专利号:US-7276637-B2 优先权日:2002-08-02 标题:Synthesis of cyclohexanone derivatives 发明人:BRANDS KAREL MARIE JOSEPH; DAVIES ANTONY JOHN; OAKLEY PAUL JOSEPH; SCOTT JEREMY PETER; SHAW DUNCAN EDWARD; TEALL MARTIN RICHARD 权利人:MERCK & CO INC 摘要:A novel process for preparing cyclohexanone derivatives of formula (I) n nis described. The products are useful as gamma secretase inhibitors, or as intermediates in the synthesis of other gamma secretase inhibitors.
专利号:WO-2024031876-A1 优先权日:2022-08-10 标题 :Method for one-step synthesis of methylcyclopentadiene from cyclopentanone and methanol 发明人:LI NING; ZOU ZHUFAN; LI GUANGYI; ZHANG TAO; WANG AIQIN; WANG XIAODONG; CONG YU 权利人:DALIAN INST CHEM & PHYSICS CAS 摘要:The present invention relates to a method for one-step synthesis of methylcyclopentadiene from cyclopentanone and methanol. Cyclopentanone and methanol are used as raw materials, and are subjected to a cascade dehydrogenation/aldol condensation/selective hydrodeoxygenation reaction in a continuous packed bed reactor under the action of an A x B y O z composite metal oxide catalyst, so as to synthesize a target product, i.e., methylcyclopentadiene. The present invention has a simple process line, is convenient for catalyst preparation, is environmentally friendly, and achieves direct conversion from cyclopentanone and methanol to high value-added methylcyclopentadiene.
专利号:US-12157751-B2 优先权日:2021-05-12 标题 :Process for the synthesis of oligomeric siloxane having sulfone moiety, and silicon-containing compounds having sulfone moiety 发明人:SINGHAL PRAVEEN KUMAR; TARAFDAR GOURAV; RAMESH APEKSHA 权利人:MOMENTIVE PERFORMANCE MAT INC 摘要:There is provided herein a process for the synthesis of sulfonyl silanes. There is also provided herein various sulfenylated and sulfonylated silicon-containing compounds made by the process.
专利号:US-7531694-B2 优先权日:2004-07-07 标题:Process for synthesis of 4-4′-diamino-diphenyl-sulfone 发明人:VILLA MARCO; DE FAVERI CARLA; ZANOTTI RICCARDO; CIARDELLA FRANCESCO; BORIN FABRIZIO 权利人:LUNDBECK PHARMACEUTICALS ITALY 摘要:A new process for the preparation and purification of 4-4′-diamino-diphenyl-sulfone (dapsone) is described. The process described is a three step process comprising a condensation reaction with the synthesis of a thioether intermediate and then steps of oxidation and reduction in suitable conditions in order to obtain a product with good yield and purity.
专利号:WO-2024091204-A1 优先权日:2022-10-27 标题 :An electrochemical method for the synthesis of high purity tungsten blue in solid form 发明人:SAHIN YUCEL; ARVAS MELIH BESIR; YAZAR AYDOGAN SIBEL 权利人:UNIV YILDIZ TEKNIK; ISTANBUL UNIV CERRAHPASA REKTORLUGU 摘要:The invention relates to a short-time, low-cost and environmentally friendly electrochemical method for the single-step synthesis of high purity tungsten blue using an electrochemical system. Said electrochemical system comprises a potentiostat (1), electrolyte (5), a working electrode (2) connected to the potentiostat (1) and immersed in the electrolyte (5), a counter electrode (3) connected to the potentiostat (1) and immersed in the electrolyte (5), and a reference electrode (4) connected to the potentiostat (1) and immersed in the electrolyte (5).
专利号:US-10807962-B2 优先权日:2017-04-14 标 题 :Process for the synthesis of firocoxib 发明人:CELESTINI PAOLO; BARETTI SERGIO; PIZZATTI ENRICA 权利人:COSMA S P A 摘要:The present invention concerns a process for the preparation of firocoxib, i.e. 3-(cyclopropylmethoxy)-5,5-dimethyl-4-(4-methylsulfonylphenyl)-furan-2-one, comprising steps (a)-(g), wherein the process provides for step (d) of the reaction of a new intermediate, i.e. 2-methyl-1-[4-(methylsulfanyl)phenyl]-1-oxopropan-2-yl (acetyloxy)acetate (compound VII) in the same organic solvent of step (a) in the presence of a catalyst and a phase transfer catalyst solution in the same organic solvent with hydrogen peroxide.