CAS: 4136-97-4; Methyl 4-Amino-2-Hydroxybenzoate

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CAS号619-19-2 4-硝基水杨酸 | CAS号67-56-1 甲醇 | CAS号65-49-6 对氨基水杨酸 | CAS号13684-28-1 2-羟基-4-硝基苯甲酸甲酯 | CAS号7664-93-9 硫酸 | CAS号1336-21-6 氨水 | CAS号77-78-1 硫酸二甲酯 | CAS号144-55-8 碳酸氢钠 | CAS号7440-44-0 活性炭 | CAS号186581-53-3 重氮甲烷 | CAS号27492-84-8 2-甲氧基-4-氨基苯甲酸甲酯 | CAS号106868-33-1 methyl 2-methox... | CAS号4235-43-2 4-乙酰氨基-5-氯-2-乙氧... | CAS号35290-97-2 4-氨基-5-溴-2-甲氧基苯甲酸 | CAS号4093-29-2 胃复安甲基物 | CAS号4093-31-6 5-氯-4-乙酰氨基-2-甲氧... | CAS号4093-34-9 2-甲氧基-4-乙酰胺基-5-... | CAS号4093-28-1 4-乙酰氨基水杨酸甲酯 | CAS号179872-39-0 4-amino-5-chlor... | CAS号27559-59-7 4-(二甲氨基)-2-羟基苯甲酸甲酯

4-氨基水杨酸置于甲醇,硫酸体系中,用95.1%的收率获得产物2-羟基-4-氨基苯甲酸甲酯
参考文献:5Ht 4激动剂的关键苯并吡喃中间体的合成途径的研究
标题:5Ht 4激动剂的关键苯并吡喃中间体的合成途径的研究
摘要:葛兰素史克(glaxosmithkline)的5Ht 4受体激动剂1的供应途径以关键的苯并吡喃片段2的构建为中心.我们通过一系列断开连接来描述为该组件定义最终制造路线的尝试.构造苯并吡喃骨架的系统方法集中在适当前体的环化策略和关键步骤性能的评估上.
DOI:10.1021/op900188V

专利信息

专利号:US-7737166-B2
优先权日:2005-08-17
标 题:Antifungal bicyclic hetero ring compounds
发明人：KAWAKAMI KATSUHIRO; KANAI KAZUO; HORIUCHI TAKAO; TAKESHITA HIROSHI; KOBAYASHI SYOZO; SUGIMOTO YUICHI; ACHIWA ISSEI; KUROYANAGI JUNICHI
权利人:DAIICHI SANKYO CO LTD
摘要:A 1,6-β-glucan synthetase inhibitor is provided, having potent growth inhibition and having excellent safety. A compound is provided, capable of expressing in a wide spectral range and specifically or selectively, an antifungal effect based on its functional mechanism of 1,6-β-glucan synthesis inhibition. Also provided is a drug, a salt or hydrate thereof, especially an antifungal that contains the compound. Concretely, provided is a compound of the following formula (I), its salt or hydrate, and a drug or antifungal containing, as the active ingredient, the compound, its salt or hydrate:

专利号:US-9700543-B2
优先权日:2011-05-31
标题 :GLP-1 receptor stabilizers and modulators
发明人：BOEHM MARCUS F; MARTINBOROUGH ESTHER; MOORJANI MANISHA; TAMIYA JUNKO; HUANG LIMING; FOWLER THOMAS; NOVAK ANDREW; MEGHANI PREMJI; BRAHMACHARY ENUGURTHI; YEAGER ADAM RICHARD
权利人:CELGENE INT II SÀRL
摘要:Compounds that bind the glucagon-like peptide 1 (GLP-1) receptor, methods of their synthesis, methods of their therapeutic and/or prophylactic use, and methods of their use in stabilizing GLP-1 receptor in vitro for crystallization of the GLP-1 receptor are provided. Certain compounds may have activity as modulators or potentiators with respect to glucagon receptor, GIP receptor, GLP-1 and GLP-2 receptors, and PTH receptor on their own or in the presence of receptor ligands such as GIP(1-42), PTH(1-34), Glucagon(1-29), GLP-2(1-33), GLP-1(7-36), GLP-1(9-36), oxyntomodulin and exendin variants.

专利号:RU-2202555-C2
优先权日:1994-01-28
标 题 :Bioconjugative complexes, method of their synthesis (variants), phenylborate complex- -forming cross-linking reagents, kit of agents or system, method of isolation of required cell population