CAS: 1445-69-8; 2,3-Dihydrophthalazine-1,4-Dione

相似化合物

76240-49-8 20116-66-9 3682-29-9

上下游产品

CAS号484-23-1 双肼屈嗪 | CAS号19064-73-4 4-溴-1(2H)-酞嗪酮 | CAS号3660-90-0 1,4-二溴酞嗪 | CAS号27702-18-7 N,N-bis[(2-chlo... | CAS号27702-22-3 Benzaldehyde, 2... | CAS号27702-33-6 2-Propenal, 3-p... | CAS号27702-28-9 Benzaldehyde, 3... | CAS号27702-20-1 Benzaldehyde,4-... | CAS号2257-69-4 4-氯-1(2H)-酞嗪酮 | CAS号51935-42-3 1-氯-4-肼基酞嗪

邻苯二甲酸二甲酯置于一水合肼体系中,用 甲醇 用作溶剂,以89%的收率获得邻苯二甲酰肼
参考文献:基于酰肼单体和三聚体的超低分子量刺激响应和多功能超分子凝胶.
标题:基于酰肼单体和三聚体的超低分子量刺激响应和多功能超分子凝胶.
摘要:越简单越好.设计并合成了一系列简单,中性和超低分子量(mw:140-200)的酰肼类超分子凝胶剂,并通过两个简单的步骤进行了合成.对于非共轭的衍生自环己烷的酰肼,它们的单体可以通过分子间氢键和偶极-偶极相互作用自组装形成凝胶.重要的是,共轭邻苯二甲酰肼可以通过分子间氢键自聚集成平面和圆形三聚体,然后通过分子间π-π堆积相互作用自组装形成凝胶.有趣的是,这些简单的胶凝剂表现出不同寻常的特性,例如自我修复,多响应荧光以及手性(R)/(S)-1,1'-联萘-2,2'-二胺和s 2−分别通过不同的凝胶重整时间和蓝绿色变色时间.这些结果强调了超分子凝胶的重要性,并扩展了超分子胶凝剂的范围.
Doi:10.1002/asia.202001041

专利信息

专利号:US-2022267266-A1
优先权日:2019-07-09
标 题 :Improved, cost effective process for synthesis of vitamin d3 and its analogue calcifediol from ergosterol
发明人：DATLA ANUPAMA; NAGRE PRASHANT; TAMORE JAGDISH; PRABHU MANOJKUMAR SADANAND; KADAM SACHIN VASANT
权利人:FERMENTA BIOTECH LTD
摘要:Disclosed herein is an improved and efficient process for synthesis of vitamin D3 and its analogue Calcifediol from Ergosterol. Particularly, the present invention discloses the synthesis of key intermediate 3β-tert-Butyldimethylsilyloxy-22-hydroxy-23,24-bisnorchola-5,7-diene (5), and novel intermediate β-tert-Butyldimethylsilyloxy-22-iodo-23,24-bisnorchola-5,7-diene (9) by a simple and cost effective process. The industrially viable processes for preparation of said intermediate(s) results in providing provitamins with various side chains and the desired products in high yield.

专利号:US-8415510-B2
优先权日:2008-02-28
标题 :Synthesis of a PEG-6 moiety from commercial low-cost chemicals
发明人：ENGELL TORGRIM
权利人:ENGELL TORGRIM; GE HEALTHCARE LTD
摘要:The present invention provides novel synthesis's for obtaining a protecting group aminoxy PEG-6 linker from cost effective, and readily available starting materials and chemicals or modified polyethylene glycols. More specifically, a novel synthesis of obtaining a modified Boc-protected aminoxy PEG-6 linker was achieved so that said linker may be attached to a vector such as a peptide based fragment.

专利号:US-8536375-B2
优先权日:2008-12-22
标题:Synthesis of obtaining modified polyethylene glycol intermediates
发明人：ENGELL TORGRIM
权利人:ENGELL TORGRIM; GE HEALTHCARE LTD
摘要:The present invention provides novel and more efficient synthesis's for obtaining an intermediate in the synthesis of obtaining a protecting group aminoxy PEG linker.

专利号:US-7485718-B2
优先权日:2005-06-16
标题:Chemical synthesis of low molecular weight polyglucosamines and polygalactosamines
发明人：SABESAN SUBRAMANIAM
权利人:DU PONT
摘要:A process for the synthesis of beta linked low molecular weight polymers of galactosamine and glucosamine has been developed. Through the use of high amounts of activating agents, efficient coupling of stable monomers is achieved. Using this process, chain extension is through the addition of single monomers, providing populations of single chain length polyhexosamines.

专利号:US-6632942-B2
优先权日:2000-05-04
标题:Asymmetric synthesis of piperazic acid and derivatives thereof
发明人：ROBIDOUX ANDREA L C; SERAFINI SIRO; DIETERICH PETRA; LEONARDI STEFANIA; STIBBARD JOHN
权利人:VERTEX PHARMA
摘要:This invention provides a concise, asymmetric synthesis of piperazic acid and derivatives thereof, whereby either the (3S)- or (3R)-enantiomeric form may be obtained with high optical purity. (3S)-piperazic acid is derived from D-glutamic acid through an (R)-2,5-dihydroxyvalerate ester intermediate. After the hydroxy groups are converted to suitable leaving groups, such as mesylates, the ester is treated with a bis-protected hydrazine to provide the desired (3S)-piperazic acid derivative. The (3R) enantiomer of piperazic acid may be similarly obtained starting with L-glutamic acid. The method may also be used to obtain piperazic acid derivatives that have moderate optical purity or are racemic. By this method, piperazic acid derivatives may be obtained that are useful as intermediates for pharmacologically active compounds. For example, certain intermediates of this invention are useful for preparing caspase inhibitors, particularly inhibitors of ICE, through additional steps known in the art.

专利号:US-5679773-A
优先权日:1995-01-17
标题 :Reagants and methods for immobilized polymer synthesis and display
发明人：HOLMES CHRISTOPHER P
权利人:AFFYMAX TECH NV
摘要:Compounds and methods for solid phase synthesis of organic molecules including peptides, oligonucleotides, benzodiazepines, beta -turn mimetics, and prostaglandins. The present invention provides new reagents in the form of linking groups and resins and substrates having attached linking groups which are useful in solid phase synthesis of high density arrays of organic molecules. The invention also provides methods which increase yields of various organic synthesis strategies.