CAS: 75-50-3; Trimethylamine

上下游产品

CAS号10496-93-2 4-(hydroxymethy... | CAS号1077-11-8 trimethyl(2-phe... | CAS号109448-61-5 trimethyl-[5-(5... | CAS号124-40-3 二甲胺 | CAS号74-89-5 氨基甲烷 | CAS号74-90-8 氢氰酸 | CAS号1002-26-2 hepta-1,3-diene | CAS号628-72-8 2,4-Heptadiene | CAS号10035-10-6 氢溴酸 | CAS号109671-05-8 2-hydroxyethyl(...

氯化胆碱置于乙二醇体系中,化学反应 6.0H,反应生成 三甲胺
参考文献:电化学的 分解 的 氯化胆碱 离子液体类似物
标题:电化学的 分解 的 氯化胆碱 离子液体类似物
摘要:对离子液体进行了深入的电化学研究,尤其是对离子液体的研究. 电沉积金属.本文研究了一种深共晶的电化学稳定性溶剂 基于 氯化胆碱 和 乙二醇在更长的电解时间内进行了研究.形成几种分解 产品如 2-甲基-1,3-二氧戊环被观测到.给出了形成这些产物的可能机理:有些产物在阳极或阴极发生反应,而另一些可以通过在两者处形成的反应产物的连续反应来解释.电极.一系列氯化产品,例如氯甲烷,二氯甲烷 和 氯仿也可以被检测到.随着氯没有观测到阳极上的气体.氯化产物的形成归因于存在氯化物.氯3−溶液中的离子.存在的氯3-通过光度法观测到离子.氯化产品的存在会给环境带来更大的影响,并给健康和安全带来更大的风险,并且对这些离子液体类似物的"绿色"提出了质疑.减少分解 的 溶剂,水并添加易氧化的酸作为"牺牲剂".他们对形成的影响2-甲基-1,3-二氧戊环被量化.但是,添加牺牲剂并不能提高稳定性.溶剂.除此之外甲酸
DOI:10.1039/b906318H

专利信息

专利号:US-6683189-B1
优先权日:1996-02-26
标 题 :Method for the synthesis of pyrrole and imidazole carboxamides on a solid support
发明人：DERVAN PETER B; BAIRD ELDON
权利人:CALIFORNIA INST OF TECHN
摘要:The present invention describes a novel method for the solid phase synthesis of polyamides containing imidazole and pyrrole carboxamides. The polyamides are prepared on a solid support from aromatic carboxylic acids and aromatic amines with high stepwise coupling yields (>99%), providing milligram quantities of highly pure polyamides. The present invention also describes the synthesis of analogs of the natural products Netropsin and Distamycin A, two antiviral antibiotics. The present invention also describes a novel method for the solid phase synthesis of imidazole and pyrrole carboxamide polyamide-oligonucleotide conjugates. This methodology will greatly increase both the complexity and quantity of minor-groove binding polyamides and minor-groove binding polyamide-oligonucleotide conjugates which can be synthesized and tested.

专利号:US-11466050-B2
优先权日:2014-09-29
标 题 :Method for peptide synthesis and apparatus for carrying out a method for solid phase synthesis of peptides
发明人：KNAUER SASCHA; ROESE TOBIAS MICHAEL LOUIS; AVRUTINA OLGA; KOLMAR HARALD; UTH CHRISTINA
权利人:SULFOTOOLS GMBH
摘要:The invention relates to a method for peptide synthesis, wherein said method comprises the steps of reacting a first amino acid or a first peptide with an α-amine protected second amino acid in a solvent selected from the group consisting of water, alcohol, and a mixture of water and alcohol, and removing the α-amine protecting group with a deprotecting solution. The invention further relates to protective agents, their use and an apparatus for carrying out a method for solid phase synthesis of peptides.

专利号:WO-2022256490-A9
优先权日:2021-06-03
标题:Improved synthesis of phosphoramidates for the treatment of hepatitis b virus
发明人：LOCKWOOD MARK
权利人:ANTIOS THERAPEUTICS INC
摘要:The synthesis of phosphoramidate prodrugs useful in the treatment of viral infections is disclosed. Specifically, an improved synthesis of phosphoramidate nucleotides useful in the treatment of Hepatitis B virus is disclosed.

专利号:US-7344863-B2
优先权日:1998-03-13
标题:Methods for producing polypeptides through enhanced synthesis of encoding nucleic acid molecules
发明人：LI WU-BO; JESSEE JOEL A; SCHUSTER DAVID; XIA JIULIN; GEBEYEHU GULILAT
权利人:INVITROGEN CORP
摘要:The present invention is directed to compositions and methods for enhancing synthesis of nucleic acid molecules, particularly GC-rich nucleic acid molecules. Specifically, the invention provides compositions comprising one or more nitrogen-containing organic compounds having a formula selected from the group consisting of formula I and formula II (or salts or derivatives thereof), preferably 4-methylmorpholine N-oxide or betaine (carboxymethyltrimethylammonium), and further comprising one or more compounds selected from the group consisting of proline and an N-alkylimidazole compound, and more preferably proline, 1-methylimidazole or 4-methylimidazole. The invention further relates to methods for enhanced, high-fidelity synthesis of nucleic acid molecules, including via amplification (particularly PCR), reverse transcription, and sequencing methods. The invention also relates to nucleic acid molecules synthesized by these methods, to fragments or derivatives thereof, and to vectors and host cells comprising such nucleic acid molecules, fragments, or derivatives. The invention also relates to kits for synthesizing, amplifying, reverse transcribing or sequencing nucleic acid molecules comprising one or more of the compositions of the invention.

专利号:US-12383499-B2
优先权日:2018-01-01
标题:Scale up synthesis of silicasome nanocarriers
发明人：NEL ANDRE E; MENG HUAN; LIU XIANGSHENG
权利人:UNIV CALIFORNIA
摘要:In order to facilitate the approval and commercialization of silicasome drug delivery systems (e.g. irinotecan silicasomes) it is necessary to scale up synthesis of the drug-loaded silicasomes. In this regard, it was discovered that the synthesis protocols used for laboratory synthesis of drug-loaded silicasomes (e.g., 500 mg/batch) do not scale to large scale silicasome production, because the resulting products were too heterogeneous for use as pharmaceuticals. Accordingly, new methods are provided herein that effectively afford the large-scale production of mesoporous silica nanoparticles (MSNPs) and lipid bilayer coated MSNPs (silicasomes).

专利号:US-6048975-A
优先权日:1991-09-12
标 题:Process for the chemical synthesis of oligonucleotides
发明人：PFLEIDERER WOLFGANG; BERGMANN FRANK
权利人:HOECHST AG
摘要:A process for the chemical synthesis of oligonucleotides n Use of a dansylethoxycarbonyl group as base-labile 5'-hydroxyl protective group in the chemical synthesis of DNA and RNA and suitable synthetic processes. n The ease of detection of the dansyl protective group and the ease of elimination from the sugar residue of the nucleotide without side reactions make oligonucleotide synthesis possible with high yields in very small quantities.