专利号:US-4638032-A 优先权日:1983-12-12 标 题 :Magnetic particles as supports for organic synthesis 发明人:BENNER STEVEN A 权利人:GENETICS INST 摘要:A support system for organic synthesis comprising magnetic particles in a dispersion medium covalently attached to functional groups having affinity for polymer subunits, and methods for making and using the support system, e.g. for synthesis of oligodeoxynucleotides and polypeptides.
专利号:US-11738328-B2 优先权日:2021-04-30 标题:Single-step synthesis of chemisorption fiber sorbents (CHEFS) for the capture of CO2 and removal of water contaminants 发明人:GRAY MCMAHAN L; SHI FAN; YI SHOULIANG; WILFONG WALTER CHRIS; WANG QIUMING 权利人:US ENERGY 摘要:One or more embodiments relates to method for generating CHEFS having the steps of generating the CHEFS from a dope. One or more embodiments relates to a method for generating CHEFS having amine functional groups having the steps of generating a dope containing a BIAS with amine groups, at least one polymer, and at least one solvent; and forming CHEFS from the dope, wherein the generated CHEFS have no more than 30% amine loss compared to the BIAS.
专利号:US-8729257-B2 优先权日:2009-07-17 标题 :Hybrid lipid compounds based on pentaerythritol, intermediates, preparation methods and use thereof 发明人:DAI ZHIFEI; LIANG XIAOLONG; YUE XIULI 权利人:DAI ZHIFEI; LIANG XIAOLONG; YUE XIULI; HARBIN INST OF TECHNOLOGY 摘要:This invention relates to a novel class of hybrid lipid compound based on pentaerythritol, their intermediates, preparation methods and uses thereof. Different kinds of functional groups such as alkyl chain, siloxane group, azobenzene, porphyrins, cholesterol, benzene ring and carboxyl were introduced into the four hydroxyl groups of pentaerythritol through chemical reaction to obtain the final hybrid lipid compounds based on pentaerythritol. Cerasomes prepared from such lipids have uniform size, silicate network surface, good stability and biocompatibility, and the leakage of drugs is not easy. The present liposome can be used as functional materials such as drugs or drug carriers, or used for optical storage and molecular devices, simulation, design and synthesis of artificial systems, nano-composite membrane materials and the removal of organic pollutants, etc., in addition, the preparation method of the present invention is simple, and it is easy for industrial production.
专利号:US-4473695-A 优先权日:1982-01-15 标 题:Synthesis of N,N'-dialkyl-4'bipyridinium reagents 发明人:WRIGHTON MARK S; BOOKBINDER DANA C 权利人:MASSACHUSETTS INST TECHNOLOGY 摘要:A novel class of dialkyl and dialkyl-aromatic viologens (4,4'dipyridinium compounds) and their salts which may be polymerized and covalently bonded to electrodes for use in electronic display systems.
专利号:US-9470680-B2 优先权日:2011-02-28 标 题:Fluorescence-based approach to monitor release factor-catalyzed termination of protein synthesis 发明人:GONZALEZ JR RUBEN L; STERNBERG SAMUEL H; PULUKKUNAT DILEEP K 权利人:GONZALEZ JR RUBEN L; STERNBERG SAMUEL H; PULUKKUNAT DILEEP K; UNIV COLUMBIA 摘要:Provided are probes comprising a class 1 release factor conjugated to a fluorescent label and methods of making the probes. Also provided are methods for detecting conformational changes in ribosomes and associated molecules, such as class 1 release factors. In addition, methods of identifying a compound for reducing nonsense-mediated decay of mRNA and/or for inhibiting termination of protein synthesis at a premature stop codon, are described. Methods of assaying RF3 activity are also included.
专利号:US-2022347654-A1 优先权日:2021-04-30 标题 :Single-Step Synthesis of CHEmisorption Fiber Sorbents (CHEFS) for the Capture of CO2 and Removal of Water Contaminants
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