专利号:US-2025122236-A1 优先权日:2021-06-09 标题 :Intermediate for preparing fulvestrant and preparation method therefor 发明人:ZHANG FUYAO; CHEN XIANJIE 权利人:SHANGHAI BEST LINK BIOSCIENCE LLC 摘要:The invention relates to a fulvestrant intermediate and a preparation method thereof. Specifically, the invention relates to a compound shown as a formula V and a preparation method thereof, and R 1 is hydrogen or a hydroxyl protecting group. The invention also relates to a preparation method for the synthesis of fulvestrant from the compound as shown in the formula V. The method has the advantages of short reaction steps, mild and safe reaction conditions, high selectivity, simplicity and convenience in operation and purification, high synthesis efficiency and the like, and is suitable for large-scale production.
专利号:CN-116970149-A 优先权日:2023-08-01 标 题 :Preparation of conjugated porous polymer and application of conjugated porous polymer in synthesis of key intermediate of photocatalytic fulvestrant
专利号:US-7312347-B2 优先权日:2005-09-22 标题 :Substituted optically active disphosphine compound 发明人:FUJIWARA TAKAHIRO; YOKOZAWA TOHRU 权利人:TAKASAGO PERFUMERY CO LTD 摘要:Provided is a method for producing an optically active compound, in more detail, for producing an optically active compound by asymmetric hydrogenation in a high yield and asymmetric yield. The present invention also provides a catalyst for asymmetric synthesis for the above production method, especially a catalyst for asymmetric hydrogenation, containing a transition metal complex. Further, the present invention provides a new diphosphine compound useful as a ligand of the above transition metal complex and a new transition metal complex containing the above diphosphine compound. n The present invention relates to a diphosphine compound represented by the following formula (1): n na transition metal complex using the compound, a catalyst for asymmetric synthesis comprising the above transition metal complex and a method for producing an optically active compound using the above catalyst for asymmetric synthesis.
专利号:US-7893296-B2 优先权日:2002-07-30 标题:Method for producing an optically active β-amino acid 发明人:MATSUMURA KAZUHIKO; ZHANG XIAOYONG; SAITO TAKAO 权利人:TAKASAGO PERFUMERY CO LTD 摘要:Disclosed is a producing method of an optically active β-amino acid useful as intermediate for the production of medicines, agricultural. chemicals and physiologically active substances, by means of a catalytic and asymmetric synthesis method of high performance and a high enantiomeric excess, without requiring additional procedures such as introduction and removal of protecting group and so on. The method includes subjecting an enamine to an asymmetric hydrogenation.
专利号:CN-112909342-A 优先权日:2019-11-18 标 题:Synthesis method of silicon ether battery electrolyte
[参考文献]: Yusuke Ogura, Et Al. Terminal-Selective Transesterification Of Chlorine-Capped Poly(Methyl Methacrylate)S: A Modular Approach To Telechelic And Pinpoint-Functionalized Polymers. J Am Chem Soc. 2016 Apr 20;138(15):5012-5.
合成参考文献
摘要:S100 | PFASREACH | List of PFAS identified in REACH 2019 | DOI:10.5281/zenodo.7426856 摘要:S14 | KEMIPFAS | PFAS Highly Fluorinated Substances List from KEMI | DOI:10.5281/zenodo.2621524 摘要:S89 | PRORISKPFAS | List of PFAS Compiled from NORMAN SusDat | DOI:10.5281/zenodo.5769582