Alkaline Earth Salt Of/the/ Methylsulfuric Acid置于盐酸,Amalgamated Zinc,溶剂黄146体系中,化学反应生成4-丁基苯酚 参考文献:Pigment Epithelial Detachment In The Elderly 标题:Pigment Epithelial Detachment In The Elderly 摘要:Background: A Prospective Analysis Was Performed To Characterize The Angiographic Appearance,Natural Course And Prognosis Of Serous Pigment Epithelial Detachments (Peds) In Elderly Patients. The Aim Was To Differentiate Peds According To Their Angiographic Characteristics And To Analyze The Specific Clinical,Visual And Morphologic Course Of The Different Peds. Methods: Fluorescein And Indocyanine Green Angiography Were Performed In 10 1 Consecutive Patients (53-87 Years; 63 Female,38 Male) With Clinical Signs Of Serous Ped And Drusen. Results: Different Types Of Serous Ped Were Identified: Polypoidal Choroidal Vasculopathy (Pcv)-Associated Ped In 14 Patients (13.9%),Vascular Ped In 72 (71.2%),And Avascular Ped In 15 (14.9%). All Peds Resulted Initially In Similar Visual Loss. Avascular Peds Were Smaller Than Vascular Peds,And The Latter Were Smaller Than Pcv-Peds. During Follow-Up These Differences Were Always Present,But All Peds Enlarged Initially Followed By Regression. This Course Was Associated In All Peds With Progressive Visual Loss,Accompanied By The Development Of Rpe Atrophy In Avascular Peds Or Disciform Scars Or Rpe Tears In The Two Other Types. Conclusion: Despite Different Associations,All Peds Have A Similar Clinical Course With Respect To Visual Loss And Enlargement Or Regression. This Is Compatible With The Proposed Common Pathogenetic Background With A Hydrophobic Barrier In Bruch'S Membrane Causing Fluid Resulting From Rpe Pumping Activity To Accumulate Between The Pigment Epithelium And Bruch'S Membrane. Doi:10.1007/s00417-002-0505-8
专利号:US-2015336866-A1 优先权日:2013-01-01 标题:Synthesis of difluoromethyl ethers and sulfides 发明人:HARTWIG JOHN; FIER PATRICK 权利人:UNIV CALIFORNIA 摘要:The synthesis of difluoromethyl ethers and sulfides with a simple, non-ozone-depleting reagent is described. The difluoromethylation of phenols with this reagent occurs at room temperature within minutes with exceptional functional group tolerance. The mild conditions makes possible tandem processes for the conversion of aryl boronic acids, aryl halides and arenes to difluoromethyl ethers. Mechanistic studies support a reaction pathway involving nucleophilic attack of the phenolate to difluorocarbene.
专利号:US-4939112-A 优先权日:1988-10-06 标 题:Catalyst for synthesis of vesicular phenoxy resins 发明人:BENNETT EVERETT W 权利人:JAMES RIVER PAPER CO 摘要:A catalyst for synthesis of vesicular phenoxy resins is disclosed. The catalyst includes a water-insoluble complex of a hydric phenol and a quaternary ammonium or phosphonium salt of the hydric phenol. Preferably, the hydric phenol is an intermediate of the phenoxy resin being produced. Dihydric phenols, such as sulfonyldiphenol are preferred. The invention further relates to a reaction medium for polymerization of phenoxy resins including the above-described catalyst and a solvent medium capable of dissolving the phenoxy resins and otherwise not interfering with the polymerization reaction. The solvent medium is advantageously free of toxic Methyl Cellosolve.
专利号:US-4092351-A 优先权日:1976-02-17 标 题 :Method of synthesis of 4,5,6-trihydroxyisophthalic acid 发明人:SHIPCHANDLER MOHAMMED T 权利人:IMC CHEMICAL GROUP 摘要:A process for the synthesis of 4,5,6-trihydroxyisophthalic acid by reacting dialkyl glutarate with dialkyl dialkoxymalonate.
专利号:US-4046817-A 优先权日:1974-07-19 标题 :Method of synthesis of pyrogallol 发明人:SHIPCHANDLER MOHAMMED T 权利人:IMC CHEMICAL GROUP 摘要:A process for the synthesis of pyrogallol from glutaric ester and dialkoxymalonic ester.
专利号:US-6342582-B1 优先权日:1989-12-04 标 题 :Reaction and dissolving medium for peptides and synthesis method using this medium 发明人:GALVEZ MARIE; MAURICE MARIE-FRANCE 权利人:RHODIA CHIMIE SA 摘要:The present invention relates to a reaction and dissolving medium for the synthesis of peptides. This reaction and dissolving medium for peptide synthesis and/or purification comprises a diluent A chosen from a group of water-immiscible solvents and a phenol B. By employing this reaction and dissolving medium, peptides can be synthesized which are useful as medicaments, vaccines, agro-foodstuff products or plant protection products.
专利号:US-4161609-A 优先权日:1977-09-14 标题:Synthesis of carboxylic acid esters 发明人:CRAMER RICHARD D 权利人:DU PONT 摘要:A method is provided for converting a carboxylic acid amide to a carboxylic acid ester by reacting a vaporized mixture of the amide and an aliphatic alcohol or a phenol in the presence of a suitable catalyst at temperatures of from 100 DEG C. to 400 DEG C. The process is especially useful for the conversion of methacrylamide to methyl methacrylate.
摘要:Ishii, A., Science of Synthesis Knowledge Updates, (2016) 2, 371. 摘要:Barsegyan, Y. A.; Vil’, V. A.; Tomkinson, N. C. O.; Terent’ev, A. O., Science of Synthesis Knowledge Updates, (2022) 1, 242. 摘要:Ewing, T. A.; Fraaije, M. W.; van Berkel, W. J. H., Science of Synthesis: Biocatalysis in Organic Synthesis, (2015) 3, 165. 摘要:S109 | PARCEDC | List of 7074 potential endocrine disrupting compounds (EDCs) by PARC T4.2 | DOI:10.5281/zenodo.10944198 摘要:Zhu, H.; Fan, Q., Science of Synthesis: Knowledge Updates, (2024) 3, 372.