CAS: 76006-33-2; 3-Bromo-2-Methylbenzoic Acid

上下游产品

CAS号124-38-9 二氧化碳 | CAS号69321-60-4 2,6-二溴甲苯 | CAS号118-90-1 邻甲基苯甲酸 | CAS号52780-15-1 3-溴-2-甲基苯甲腈 | CAS号99-99-0 对硝基甲苯 | CAS号76006-32-1 1-(2-(3-bromo-2... | CAS号337536-14-8 3-溴-2-溴甲基苯甲酸甲酯 | CAS号337536-15-9 4-溴异吲哚啉-1-酮 | CAS号52780-15-1 3-溴-2-甲基苯甲腈 | CAS号21900-41-4 5-溴-2-甲氧基苄氯 | CAS号99548-54-6 2-甲基-3-溴苯甲酸甲酯 | CAS号79669-50-4 2-甲基-5-溴苯甲酸甲酯 | CAS号955929-54-1 2-甲基-3-(4,4,5,5... | CAS号27060-75-9 2-溴-5-甲氧基甲苯 | CAS号765948-78-5 4-(4,4,5,5-四甲基-... | CAS号103038-43-3 3-溴-2-甲基苯甲酸乙酯

对甲苯甲酸置于铁粉 溴,乙醇体系中,用 二氯甲烷 作为反应溶剂,化学反应 0.67H,反应生成 3-溴-2-甲基苯甲酸
参考文献:Methods Of Producing C-Aryl Glucoside Sglt2 Inhibitors
标题:Methods Of Producing C-Aryl Glucoside Sglt2 Inhibitors
摘要:用于生产治疗糖尿病和相关疾病的c-芳基葡萄糖苷sglt2抑制剂的方法,以及其中间体.c-芳基葡萄糖苷可以与氨基酸复合物形成试剂形成复合物.

专利信息

专利号:US-8188113-B2
优先权日:2006-09-14
标 题 :Dihydropyridopyrimidinyl, dihydronaphthyidinyl and related compounds useful as kinase inhibitors for the treatment of proliferative diseases
发明人：FLYNN DANIEL L; PETILLO PETER A; KAUFMAN MICHAEL D; PATT WILLIAM C
权利人:FLYNN DANIEL L; PETILLO PETER A; KAUFMAN MICHAEL D; PATT WILLIAM C; DECIPHERA PHARMACEUTICALS INC
摘要:The present invention relates to novel dihydropyridopyrimidinyl, dihydronaphthyridinyl, and related compounds which are kinase inhibitors and modulator useful for the treatment of various diseases. More particularly, the invention is concerned with such compounds, kinase/compound adducts, methods of treating diseases, and methods of synthesis of the compounds. Preferably, the compounds are useful for the modulation of kinase activity of Raf kinases and disease polymorphs thereof. Compounds of the present invention find utility in the treatment of mammalian cancers and especially human cancers including but not limited to malignant melanoma, colorectal cancer, ovarian cancer, papillary thyroid carcinoma, non small cell lung cancer, and mesothelioma. Compounds of the present invention also find utility in the treatment of rheumatoid arthritis and retinopathies including diabetic retinal neuropathy and macular degeneration.

专利号:US-11299484-B2
优先权日:2018-10-10
标 题 :Inhibiting fatty acid synthase (FASN)
发明人：MARTIN MATTHEW W; ZABLOCKI MARY-MARGARET; MENTE SCOT; DINSMORE CHRISTOPHER; WANG ZHONGGUO; ZHENG XIAOZHANG
权利人:FORMA THERAPEUTICS INC
摘要:The present disclosure is directed to inhibitors of FASN. The compounds can be useful in the treatment of disease or disorders associated with the inhibition of FASN. For instance, the disclosure is concerned with compounds and compositions for inhibition of FASN, methods of treating, preventing, or ameliorating diseases or disorders associated with the inhibition of FASN, and methods of synthesis of these compounds.

专利号:CN-108997368-A
优先权日:2018-06-29
标题 :A method for the efficient synthesis of optically active multi-substituted 2,3-dihydrobenzofuran compounds catalyzed by an asymmetric organophosphine

专利号:CN-116813508-A
优先权日:2022-03-21
标 题 :Method for highly selective synthesis of 5-halo-2-methylbenzoic acid

专利号:US-6090912-A
优先权日:1993-05-27
标 题:Topologically segregated, encoded solid phase libraries comprising linkers having an enzymatically susceptible bond
发明人：LEBL MICHAL; LAM KIT S; SALMON SYDNEY E; KRCHNAK VICTOR; SEPETOV NIKOLAI; KOCIS PETER
权利人:SELECTIDE CORP
摘要:The invention relates to libraries of synthetic test compound attached to separate phase synthesis supports. In particular, the invention relates to libraries of synthetic test compound attached to separate phase synthesis supports that also contain coding molecules that encode the structure of the synthetic test compound. The molecules may be polymers or multiple nonpolymeric molecules. Each of the solid phase synthesis support beads contains a single type of synthetic test compound. The synthetic test compound can have backbone structures with linkages such as amide, urea, carbamate (i.e., urethane), ester, amino, sulfide, disulfide, or carbon-carbon, such as alkane and alkene, or any combination thereof. Examples of subunits suited for the different linkage chemistries are provided. The synthetic test compound can also be molecular scaffolds, such as derivatives of monocyclic of bicyclic carbohydrates, steroids, sugars, heterocyclic structures, polyaromatic structures, or other structures capable of acting as a scaffolding. Examples of suitable molecular scaffolds are provided. The invention also relates to methods of synthesizing such libraries and the use of such libraries to identify and characterize molecules of interest from among the library of synthetic test compound.

专利号:CN-109678787-A
优先权日:2018-12-31
标 题 :A kind of new HCV virus NS3/4A inhibitor synthesis intermediate and synthesis method