CAS: 21736-83-4; Spectinomycin Dihydrochloride

上下游产品

spectinomycinN,N'-(benzyloxy)carbonylspectinomycin -4(R)-dihydrospectinomycin4-O-acetyl-N,N'-(benzyloxy)carbonyl-4(R)-dihydrospectinomycin Carbonic acid (1R,2S,3R,4R,5S,6R)-2,4-bis-(benzyloxycarbonyl-methyl-amino)-6-((3aR,4S,6R,7aR)-2-methoxy-2,6-dimethyl-tetrahydro-[1,3]dioxolo[4,5-c]pyran-4-yloxy)-3,5-bis-(2,2,2-trichloro-ethoxycarbonyloxy)-cyclohexyl ester 2,2,2-trichloro-ethyl ester -4(R),4a(R)-tetrahydrospectinomycin4-O-acetyl-7,9-O-(trichloroethoxycarbonyl)-N,N'-(benzyloxy)carbonyl-4(R),4a(R)-tetrahydrospectinomycinspectinomycin free base [(1R,2R,3S,4R,5R,6S)-3-(Benzyloxycarbonyl-methyl-amino)-5-((2S,3R,4S,6R)-3,4-dihydroxy-6-methyl-tetrahydro-pyran-2-yloxy)-2,4,6-trihydroxy-cyclohexyl]-methyl-carbamic acid benzyl ester -4(R),4a(R)-tetrahydrospectinomycinN,N'-(benzyloxy)carbonyl-4(R),4a(R)-tetrahydrospectinomycin -4(R)-dihydrospectinomycinN,N'-(benzyloxy)carbonyl-4(R)-dihydrospectinomycin

N,N'-<(Benzyloxy)Carbonyl>Spectinomycin 在 Palladium On Activated Charcoal 氢气体系中,用 水,异丙醇作为反应溶剂,以90%的收率获得(+)-Spectinomycin DihydroChloride
参考文献:壮观霉素的化学:其全合成,立体控制重排和类似物
标题:壮观霉素的化学:其全合成,立体控制重排和类似物
摘要:基于区域特异性功能化和适当起始材料的操作,描述了抗生素壮观霉素的总立体控制合成.三级酮...
Doi:10.1139/V85-026

专利信息

专利号:WO-2024256370-A1
优先权日:2023-06-13
标 题 :Synthesis of glufosinate using an amidase-based process
发明人：ZIMMERMANN GUNTHER; POTT MORITZ STEFAN
权利人:BASF SE
摘要:The present invention relates to a method of preparing glufosinate, comprising the steps of hydrolysing an N-carbamoyl glufosinate amide with an Amidase enzyme to form an N- carbamoyl amino acid compound followed by cleaving off the carbamoyl moiety of said N- carbamoyl amino acid compound.

专利号:US-9693999-B2
优先权日:2011-01-26
标题:Small molecule RNase inhibitors and methods of use
发明人：DUNMAN PAUL M; OLSON PATRICK D; CHILDERS WAYNE
权利人:UNIV ROCHESTER; UNIV NEBRASKA; Temple University—Of the Commonwealth System of Higher Education
摘要:Small molecule inhibitors of bacterial ribonuclease (e.g., RnpA) and methods for their synthesis and use are described herein. The methods of using the compounds include treating and preventing microbial infections and inhibiting bacterial ribonuclease. Also described herein are methods of identifying compounds for treating or preventing a microbial infection.

专利号:US-2025120400-A1
优先权日:2021-12-10
标题:Synthesis of glufosinate using a hydantoinase-based process
发明人：DITRICH KLAUS; BREUER MICHAEL; POTT MORITZ STEFAN; ZIMMERMANN GUNTHER; SEEMAYER STEFAN
权利人:BASF SE
摘要:The present invention relates to a method of manufacturing glufosinate, comprising the steps of hydrolysing a hydantoin with a Hydantoinase enzyme to form a N-carbamoyl amino acid compound followed by cleaving off the carbamoyl moiety of said N-carbamoyl amino acid compound.

专利号:WO-2009056955-A1
优先权日:2007-10-30
标题 :Amine-bearing phospholipids (abps), their synthesis and use
发明人：ZUMBUEHL ANDREAS
权利人:UNIV BASEL; ZUMBUEHL ANDREAS
摘要:Disclosed herein are amine-bearing phospholipids (ABP). The ABPs display many properties and functionalities of naturally occurring phospholipids, but also new properties and functionalities, such as the ability to polymerize while maintaining structural integrity, that may supplement or expand the functionalities of naturally occurring phospholipids.

专利号:US-9868747-B2
优先权日:2014-02-18
标题:Marinopyrrole derivatives and methods of making and using same
发明人：LI RONGSHI; SEBTI SAID; LIU YAN; QIN YONG; SONG HAO; CHENG CHUNWEI
权利人:H LEE MOFFITT CANCER CT & RES; CHONGQING ZEIN PHARMACEUTICAL CO LTD
摘要:Marinopyrrole derivatives and methods for their synthesis and use are described herein. Novel cyclic and symmetric marinopyrroles with triazole substituents having antibacterial activity against resistant bacterial strains, such as MRSA are introduced. Also provided are methods of using the compounds for treating or preventing cancer and/or microbial infections.

专利号:US-9907753-B2
优先权日:2010-03-19
标 题 :Lipid vesicle compositions and methods of use
发明人：IRVINE DARRELL J; MOON JAEHYUN
权利人:MASSACHUSETTS INST TECHNOLOGY
摘要:The invention provides delivery systems comprised of stabilized multilamellar vesicles, as well as compositions, methods of synthesis, and methods of use thereof. The stabilized multilamellar vesicles may comprise prophylactic, therapeutic and/or diagnostic agents.