专利号:WO-2020121335-A1 优先权日:2018-12-14 标题:A process for producing tirucalladienol for synthesis of limonoids 发明人:HIREKODATHAKALLU VENKATARAMAIAH THULASIRAM; PANDREKA AVINASH; PATIL CHAYA SHIVANAGOUDA 权利人:COUNCIL SCIENT IND RES 摘要:The invention relates to the construction of recombinant DNA constructs encoding tirucalladienol synthase; and squalene epoxidase operably linked to a regulatory sequence. The production of tricualldienol in a yeast is increased by coexpression with squalene epoxidase. Further, tirucalladeinol synthase engineering leads to increase in the efficiency of the synthesis process towards tirucalladienol.
专利号:US-9976167-B2 优先权日:2012-12-06 标题:Group of glycosyltransferases and use thereof 发明人:ZHOU ZHIHUA; YAN XING; FAN YUN; WANG PINGPING; WEI YONGJUN; WEI WEI; ZHANG JUN 权利人:SHANGHAI INST BIOLOGICAL SCIENCES CAS 摘要:Provided are the use of glycosyltransferases gGT25, gGT13, gGT30, gGT25-1, gGT25-3, gGT25-5, gGT29, gGT29-3, gGT29-4, gGT29-5, gGT29-6, gGT29-7, 3GT1, 3GT2, 3GT3, 3GT4 and derived polypeptides therefrom in the catalyzed glycosylation of terpenoid compounds and the synthesis of new saponins, wherein the glycosyltransferases can specifically and efficiently catalyze tetracyclic triterpenoid compound substrates at positions C-20 and/or C-6 and/or C-3 during hydroxyl glycosylation, and/or transfer the glycosyl from a glycosyl donor to the first glycosyl of the tetracyclic triterpenoid compounds at position C-3, so as to extend the sugar chain. The glycosyltransferases can also be used for constructing man-made synthetic rare ginsenosides and a variety of new ginsenosides and derivatives thereof.
专利号:US-10675313-B2 优先权日:2005-11-17 标 题 :HAS2-stimulating plant extracts 发明人:PERRIER ERIC; GUEZENNEC ANNE; REYMERMIER CORINNE; GUESNET JOELLE 权利人:PERRIER ERIC; GUEZENNEC ANNE; REYMERMIER CORINNE; GUESNET JOELLE; BASF Beauty Care Solutions France; SAINT LAURENT PARFUMS 摘要:The invention relates to plant extracts for stimulating the synthesis of hyaluronan synthase, particularly the synthesis of hyaluronan synthase 2 (HAS2). Specific aims of the invention are to increase firmness and/or elasticity and/or tissue moisturization, and/or increase the skin barrier effect, and/or increase tissue resilience, and/or modulate angiogenesis, or the neocreation of blood capillaries, and/or improve healing, and/or cell proliferation, migration or differentiation, and/or skin atrophy, and/or intended to combat the effects of ageing on the skin, and in particular to combat the loss of firmness of the skin observed in the course of ageing, and/or atrophied scars.
专利号:CN-114836398-A 优先权日:2022-06-06 标题 :Application of glycosyltransferase mutants in the directed synthesis of unnatural ginsenosides
专利号:CN-106701647-A 优先权日:2016-09-27 标题 :Application of Gynostemma Gynostemma Glycosyltransferase in the Synthesis of Rare Ginsenosides
专利号:CN-114836398-B 优先权日:2022-06-06 标 题:Application of Glycosyltransferase Mutants in Directed Synthesis of Unnatural Ginsenosides
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合成参考文献
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