CAS: 51582-41-3; 2-(4-(Benzyloxy)-3-Nitrophenyl)Oxirane

该化合物是一种有机化合物,其特征是其环氧功能组,即三者组成的环醚;该化合物的特征是硝基化合物组和联苯环上的苯甲基苯氧替代体,有助于其化学反应和有机合成的潜在应用;该硝基苯组的存在通常会增强芳香系统的电光特性,使其对核素更具反应性;该氧气结构表明,它可以参与环开反应,这在各种化学变异中具有重大意义;此外,该化合物的苯氧基组可能影响其溶解性和与生物系统的互动.

英文名称2-(4-(Benzyloxy)-3-Nitrophenyl)Oxirane
中文名称2-(4-(苄氧基)-3-硝基苯基)环氧乙烷
IUPAC名称2-(4-(benzyloxy)-3-nitrophenyl)oxirane
其它别名3-硝基-4-(苯甲氧基)苯基环氧乙烷; 4-Benzyloxy-3-Nitro-Styrenoxide
CAS编号51582-41-3
MFCD编号:MFCD07782084
EINECS号:610-702-4
分子式:C15H13NO4
分子量:271.27
产品CID: 1505652
产品分类有机原料→分子砌块→芳环类化合物→苯类化合物

相似结构搜索
InChIKey: MOGUBMMGIJLRHQ-UHFFFAOYSA-N
InChI=1/C15H13NO4/c17-16(18)13-8-12(15-10-20-15)6-7-14(13)19-9-11-4-2-1-3-5-11/h1-8,15H,9-10H2…
计算化学: 氢键受体数4.0氢键供体数0.0可旋转键数5.0

相似化合物

14347-05-8 43229-01-2 188690-82-6

MSDS等安全信息

GHS象形图
GHS符号GHS08;
注释: Health hazard
危险类别呼吸道致敏类别1
皮肤致敏类别1
警示词Danger(危险)
危险描述H334 |吸入可能引起过敏或哮喘症状或呼吸困难.
H317 |可能引起皮肤过敏反应.
防范说明P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501
危险品标志Xi

欧盟法规

ECHA物质C&L通报REACH预注册

上下游产品

CAS号43229-01-2 3'-硝基-4'-苄氧基-2-溴苯乙酮 | CAS号6322-56-1 4'-羟基-3'-硝基苯乙酮 | CAS号14347-05-8 4-苄氧基-3-硝基苯乙酮 | CAS号99-93-4 对羟基苯乙酮 | CAS号515152-69-9 4-ethenyl-2-nit...

合成工艺路线路线简述

3'-硝基-4'-苄氧基-2-溴苯乙酮置于sodium Tetrahydroborate体系中,用甲醇作为反应溶剂,化学反应 3.0H,反应生成 1-(4-苄氧基-3-硝基)苯基环氧乙烷
参考文献:Mereyala,Hari Babu; Sambaru,Kalyani,Indian Journal Of Chemistry-Section B Organic And Medicinal Chemistry,2005,Vol. 44,# 1,P. 167-169
标题:Mereyala,Hari Babu; Sambaru,Kalyani,Indian Journal Of Chemistry-Section B Organic And Medicinal Chemistry,2005,Vol. 44,# 1,P. 167-169

海关参考信息

2902600000-乙苯
2906210000-苄醇
2910100000-环氧乙烷
2908199090-其他酚的卤化衍生物
💡 提示：海关信息按照顺序优先匹配，如需确认的海关信息，请参考相关资料。
详情请参考：📖 海关编码查询和海关进出口税则

专利信息

专利号:US-9029421-B2
优先权日:2008-06-02
标题 :Process for the synthesis of arformoterol
发明人：HALDAVANEKAR VAISHALI VAMAN; PRABHU MANGESH; RAO DHARMARAJ RAMACHANDRA; KANKAN RAJENDRA NARAYANRAO
权利人:HALDAVANEKAR VAISHALI VAMAN; PRABHU MANGESH; RAO DHARMARAJ RAMACHANDRA; KANKAN RAJENDRA NARAYANRAO; CIPLA LTD
摘要:The present invention provides a process for preparing a compound of formula (VI) or a salt thereof, the process comprising: (i) reacting 4-methoxyphenyl acetone with an amine of formula (VIII) under conditions of reductive amination to produce a compound of formula (II) or a salt thereof, wherein there is no isolation of an imine intermediate formed during the reductive amination; (ii) condensing the compound (II) or the acid addition salt thereof with an Î±-haloketone of formula (III) to produce the compound of formula (IV); (iii) reducing the compound (IV) to a compound of formula (V); and (iv) reducing the compound (V) to the compound of formula (VI), wherein the reduction is carried out in the presence of either (1) a hydrogen donating compound in the presence of a hydrogen transfer catalyst; or (2) ammonium formate using a hydrogenation catalyst, wherein R 1 and R 2 are independently optionally substituted arylalkyl, and Hal is selected from chloro or bromo.

专利号:US-2015210629-A1
优先权日:2008-06-02
标题 :Process for the Synthesis of Arformoterol

专利号:RU-2079486-C1
优先权日:1990-09-26
标题 :Method for synthesis of formoterol or its derivatives

专利号:KR-20110015449-A
优先权日:2008-06-02
标题:Process for the synthesis of arformoterol

专利号:EP-2285770-B1
优先权日:2008-06-02
标题 :Process for the synthesis of arformoterol

专利号:EP-2285770-A1
优先权日:2008-06-02
标题 :Process for the synthesis of arformoterol