CAS: 2696-84-6; 4-Propylaniline

该化合物是一种有机化合物,其特征是有一种有丙烯基替代物的阴性组(附在苯环上的氨基组),其基体位置为丙基替代体,分子式为C10H15N,表明其由十个碳原子,十五个氢原子和一个氮原子组成,该化合物一般是无色的,不粉黄液体,具有独特的类似地雷的气味.4-丙烯酰胺在有机溶剂中溶解,但由于其氢恐惧性丙基组,其溶解性有限,主要用于染料,制药和农用化学合成,该复合物可发生典型的氨基生物反应,如致癌和细胞化等,并可能由于氨基层组的电温性质而参与电刑用芳香替代.在处理4-正丙烷时,应当采取安全防范措施,因为它可能对健康造成危害,包括皮肤和呼吸刺激.

结构式图片

欧盟法规

ECHA物质C&L通报REACH预注册

上下游产品

phenylpropane 1-nitro-4-propyl-benzene 4-propylacetanilide N-propylaniline N-(4-nonyloxy-benzylidene)-4-propyl-anilineN-(4-nonyloxy-benzylidene)-4-propyl-aniline (p-propylphenyl)urea 4-n-Propylphenol N-phenyl-N'-(4-propyl-phenyl)-thioureaN-phenyl-N'-(4-propyl-phenyl)-thiourea

合成工艺路线路线简述

  • 合成目标产物 4-Propylaniline 主要起始原料 N-Propylbenzene
  • (文献来源)合成步骤主要原料 N-Propylbenzene
正丙基苯置于硫酸,硝酸体系中,化学反应生成对丙基苯胺
参考文献:Report Of The International Consensus Development Conference On Female Sexual Dysfunction: Definitions And Classifications
标题:Report Of The International Consensus Development Conference On Female Sexual Dysfunction: Definitions And Classifications
摘要:Purpose: Female Sexual Dysfunction Is Highly Prevalent But Not Well Defined Or Understood. We Evaluated And Revised Existing Definitions And Classifications Of Female Sexual Dysfunction.Materials And Methods: An Interdisciplinary Consensus Conference Panel Consisting Of 19 Experts In Female Sexual Dysfunction Selected From 5 Countries Was Convened By The Sexual Function Health Council Of The American Foundation For Urologic Disease. A Modified Delphi Method Was Used To Develop Consensus Definitions And Classifications,And Build On The Existing Framework Of The International Classification Of Diseases-10 And Dsm-Tv: Diagnostic And Statistical Manual Of Mental Disorders Of The American Psychiatric Association,Which Were Limited To Consideration Of Psychiatric Disorders.Results: Classifications Were Expanded To Include Psychogenic And Organic Causes Of Desire,Arousal,Orgasm And Sexual Pain Disorders. An Essential Element Of The New Diagnostic System Is The "Personal Distress" Criterion. In Particular,New Definitions Of Sexual Arousal And Hypoactive Sexual Desire Disorders Were Developed,And A New Category Of Noncoital Sexual Pain Disorder Was Added. In Addition,A New Subtyping System For Clinical Diagnosis Was Devised. Guidelines For Clinical End Points And Outcomes Were Proposed,And Important Research Goals And Priorities Were Identified.Conclusions: We Recommend Use Of The New Female Sexual Dysfunction Diagnostic And Classification System Based On Physiological As Well As Psychological Pathophysiologies,And A Personal Distress Criterion For Most Diagnostic Categories.
Doi:10.1016/s0022-5347(05)67828-7

海关参考信息

专利信息


专利号:WO-2012173572-A1
优先权日:2011-06-10
标 题 :Stereoselective synthesis of highly substituted enamides
发明人:PARK CHEOL-MIN; LIU YU
权利人:UNIV NANYANG TECH; PARK CHEOL-MIN; LIU YU
摘要:The disclosure provides new methods for the oxidative Heck cross-coupling reaction with electron-rich alkenes such as substituted β-amidoacrylate and other related substituted enamides. Previously, functionalization of enamides under Heck conditions has been limited to those with unsubstituted vinyl groups. By tuning the reaction parameters that allow for the balance between stability and reactivity of the reactants, the oxidative Heck cross-coupling reaction now provides highly substituted enamides in good to excellent yields. (II) (III) (I)·

专利号:WO-2009143405-A2
优先权日:2008-05-22
标 题:Synthesis of graphene sheets and nanoparticle composites comprising same

专利号:WO-0053313-A2
优先权日:1999-03-09
标 题:Lanthanide catalysts for synthesis of compounds and combinatorial libraries

专利号:US-9028800-B2
优先权日:2007-01-11
标 题 :Methods and compositions for improved F-18 labeling of proteins, peptides and other molecules
发明人:D SOUZA CHRISTOPHER A; MCBRIDE WILLIAM J; GOLDENBERG DAVID M
权利人:IMMUNOMEDICS INC
摘要:The present application discloses compositions and methods of synthesis and use of 18 F or 19 F-labeled molecules of use in PET, SPECT and/or MR imaging. Preferably, the 18 F or 19 F is conjugated to a targeting molecule by formation of a complex with a group IIIA metal and binding of the complex to a bifunctional chelating agent, which may be directly or indirectly attached to the targeting molecule. In other embodiments, the 18 F or 19 F labeled moiety may comprise a targetable construct used in combination with a bispecific antibody to target a disease-associated antigen. The disclosed methods and compositions allow the simple and reproducible labeling of molecules at very high efficiency and specific activity in 30 minutes or less. In preferred embodiments, the labeled molecule may be used for imaging in a subject without purification after labeling.

专利号:US-6417195-B1
优先权日:1999-02-22
标题 :Isoquinoline derivatives and isoquinoline combinatorial libraries
发明人:LEBL MICHAL
权利人:LION BIOSCIENCE AG
摘要:The present invention provides the synthesis of heterocyclic compounds based on the isoquinoline ring. More specifically, the invention provides novel isoquinoline derivatives as well as novel libraries comprised of such compounds.

专利号:US-5874443-A
优先权日:1995-10-19
标 题:Isoquinoline derivatives and isoquinoline combinatorial libraries
发明人:KIELY JOHN S; GRIFFITH MICHAEL C
权利人:TREGA BIOSCIENCES INC
摘要:The present invention provides the synthesis of heterocyclic compounds based on the isoquinoline ring. More specifically, the invention provides novel isoquinolines as well as novel libraries comprised of many such compounds, and methods of synthesizing the libraries.
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合成参考文献


摘要:Journal of Medicinal Chemistry., 17(900), 1974
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