CAS: 89-61-2; 2,5-Dichloronitrobenzene

上下游产品

para-dichlorobenzene 2-nitro-4-chlorobenzenediazonium cation 3,6-dichloro-2-nitro-benzaldehyde 3,4-dinitroaniline 1-(4-chloro-2-nitrophenyl)piperidine 4-(4-chloro-2-nitro-phenyl)morpholine N-(4-chloro-2-nitrophenyl)pyridin-2-amine 1-(4-chloro-2-nitro-phenyl)-hexahydro-azepine

专利信息

专利号:US-8188282-B2
优先权日:2006-07-15
标 题:Regioselective palladium catalyzed synthesis of benzimidazoles and azabenzimidazoles
发明人：ALONSO JORGE; LINDENSCHMIDT ANDREAS; NAZARE MARC; HALLAND NIS; RKYEK OMAR; URMANN MATTHIAS
权利人:ALONSO JORGE; LINDENSCHMIDT ANDREAS; NAZARE MARC; HALLAND NIS; RKYEK OMAR; URMANN MATTHIAS; SANOFI AVENTIS
摘要:The present invention relates to a process for the regioselective synthesis of compounds of the formula I, n nwherein R0; R1; R2; R3; R4; R5; A1; A2; A3; A4, Q and J have the meanings indicated in the claims. The present invention provides a direct palladium catalyzed, regioselective process to a wide variety of unsymmetrical, multifunctional N-substituted benzimidazoles or azabenzimidazoles of formula I starting from 2-halo-nitroarenes and N-substituted amides useful for the production of pharmaceuticals, diagnostic agents, liquid crystals, polymers, herbicides, fungicidals, nematicidals, parasiticides, insecticides, acaricides and arthropodicides.

专利号:EP-2173747-B1
优先权日:2007-06-26
标 题:A regioselective metal catalyzed synthesis of annelated benzimidazoles and azabenzimidazoles
发明人：ALONSO JORGE; LINDENSCHMIDT ANDREAS; NAZARE MARC; R KYEN OMAR; URMANN MATHIAS; HALLAND NIS
权利人:SANOFI SA
摘要:The present invention relates to a process for the regioselective synthesis of compounds of the formula I, wherein R1; R2; R3; R4; J1; J2; J3; J4 and G have the meanings indicated in the claims. The present invention provides a direct metal, e.g. palladium or copper, catalyzed, regioselective process to a wide variety of unsymmetrical, multifunctional N-substituted benzimidazoles or azabenzimidazoles of formula I starting from 2-halo-nitroarenes and N-substituted amides.

专利号:US-4138404-A
优先权日:1973-03-22
标题:Process for the preparation of oxadiazolines
发明人：FORT JEAN F; GIRAUDON RAYMOND
权利人:RHONE POULENC SA
摘要:Oxadiazoline derivatives of the formula: ##STR1## WHEREIN R is alkyl of 1 through 4 carbon atoms, which are useful as intermediates in the synthesis of oxadiazoline derivatives of the formula: ##STR2## WHEREIN R is as defined above the R 1 is alkyl of 1 through 4 carbon atoms, possessing useful herbicidal properties, are prepared by a new process which comprises reducing the nitro group in a 5-alkyl-3-(2-nitro-4-chlorophenyl)-1,3,4-oxadiazolin-2-one of the formula: ##STR3## wherein R is as defined above to a hydroxylamino group, treating the resulting 5-alkyl-3-(2-hydroxylamino-4-chlorophenyl)-1,3,4-oxadiazolin-2-one with concentrated sulphuric acid of density about 1.83 to produce the corresponding amino-phenol, and converting the amine group in the resulting 5-alkyl-3-(2-amino-4-chloro-5-hydroxyphenyl)-1,3,4-oxadiazolin-2-one to a chlorine atom. The 5-alkyl-3-(2-hydroxylamino-4-chlorophenyl)-1,3,4-oxadiazolin-2-one intermediates are new compounds.

专利号:US-3941798-A
优先权日:1973-03-22
标 题 :5-Alkyl-3-(2-hydroxylamino-4-chlorophenyl)-1,3,4-oxadiazolin-2-one compounds
发明人：FORT JEAN-FRANCOIS; GIRAUDON RAYMOND
权利人:RHONE POULENC SA
摘要:Oxadiazoline derivatives of the formula: ##SPC1## n Wherein R is alkyl of 1 through 4 carbon atoms, which are useful as intermediates in the synthesis of oxadiazoline derivatives of the formula: ##SPC2## n Wherein R is as defined above and R 1 is alkyl of 1 through 4 carbon atoms, possessing useful herbicidal properties, are prepared by a process which comprises reducing the nitro group in a 5-alkyl-3-(2-nitro-4-chlorophenyl)-1,3,4-oxadiazolin of the formula: ##SPC3## n Wherein R is as defined above to a hydroxylamino group, subjecting the resulting 5-alkyl-3-(2-hydroxylamino-4-chlorophenyl)-1,3,4-oxadiazolin-2-one to the Bamberger rearrangement, and converting the amine group in the resulting 5-alkyl-3-(2-amino-4-chloro-5-hydroxyphenyl)-1,3,4-oxadiazolin-2-one to a chlorine atom. The 5-alkyl-3-(2-hydroxylamino-4-chlorophenyl)-1,3,4-oxadiazolin-2-one intermediates are compounds.

专利号:WO-9910310-A1
优先权日:1997-08-29
标 题:Process for producing diphenylethers and esters
发明人：LOURENS GERHARDUS JOHANNES
权利人:DOW CHEMICAL CO
摘要:An improved synthesis of diphenylethers, and in particular, the bacteriostat 2,4,4'-trichloro-2'-hydroxydiphenylether, is described wherein 2'-acetyl-2,4,4'-trichlorodiphenylether is oxidised under Baeyer-Villiger conditions to produce 2'-acetoxy-2,4,4'-trichlorodiphenylether in near quantitative yield. Best oxidative conditions include the use of anhydrous permaleic acid produced in situ. The ester is purified readily by simple recrystallization, as no dibenzofurans and only minor amounts of byproducts are formed in the process. The ester is converted into the desired halogenated phenolic diphenylether, 2,4,4'-trichloro-2'-hydroxydiphenylether, by hydrolysis or transesterification. The final product is purified to a high degree by vacuum distillation and crystallization to meet current purity standards for approved applications.

专利号:AU-2007276514-A1
优先权日:2006-07-15
标题:A regioselective palladium catalyzed synthesis of benzimidazoles and azabenzimidazoles