡啶-2-基)-甲醇
参考文献:Fe(pytacn)-过氧化氢催化烯烃的顺-二羟基化
标题:Fe(pytacn)-过氧化氢催化烯烃的顺-二羟基化
摘要:通式为[fe(II)(r,Y,X Pytacn)(cf 3 So 3)2]的铁络合物家族,其中r,Y,X Pytacn = 1‐ [2'‐(4‐y‐6-[x-吡啶基)甲基]-4,7-二烷基-1,4,7-三氮杂环壬烷,X和y分别表示吡啶的4和6位上的基团,R表示在n-处的烷基取代基三氮杂双环壬烷环的4和n-7被证明是使用过氧化氢作为氧化剂进行有效且选择性的烯烃氧化(环氧化和顺式-二羟基化)的催化剂.络合物[fe(II)(me,Me,H Pytacn)(cf 3 So 3)2](7)被认为是该家族中最有效和选择性最强的顺式-二羟基化催化剂.7的高活性使烯烃的氧化在室温下以及在不大量使用烯烃而仅是限制性试剂的条件下迅速进行(30分钟).在3%(摩尔)的存在下7,2当量.H2O 2作为氧化剂,当量为15当量.在乙腈溶液中,水被烯烃顺式-二羟基化,其收率可能对于合成目的是令人感兴趣的.竞
DOI:10.1002/adsc.201200938

专利信息

专利号:US-5521179-A
优先权日:1991-04-18
标题 :Heterocyclic amides
发明人：BERNSTEIN PETER R; SHAW ANDREW; THOMAS ROYSTON M; WARNER PETER; WOLANIN DONALD J
权利人:ZENECA LTD
摘要:The present invention relates to certain novel heterocyclic amides which are 1-pyridylacetamide compounds of formula I, set out herein, which are inhibitors of human leukocyte elastase (HLE), also known as human neutrophil elastase (HNE), making them useful whenever such inhibition is desired, such as for research tools in pharmacological, diagnostic and related studies and in the treatment of diseases in mammals in which HLE is implicated. The invention also includes intermediates useful in the synthesis of these heterocyclic amides, processes for preparing the heterocyclic amides, pharmaceutical compositions containing such heterocyclic amides and methods for their use.

专利号:CN-104610138-A
优先权日:2015-01-09
标题 :Synthesis of ethylenediaminetetraacetic acid probes for protein paramagnetic labeling

专利号:US-5084458-A
优先权日:1987-05-14
标 题 :Substituted 2-acylpyridine-β-(N)-hetaryl-hydrazones and medicaments containing the same
发明人：SCHAPER KLAUS-JUERGEN; SEYDEL JOACHIM K
权利人:SCHAPER KLAUS JUERGEN; SEYDEL JOACHIM K
摘要:PCT No. PCT/DE88/00289 Sec. 371 Date Mar. 7, 1989 Sec. 102(e) Date Mar. 7, 1989 PCT Filed May 14, 1988 PCT Pub. No. WO88/08842 PCT Pub. Date Nov. 17, 1988.Substituted 2-acylpyridine- alpha -(N)-hetarylhydrazones are described, which are suitable as active substances for the treatment of antimicrobial and in particular antimycobacterial diseases, as well as active substances for the treatment of malaria or malignant tumours. The compounds have a marked synergistic activity combined with inhibitors of folate synthase, dihydrofolic acid reductase, DNA-synthesis and RNA-synthesis.