CAS: 30683-23-9; 3-Bromopyridine-2-Carboxylic Acid

相似化合物

55758-02-6 53636-56-9 1260807-49-5

上下游产品

CAS号55758-02-6 3-溴-2-氰基吡啶 | CAS号188677-47-6 3-bromo-N-pheny... | CAS号10354-53-7 N-苯基吡啶甲酰胺 | CAS号53636-56-9 3-溴吡啶甲酸甲酯

N-苯基吡啶甲酰胺置于盐酸,正丁基锂,Substituted 1,2-Dibromoethane体系中,化学反应 15.0H,反应生成3-溴-2-吡啶羧酸
参考文献:有机锂化合物在有机合成中的应用.十九.基于芳香金属化的合成策略.3-卤代吡啶甲酸和异烟酸的简明区域特异性合成
标题:有机锂化合物在有机合成中的应用.十九.基于芳香金属化的合成策略.3-卤代吡啶甲酸和异烟酸的简明区域特异性合成
摘要:摘要 通过苯胺 (1) 和 (2) 的金属化 (N-Buli),然后生成的双锂化苯胺与卤化剂 (Ccl3描述了-Ccl3,Ch2Br-Ch2Br,I2),随后对(3) 和(4) 进行酸性水解,作为将甲基吡啶和异烟碱酸区域特异性转化为其c3 卤代衍生物的一种方式.
Doi:10.1080/00397919708003053

专利信息

专利号:US-RE41998-E
优先权日:1990-02-26
标题 :Compositions and methods of treatment of sympathetically maintained pain
发明人：CAMPBELL JAMES N
权利人:ARCLON THERAPEUTICS INC
摘要:Sympathetically maintained pain is treated topically by administering to the site where sympathetically maintained pain is present an α-1-adrenergic antagonist, α-2-adrenergic agonist, or other drug that depletes or blocks synthesis of sympathetic norepinephrine, known collectively as sympatholytic agents. Chemical formulas for several sympatholytic agents are given.

专利号:US-2010004245-A1
优先权日:2006-10-20
标 题:Azacycloalkane derivatives as inhibitors of stearoyl-coenzyme a delta-9 desaturase
发明人：OBALLA RENATA M; DESCHENES DENIS; GAGNON MARC; LEBLANC YVES; POWELL DAVID; RAMTOHUL YEEMAN K
权利人:MERCK FROSST CANADA LTD
摘要:Azacycloalkane derivatives of structural formula (I) are selective inhibitors of stearoyl-coenzyme A delta-9 desaturase (SCD1) relative to other known stearoyl-coenzyme A desaturases. The compounds of the present invention are useful for the prevention and treatment of conditions related to abnormal lipid synthesis and metabolism, including cardiovascular disease, such as atherosclerosis; obesity; diabetes; neurological disease; metabolic syndrome; insulin resistance; and liver steatosis.

专利号:CN-109422729-B
优先权日:2017-08-27
标题:A class of chiral azapolycyclic alkaloids and synthesis method thereof

专利号:CN-109422728-B
优先权日:2017-08-27
标题 :A class of azetidine derivatives and synthesis method thereof

专利号:CN-109422728-A
优先权日:2017-08-27
标题:A class of azetidine derivatives and synthesis method thereof

专利号:CN-109422729-A
优先权日:2017-08-27
标 题:A class of chiral azapolycyclic alkaloids and synthesis method thereof