CAS: 2393-17-1; 3-(4-Aminophenyl)Propionic Acid

该化合物是一种有机化合物,其特点是氨基酸和碳本酸功能组,其特点是附于一个苯环的丙基酸链,其位置为氨基基;这一结构既具有水利特性,又具有水利特性,也具有疏水利特性,在极地溶剂中溶解,同时保持一些脂质;该化合物一般是白色的,以其在药物中的潜在用途而著称,特别是作为各种生物活性化合物合成的中间体;该化合物的氨基组可参与氢的结合,影响其再活性和生物系统中的相互作用;此外,由于存在氨基酸组,可以形成盐类和酯类,从而进一步扩大其在化学合成中的效用;安全数据表明,如同许多氨基和箱酸一样,应当谨慎处理,因为它在与皮肤或眼睛接触时可能造成刺激.

结构式图片

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CAS号16642-79-8 3-(4-硝基苯基)丙酸 | CAS号882-06-4 (E)-4-硝基肉桂酸 | CAS号30980-75-7 p-azid°Cinnamic acid | CAS号619-89-6 4-硝基肉桂酸 | CAS号2393-18-2 4-胺桂皮酸 | CAS号10034-85-2 氢碘酸 | CAS号501-97-3 对羟基苯丙酸 | CAS号99-96-7 4-羟基苯甲酸 | CAS号30132-20-8 3-(2-Amino-benz... | CAS号885101-89-3 4-[[(3-苯氧苯基)甲基]... | CAS号103489-31-2 3-(4-叠氮苯基)丙酸 | CAS号35418-07-6 3-(4-氨基苯基)丙酸甲酯 | CAS号14572-92-0 4-氨基苯丙醇 | CAS号149506-05-8 3-(4-叔丁氧基羰基氨基-苯基)丙酸 | CAS号2019-34-3 3-(4-氯苯基)丙酸 | CAS号882847-07-6 3-(4-((((9H-芴-9...

合成工艺路线路线简述

    对硝基肉桂酸置于palladium 10% On Activated Carbon,氢气体系中,用 甲醇 用作溶剂,55.0 °C,101.33 Kpa 条件下,反应 4.0H,以95%的收率获得3-(4-氨基苯基)丙酸
    参考文献:该mri信号的正变化通过一个c-2官能β环糊精的分子内包合配合†
    标题:该mri信号的正变化通过一个c-2官能β环糊精的分子内包合配合†
    摘要:据报道合成了一种新的基于β-环糊精支架的造影剂,该支架在其次要面上带有柔性的亲脂性间隔臂.已知分子间宿主-客体包涵体复合物会增强对比成像.我们将此概念扩展到分子内复合.使用氢肉桂酸和金刚烷羧酸作为外部客体,通过NMR光谱,圆二色性和磁共振成像比较了分子间和分子内的相互作用.观测到的弛豫度的这种正向变化是旨在开发智能分子mri探针的新策略的关键要素.
    Doi:10.1039/c6Ob02583H

    海关参考信息

    专利信息


    专利号:US-9206222-B2
    优先权日:2009-06-29
    标题:Solid phase peptide synthesis of peptide alcohols
    发明人:CAUSSIL-AMBLARD MURIEL; MARTINEZ JEAN; TAILHADES JULIEN
    权利人:CAUSSIL-AMBLARD MURIEL; MARTINEZ JEAN; TAILHADES JULIEN; CENTRE NAT RECH SCIENT
    摘要:The present invention relates to the synthesis of depsipeptides on solid phase support. Said depsipeptides are then implicated in a solution phase O—N acyl shift enabling to obtain the corresponding peptide alcohols.

    专利号:US-5527824-A
    优先权日:1985-07-22
    标题 :Substituted Di-T-Butlyphenols useful for inhibiting leukotriene synthesis
    发明人:SCHERRER ROBERT A
    权利人:RIKER LABORATORIES INC
    摘要:Substituted Di-T-Butylphenols useful for inhibiting the synthesis of leukotrienes are disclosed.

    专利号:US-8546533-B2
    优先权日:2008-08-29
    标 题:Pipecolic linker and its use for chemistry on solid support
    发明人:MARTINEZ JEAN; ZAJDEL PAWEL; PAWLOWSKI MACIEJ; SUBRA GILLES
    权利人:MARTINEZ JEAN; ZAJDEL PAWEL; PAWLOWSKI MACIEJ; SUBRA GILLES; CENTRE NAT RECH SCIENT; UNIV MONTPELLIER 1; UNIV JAGELLONE; UNIV MONTPELLIER II
    摘要:The present invention relates to a pipecolic linker and its use as a solid-phase linker in organic synthesis. Said pipecolic solid-phase linker may be used for coupling functional groups chosen between primary amines, secondary amines, aromatic amines, alcohols, phenols and thiols. In particular, said pipecolic solid-phase linker may be used for peptide or pseudopeptide synthesis, such as the reverse N to C peptide synthesis or the retro-inverso peptide synthesis, or for the synthesis of small organic molecules.

    专利号:US-2023295613-A1
    优先权日:2020-02-14
    标 题:Long chain carbon and cyclic amino acids substrates for genetic code reprogramming
    发明人:JEWETT MICHAEL C; LEE JOONGOO; MOORE JEFFREY S; SCHWARZ KEVIN J
    权利人:UNIV NORTHWESTERN; UNIV ILLINOIS
    摘要:Abstract: Disclosed are methods, systems, components, and compositions for synthesis of sequence defined polymers. The methods, systems, components, and compositions may be utilized for incorporating novel substrates that include non-standard amino acid monomers and non-amino acid monomers into sequence defined polymers. As disclosed herein, the novel substrates may be utilized for acylation of tRNA via flexizyme catalyzed reactions. The tRNAs thus acylated with the novel substrates may be utilized in synthesis platforms for incorporating the novel substrates into a sequence defined polymer.

    专利号:US-11814621-B2
    优先权日:2018-06-01
    标题 :Expanding the chemical substrates for genetic code reprogramming
    发明人:JEWETT MICHAEL CHRISTOPHER; LEE JOONGOO; MOORE JEFFREY S; SCHWIETER KENNETH E; SCHWARZ KEVIN JEROME
    权利人:UNIV NORTHWESTERN; UNIV ILLINOIS
    摘要:Disclosed are methods, systems, components, and compositions for synthesis of sequence defined polymers. The methods, systems, components, and compositions may be utilized for incorporating novel substrates that include non-standard amino acid monomers and non-amino acid monomers into sequence defined polymers. As disclosed herein, the novel substrates may be utilized for acylation of tRNA via flexizyme catalyzed reactions. The tRNAs thus acylated with the novel substrates may be utilized in synthesis platforms for incorporating the novel substrates into a sequence defined polymer.

    专利号:WO-2011000848-A1
    优先权日:2009-06-29
    标题 :Solid phase peptide synthesis of peptide alcohols
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    合成参考文献


    摘要:S55 | ZINC15PHARMA | Pharmaceuticals from ZINC15 | DOI:10.5281/zenodo.3247749
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