CAS: 17465-86-0; ?-Cyclodextrin

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CAS号9005-25-8 马铃薯淀粉 | CAS号10016-20-3 α-环糊精 | CAS号97-30-3 甲基葡萄糖苷 | CAS号87832-35-7 | CAS号77192-53-1 prostacyclin*γ-... | CAS号51166-71-3 2,6-二-O-甲基-β-环糊精 | CAS号7585-39-9 β-环糊精 | CAS号97227-33-3 单-6-O-对甲苯磺酰-Γ-环糊精 | CAS号97227-32-2 单-2-O-(对甲苯磺酰)-γ-环糊精 | CAS号129499-78-1 抗坏血酸葡糖苷

α-环糊精置于四苯硼钠,麦芽六糖体系中,用 Aq. Phosphate Buffer 用作溶剂,化学反应生成γ-环糊精
参考文献:酶介导的动态组合化学可实现大环寡糖的不平衡模板指导的合成.
标题:酶介导的动态组合化学可实现大环寡糖的不平衡模板指导的合成.
摘要:我们表明,可以通过使用人工模板分子在酶介导的动态系统中指导特定产物的自组装来控制和控制酶促反应的结果.具体来说,我们利用糖基转移酶生成相互转化的线性和大环α-1,4-D-葡聚糖(环糊精)的复杂动态混合物.我们发现,天然环糊精(α,β和γ)是作为动态捕获子系统的一部分失衡形成的,它出人意料地像在热力学控制下的动态组合库(dcl)一样瞬态运行.通过添加不同的模板,我们可以以89-99%的选择性促进每种天然环糊精的合成,或者,我们可以扩增每个大环具有9个和10个葡萄糖单元的不寻常的大环环糊精(δ和ε)的合成.在没有模板的情况下,瞬时dcl持续不到一天,并且环糊精会迅速转化为短麦芽低聚糖.模板可稳定动力学捕获的子系统,从而实现鲁棒的环糊精选择性合成,如在单个反应容器中环糊精的高产率顺序相互转化所证明的.我们的结果表明,只要在热力学和动力学控制之间达到适当的平衡,模板就可以指导不平衡的自组装,并可以
Doi:10.1039/c9Sc03983J

专利信息

专利号:US-6239313-B1
优先权日:2000-02-16
标 题 :Process for the solid state synthesis of enantiopure B-aminoalcohols from racemic epoxides
发明人：KAKULAPATI RAMA RAO; NANDURI BHANUMATHI; ELETI RAJENDER REDDY
权利人:COUNCIL SCIENT IND RES
摘要:The invention relates to a process for the solid state synthesis of enantiopure β-aminoalcohols by preparing inclusion complexes of aryloxyepoxide with cyclodextrin by adding an epoxide in equimolar ratio in an organic solvent to an aqueous solution of cyclodextrin, reacting the cyclodextrin complex of aryloxyepoxide with a nucleophile in solid state by intimately grinding the mixture using a mortar and pestle, continuing the mixing till the starting epoxide disappeared on tic, removing excess amines under vacuum, extracting the β-aminoalcohols produced with a solvent with yields of more than 50% and enantioselectivity of upto 100%.

专利号:US-2022169753-A1
优先权日:2019-03-29
标 题:An improved process for preparation of sugammadex acid and sugammadex sodium
发明人：SRIDHAR BHUVANESWARI; KUDAVALLI JAYA SATYANARAYANA; MEDABALIMI PETERPAUL RAJU; REMALA NAGA MALLESH; DEVINENI SURESH; RAMACHANDRAN GURURAJ; JAGANATHAN THANNEERPANDALPUDUR SRINIVASAN; KALIAPERUMAL KARTHIKEYAN
权利人:HOSPIRA INC
摘要:The present disclosure provides an improved process for the synthesis of suganmmadex acid and suganmmadex sodium.

专利号:US-9120876-B2
优先权日:2010-08-25
标 题 :Process for preparation of Sugammadex
发明人：DAVULURI RAMAMOHAN RAO; PONNAIAH RAVI; SRIBHASHYAM RAVI KANTH; VALSAN NANDKUMAR MECHERILI; DONGARI NARESH; CHLNV PRASAD; BATTHINI GURUSWAMY
权利人:DAVULURI RAMAMOHAN RAO; PONNAIAH RAVI; SRIBHASHYAM RAVI KANTH; VALSAN NANDKUMAR MECHERILI; DONGARI NARESH; CHLNV PRASAD; BATTHINI GURUSWAMY
摘要:A novel process for the preparation of 6-perdeoxy-6-per-halo Gamma cyclodextrin which is a useful intermediate in the synthesis of Sugammadex is disclosed in the invention. The process involves reacting Gamma cyclodextrin with phosphorous halide in the presence of organic solvent.

专利号:US-8618182-B2
优先权日:2010-07-29
标题 :Process for synthesizing C5+ hydrocarbons in the presence of a catalyst prepared using at least one cyclic oligosaccharide
发明人：DIEHL FABRICE; GRIBOVAL-CONSTANT ANNE; KHODAKOV ANDREI; JEAN-MARIE ALAN; MONFLIER ERIC
权利人:DIEHL FABRICE; GRIBOVAL-CONSTANT ANNE; KHODAKOV ANDREI; JEAN-MARIE ALAN; MONFLIER ERIC; IFP Energies Nouvelles
摘要:C5+ hydrocarbon synthesis by contracting a synthesis gas with a catalyst naming at least one metal from group VIII deposited on a support formed by at least one oxide, said catalyst being prepared using a process of at least:n i) contracting at least the support with at least one solution containing at least one precursor of metal from group VIII; ii) contracting at least the support with at least one organic compound formed from at least one cyclic oligosaccharide composed of at least 6 α-(1,4)-bonded glucopyranose subunits; iii) at least one calcining to obtain at least the metal from group VIII in the oxide form; i) and ii) being carried out separately, in any order, or simultaneously.