CAS: 14452-30-3; 1-(3-Iodophenyl)Ethanone

相似化合物

13329-40-3 1003712-14-8 170282-53-8

上下游产品

CAS号99-03-6 3'-氨基苯乙酮 | CAS号98-86-2 苯乙酮 | CAS号99-93-4 对羟基苯乙酮 | CAS号135774-37-7 α-(benzoyloxy)-... | CAS号75-16-1 甲基溴化镁 | CAS号618-51-9 间碘苯甲酸 | CAS号3609-53-8 对乙酰基苯甲酸乙酯 | CAS号20731-95-7 2-羟基-2-苯基丙酸甲酯 | CAS号98-86-2 苯乙酮 | CAS号32852-92-9 间苯氧基苯乙酮 | CAS号6136-68-1 3-乙酰苄腈 | CAS号618-51-9 间碘苯甲酸 | CAS号66067-44-5 3-乙酰苯甲酮 | CAS号133910-11-9 (1R,3S,5Z)-5-[(... | CAS号3112-01-4 1-([1,1'-联苯]-3-基)乙酮 | CAS号121-71-1 3-羟基苯乙酮

间氨基苯乙酮置于对甲苯磺酸,Sodium Iodide体系中,用 水,乙腈 用作溶剂,化学反应 2.0H,以64%的收率获得3-碘苯乙酮
参考文献:使用一锅法从芳基胺中进行生物活性剂的后期碘化†
标题:使用一锅法从芳基胺中进行生物活性剂的后期碘化†
摘要:已经开发了一种简单有效的一锅串联程序,该程序通过稳定的重氮盐从容易获得的芳基胺生成芳基碘化物.操作简单的程序和温和的条件允许对各种带有各种官能团和取代方式的芳基化合物进行后期碘化.还开发了一种新颖的合成策略,包括制备硝基芳基化合物,然后还原化学选择性的二氯化锡(II)以及使用一锅重氮化-碘化转化反应.通过制备许多具有医学重要性的化合物,包括cns1261(一种n-甲基-D的spect显像剂),证明了该方法的普遍适用性.-天冬氨酸(nmda)受体和ibox,一种用于检测大脑淀粉样斑块的化合物.
Doi:10.1039/c7Ra11860K

专利信息

专利号:WO-0009116-A1
优先权日:1998-08-14
标 题:Grp receptor ligands
发明人：XIANG JIA-NING; KARPINSKI JOSEPH M; CHRISTENSEN SIEGFRIED B IV
权利人:SMITHKLINE BEECHAM CORP; XIANG JIA NING; KARPINSKI JOSEPH M; CHRISTENSEN SIEGFRIED B IV
摘要:Novel GRP receptor antagonists are provided. Methods of using the present compounds to antagonize GRP receptors are also provided. The present invention further involves the synthesis of the present compounds.

专利号:US-2023002426-A1
优先权日:2019-11-15
标题 :Chiral synthesis of a tertiary alcohol

专利号:WO-0009115-A1
优先权日:1998-08-14
标 题 :Grp receptor ligands
发明人：XIANG JIA-NING; OSIFO IRENNEGBE KELLY; KARPINSKI JOSEPH M; CHRISTENSEN SIEGFRIED B IV
权利人:SMITHKLINE BEECHAM CORP; XIANG JIA NING; OSIFO IRENNEGBE KELLY; KARPINSKI JOSEPH M; CHRISTENSEN SIEGFRIED B IV
摘要:Novel GRP receptor antagonists are provided. Methods of using the present compounds to antagonize GRP receptors are also provided. The present invention further involves the synthesis of the present compounds.

专利号:WO-2021097139-A1
优先权日:2019-11-15
标 题 :Chiral synthesis of a tertiary alcohol

专利号:CN-113372184-A
优先权日:2021-03-26
标 题 :A method for the synthesis of C–N-axis chiral phenanthridines based on a chirality transfer strategy

专利号:CN-116874400-A
优先权日:2023-06-09
标题 :Synthesis method of chiral alpha-aryl thioester