CAS: 4707-95-3; Tert-Butyldichlorophosphine Oxide Tert-Butylphosphonyl Dichloride

上下游产品

CAS号507-20-0 氯代叔丁烷 | CAS号513-36-0 氯代异丁烷 | CAS号75-28-5 异丁烷 | CAS号25979-07-1 叔丁基二氯化膦 | CAS号27843-27-2 1-Butene,2-chlo... | CAS号115-11-7 2-甲基丙烯 | CAS号7719-12-2 三氯化磷 | CAS号4923-84-6 叔丁基磷酸 | CAS号21187-18-8 TERT-BUTYLPHOSP... | CAS号34250-35-6 2-[chloro(metho... | CAS号15572-56-2 异丙胺盐酸盐 | CAS号600116-15-2 tBuPO(NHiPr)2 | CAS号754-24-5 2-difluorophosp... | CAS号677-76-9 ditert-butylpho... | CAS号684-19-5 二叔丁基氧化磷

氯代叔丁烷置于三氯化铝,三氯化磷,盐酸,水体系中,用 二氯甲烷,氯仿 作为反应溶剂,化学反应生成 叔丁基二氯磷酸
参考文献:非对映选择性钴介导的[2 + 2 + 2]取代的线性烯二炔氧化膦的环加成反应:范围和限制.
标题:非对映选择性钴介导的[2 + 2 + 2]取代的线性烯二炔氧化膦的环加成反应:范围和限制.
摘要:制备了在末端或内部位置均具有双键并且将氧化膦附接至炔烃或烯烃末端的各种取代的线性烯二炔膦氧化物.他们的钴(i)介导的环化以高收率生产出eta(4)络合的三环化合物.内/外选择性取决于烯二炔上氧化膦的位置和系链中双键的位置.对于手性氧化膦,观测到一定程度的诱导,并且取决于磷原子上的取代基,非对映选择性可以达到74%.迄今为止,这是报道的建立立体反应生成中心的环化反应的最高水平.关于我们所有的结果,
DOI:10.1021/jo026212R

专利信息

专利号:US-2015099864-A1
优先权日:2013-10-08
标题:Preparation of organophosphate peptide adducts
发明人：BREWER BOBBY N; LUCAS ERIC A; BURKITT NATHAN T
权利人:BATTELLE MEMORIAL INSTITUTE
摘要:Disclosed are methods for the synthesis of organophosphorus-adducted peptides. Such peptides may be useful as biomarkers of organophosphate exposure, or for the synthesis of antibodies. Also disclosed are peptide adducts including peptide adducts of tabun, and aged adducts.

专利号:WO-2015053980-A1
优先权日:2013-10-08
标 题 :Preparation of organophosphate peptide adducts
发明人：BREWER BOBBY N; LUCAS ERIC A; BURKITT NATHAN T
权利人:BATTELLE MEMORIAL INSTITUTE
摘要:Disclosed are methods for the synthesis of organophosphorus-adducted peptides. Such peptides may be useful as biomarkers of organophosphate exposure, or for the synthesis of antibodies. Also disclosed are peptide adducts including peptide adducts of tabun, and aged adducts.