CAS: 70201-43-3; 3-Bromoisonicotinaldehyde

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3-Bromo-4-(Dibromomethyl)Pyridine置于氢溴酸,Silver Nitrate体系中,用 水 作为反应溶剂,化学反应 0.5H,反应生成 3-溴吡啶-4-醛
参考文献: Thieno[3,2-D]Pyrimidine-6-Carboxamides And Analogues As Sirtuin Modulators[fr] Thiéno[3,2-D]Pyrimidine-6-Carboxamides Et Analogues Comme Modulateur De Sirtuine
标题: Thieno[3,2-D]Pyrimidine-6-Carboxamides And Analogues As Sirtuin Modulators[fr] Thiéno[3,2-D]Pyrimidine-6-Carboxamides Et Analogues Comme Modulateur De Sirtuine
摘要:本文提供了新颖的替代噻吩[3,2-D]嘧啶-6-羧酰胺sirtuin抑制剂及其使用方法.这些sirtuin抑制剂可用于抑制sirtuin介导的生物过程,例如用于治疗和/或预防包括但不限于癌症,神经退行性疾病和炎症在内的疾病和疾患.本文还提供了包含这些sirtuin抑制剂的药物组合物以及包含sirtuin抑制剂与另一种治疗药剂组合的组合物.

专利信息

专利号:CN-113649067-B
优先权日:2021-08-13
标题:A kind of organic photocatalyst, preparation method and its application in the synthesis of 2,3,5-trimethylhydroquinone diester

专利号:US-9745253-B2
优先权日:2015-03-13
标 题 :Alpha-cinnamide compounds and compositions as HDAC8 inhibitors
发明人：BAIR KENNETH W; Barczak Nicholas; HAN BINGSONG; LANCIA JR DAVID R; LIU CUIXIAN; MARTIN MATTHEW W; NG PUI YEE; Rudnitskaya Aleksandra; THOMASON JENNIFER R; ZABLOCKI MARY MARGARET; ZHENG XIAOZHANG
权利人:FORMA THERAPEUTICS INC
摘要:The present invention relates to inhibitors of histone deacetylases, in particular HDAC8, that are useful for the treatment of cancer and other diseases and disorders, as well as the synthesis and applications of said inhibitors.