CAS: 25475-67-6; Isoquinolin-3-Amine

相似化合物

1532-84-9 1824283-75-1 1192814-93-9

上下游产品

3-chloroisoquinoline 3-bromoisoquinoline isoquinoline-3(S)-carboxamide 3-amino-4-chloroisoquinoline3-isoquinolinol 2-(Isoquinolin-3-ylaminomethylene)-malononitrile 4-(4-Bromo-phenylazo)-isoquinolin-3-ylamine 2,3-diamino-isoquinolinium 4-methylbenzenesulfonate

3-溴异喹啉置于ammonium Hydroxide,Copper(II) Sulfate体系中,化学反应生成3-氨基异喹啉
参考文献:Osborn Et Al.,Journal Of The Chemical Society,1956,P. 4191,4205
标题:Osborn Et Al.,Journal Of The Chemical Society,1956,P. 4191,4205

专利信息

专利号:US-3954771-A
优先权日:1972-06-16
标题 :Process for the preparation of 2H-3-isoquinolones
发明人：GEERTS JEAN-PIERRE JULES; LINZ RAYMOND ARMAND
权利人:UCB SA
摘要:A process for the preparation of 2H-3-isoquinolones having the formula ##SPC1## n Wherein R 1 and R 2 are each hydrogen, halogen, lower alkyl, lower alkoxy, aryl, haloaryl, alkylaryl or alkoxyaryl; R 3 and R 4 are each hydrogen, lower alkyl, lower alkoxyalkyl, lower alkenyl, lower alkynyl, cycloalkyl, aryl, aralkyl, or halo-aralkyl, which comprises cyclizing an N-formyl-2-phenyl-acetamide of the formula ##SPC2## n Wherein R 1 , R 2 , R 3 and R 4 have the same meaning as above, with a cyclodehydration agent. Said 2H-3-isoquinolones are useful as starting materials e.g. in the synthesis of 1,4-dihydro-1,4-etheno-isoquinolin-3(2H)-ones which are valuable chemotherapeutic agents in the treatment of disorders of the central nervous system, such as troubles of wakefulness, disorders of equilibrium and vertigo.

专利号:WO-9948868-A9
优先权日:1998-03-26
标 题 :Heterocyclic classes of compounds for the modulating tyrosine protein kinase
发明人：FONG ANNIE; HANNAH ALISON; HARRIS G DAVIS; HIRTH PETER; HUBBARD STEVEN R; LANGECKER PETER; LIANG CONGXIN; MCMAHON GERALD; MOHAMMADI MOOSA; SCHLESSINGER JOSEPH; SHAWVER LAURA K; SUN LI; TANG PENG C; ULLRICH AXEL
权利人:SUGEN INC; UNIV NEW YORK; MAX PLANCK INST FUR BIOCHEMIE; FONG ANNIE; HANNAH ALISON; HARRIS G DAVIS; HIRTH PETER; HUBBARD STEVEN R; LANGECKER PETER; LIANG CONGXIN; MCMAHON GERALD; MOHAMMADI MOOSA; SCHLESSINGER JOSEPH; SHAWVER LAURA K; SUN LI; TANG PENG C; ULLRICH AXEL
摘要:The invention relates to certain indolinone-based and pyrazolylamide-based compounds, their method of synthesis, and combinatorial libraries consisting of the compounds. The invention also relates to methods of modulating the function of protein kinases using these compounds and methods of treating diseases by modulating the function of protein kinases and related signal transduction pathways.

专利号:UA-77396-C2
优先权日:2000-05-09
标题 :Anthranilamides as inhibitors of kdr and flt tyrosine kinase, intermediate substances used in synthesis of anthranilamides, pharmaceutical drug and used of anthranilamides for manufacturing pharmaceuticals

专利号:ES-2773838-T3
优先权日:2012-03-07
标 题:Synthesis of polycyclic alkaloids and their use as TGR5 agonists

专利号:CN-117800909-A
优先权日:2023-12-27
标题:A kind of synthesis method of nitrogen-containing aromatic heterocyclic methylamine