CAS: 543-20-4; Succinyl Chloride

上下游产品

succinic acid anhydride Dichloromethyl methyl ether (E)-3-Ureido-but-2-enoic acid ethyl ester succinic acid4-oxo-4-thiophen-2-yl-butyric acid all-trans-retinyl estersuccinic acid di-all-trans-retinyl ester succinic acid anhydride Succinyl Dicyanide

丁二酸置于草酰氯,N,N-二甲基甲酰胺体系中,用 二氯甲烷 作为反应溶剂,化学反应 4.0H,反应生成 丁二酰氯
参考文献:新型化合物的鉴定和结构-活性关系增强了大肠杆菌中抗生素的活性
标题:新型化合物的鉴定和结构-活性关系增强了大肠杆菌中抗生素的活性
摘要:在革兰氏阴性细菌中,外排泵能够防止多种抗生素达到有效的细胞浓度.充当外排泵抑制剂(epi)的小分子佐剂有可能使现有的由于外排机制无效的抗生素恢复活力.通过严格的实验筛选和计算机虚拟筛选的组合,我们最近确定了与膜融合蛋白acra相互作用的新型epi,Acra是大肠杆菌中acrab-Tolc外排泵的关键组件.在本文中,我们介绍了围绕先前提到的命中之一nsc 60339(1)的初步优化工作以及结构与活性之间的关系.通过这些努力,我们确定了两种化合物,Slupp-225(17小时)和slupp-417(170),它表现出非常好的特性,如潜在环境绩效指标大肠杆菌细胞,包括渗透外膜的能力,改进的相对流出的抑制作用1新生霉素的活性的,和增强和红霉素.
DOI:10.1021/acs.Jmedchem.7B00453

专利信息

专利号:US-2020148541-A1
优先权日:2017-06-01
标题 :An approach to a bottom-up synthesis of nanocarbons
发明人：GIDRON ORI; PHATANGARE SUNITA; DISHI OR; BEDI ANJAN
权利人:YISSUM RES DEV CO OF HEBREW UNIV JERUSALEM LTD
摘要:Provided is a method for the synthesis of a Ï€-conjugated system from oligofurans, under conditions involving cycloaddition.

专利号:US-7122693-B2
优先权日:1988-04-11
标题 :Acetaldehyde acetal compounds, their synthesis, and uses thereof
发明人：BELLEAU EXECUTRIX OF ESTATE PI; DIXIT DILIP M; NGUYEN-BA NGHE
权利人:SHIRE BIOCHEM INC
摘要:The acetaldehyde compounds, 2-thiobenzoylacetaldehyde diethylacetal, 2-benzoyloxyacetaldehyde bis(2-methoxyethyl)acetal, 2-hydroxyacetaldehyde bis( 2-methoxyethyl)acetal, 2-thiobenzoylacetaldehyde bis(2-methoxy-ethyl)acetal, and 2-thioacetaldehyde bis(2-methoxyethyl)acetal, are useful as intermediates in the synthesis of substituted 1,3-oxathiolanes and substituted 1,3-dioxolanes.

专利号:US-8420850-B2
优先权日:2010-05-14
标 题:Compounds for the synthesis of biostable polyurethane, polyurea or polyurea urethane polymers
发明人：DUOCASTELLA CODINA LLUIS; MOLINA MARIA; ARAD OFIR; BORRELL BILBAO JOSE IGNACIO; GARCIA DAVID SANCHEZ; PETTERSON SALOM SOFIA HENRIETTE
权利人:DUOCASTELLA CODINA LLUIS; MOLINA MARIA; ARAD OFIR; BORRELL BILBAO JOSE IGNACIO; GARCIA DAVID SANCHEZ; PETTERSON SALOM SOFIA HENRIETTE; IBERHOSPITEX SA
摘要:The invention comprises compounds which are derived from a drug or a substance with therapeutic properties, and useful as reagents for the synthesis of biostable polymers including said drug in their backbone, namely polyurethanes, polyureas or polyurea urethanes that are biocompatible and biostable. The invention also comprises the processes for preparing the compounds and the polymers, and to the use of these polymers for the manufacture of medical devices.

专利号:US-6090934-A
优先权日:1996-10-20
标 题:Universal support for the synthesis of oligonucleotides
发明人：KUMAR PRADEEP; GUPTA KAILASH CHAND
权利人:COUNCIL SCIENT IND RES; DBT GOVERNMENT OF INDIA
摘要:A universal polymer support containing an organic aliphatic molecule of structure ##STR1## having at least a pair of cis-hydroxyl groups where one of the hydroxyl groups is attached to the polymer support through a covalent linkage and the other hydroxyl group is protected by an acid labile group.

专利号:EP-0542969-B1
优先权日:1991-06-04
标 题:Biodegradable particulate vector and method of synthesis
发明人：SAMAIN DANIEL; DE MIGUEL IGNACIO; MENIALI JAOUAD; IOUALALEN KARIM; DING LI; CERVILLA MONIQUE; RIEUMAJOU VALERIE; DELRIEU PASCAL; IMBERTIE LAURENT
权利人:BIOVECTOR THERAPEUTICS SA
摘要:A biodegradable particulate vector is disclosed and is characterized in that it comprises: a nucleus consisting of a cross-linked polysaccharide or oligosaccharide matrix to which ionic ligands are attached; a first semi-permeable lipid layer linked to the nucleus by covalent bonds; a second layer of amphiphilic compounds linked to the first lipid layer by hydrophobic interactions. A method for synthesis of said vector is also disclosed.

专利号:US-2023111600-A1
优先权日:2019-12-17
标题 :Polymeric fatty acid compounds for the treatment of fibrous amino acid-based substrates, especially hair
发明人：WAGNER ROLAND; STREICHER KATHARINA; ROHMANN LAURA; WENSKE CHRISTIAN; HAVELI SHRUTISAGAR DATTATRAYA
权利人:MOMENTIVE PERFORMANCE MAT GMBH
摘要:The present invention is directed at mono-, di- or polyquaternary ammonium compounds of the formula (I) wherein x is 1 to 50, and F can be the same or different and is represented by the general formula (II) wherein at least one of the optionally substituted and optionally functional-group-containing hydrocarbon radicals R 1 , R 2 , R 3 , R 4 or R 5 contains at least one estolide moiety comprising two or more ester or amide moieties. The invention also relates to a process for the synthesis of such compounds, the use of the compounds in cosmetic formulations for skin and hair care, cosmetic compositions for the treatment of fibers, and compositions containing one or more of the compounds for the treatment of hair.