CAS: 96990-18-0; (2S,3S,4S,5R,6R)-6-(((3S,4Ar,6Ar,6Bs,8As,12As,14Ar,14Br)-8A-Carboxy-4,4,6A,6B,11,11,14B-Heptamethyl-1,2,3,4,4A,5,6,6A,6B,7,8,8A,9,10,11,12,12A,14,14A,14B-Icosahydropicen-3-yl)Oxy)-3,5-Dihydroxy-4-(((2S,3R,4S,5R)-3,4,5-Trihydroxytetrahydro-2H-Pyran-2-yl)Ox

该化合物是来自苦瓜(Momordica chrantia)等自然来源的三叶杆状沙邦因化合物,具有显著的生物活性,包括潜在的抗炎,抗病毒和抗直肠特性.该化合物的特点是独特的淋巴菌结构,有助于其与生物目标的选择性互动.Momordin Ic通常用于药理研究,以适应细胞路径,特别是涉及多功能性病和免疫反应的路径.其高纯度和稳定性使其适合分析和实验应用.研究人员认为Momordin Ic在研究天然产品衍生物及其治疗机制时具有再生性.

英文名称(2S,3S,4S,5R,6R)-6-(((3S,4Ar,6Ar,6Bs,8As,12As,14Ar,14Br)-8A-Carboxy-4,4,6A,6B,11,11,14B-Heptamethyl-1,2,3,4,4A,5,6,6A,6B,7,8,8A,9,10,11,12,12A,14,14A,14B-Icosahydropicen-3-yl)Oxy)-3,5-Dihydroxy-4-(((2S,3R,4S,5R)-3,4,5-Trihydroxytetrahydro-2H-Pyran-2-yl)Ox
中文名称地肤子皂苷 Ic
IUPAC名称(2S,3S,4S,5R,6R)-6-(((3S,4aR,6aR,6bS,8aS,12aS,14aR,14bR)-8a-carboxy-4,4,6a,6b,11,11,14b-heptamethyl-1,2,3,4,4a,5,6,6a,6b,7,8,8a,9,10,11,12,12a,14,14a,14b-icosahydropicen-3-yl)oxy)-3,5-dihydroxy-4-(((2S,3R,4S,5R)-3,4,5-trihydroxytetrahydro-2H-pyran-2-yl)oxy)tetrahydro-2H-pyran-2-carboxylic acid
其它别名28-Noroleanane,b-D-glucopyranosiduronic acidderiv.; Momordin Ic
CAS编号96990-18-0
MFCD编号:MFCD11042256
分子式:C41H64O13
分子量:764.95
产品CID: 2019644
产品分类生物化工 → 提取物

相似结构搜索
产品信息参考
InChIKey: HWYBGIDROCYPOE-WEAQAMGWSA-N
HWYBGIDR°CYPOE-UAEHAXNUNA-N…
计算化学: 氢键受体数13.0氢键供体数7.0可旋转键数6.0

物理性质

熔点238-240 °C
沸点886.2±65.0 °C at 760 mmHg
闪点263.1±27.8 °C
密度1.4±0.1 g/cm3
pKa:2.75±0.70(预测)
PSA:212.67
LogP:9.87
折射率1.606
蒸汽压0.0±0.6 mmHg at 25°C
溶解性Methanol (Slightly, Heated, Sonicated), Pyridine (Slightly)
外观形态白色至淡黄色固体
储存条件2-8°C
产品应用该化合物用于抗癌剂,并用PI3K和MAPK路径依赖方式诱发HEPG2流感.

上下游产品

CAS号508-02-1 齐墩果酸 | CAS号26020-14-4 金盏花苷E

合成工艺路线路线简述

(2S,3S,4S,5R,6R)-6-[[(3S,4Ar,6Ar,6Bs,8As,12As,14Ar,14Br)-4,4,6A,6B,11,11,14B-Heptamethyl-8A-[(2R,3R,4S,5S,6R)-3,4,5-Trihydroxy-6-(Hydroxymethyl)Oxan-2-Yl]Oxycarbonyl-1,2,3,4A,5,6,7,8,9,10,12,12A,14,14A-Tetradecahydropicen-3-Yl]Oxy]-3,5-Dihydroxy-4-[(2S,3R,4S,5R)-3,4,5-Trihydroxyoxan-2-Yl]Oxyoxane-2-Carboxylic Acid,Sodium Hydroxide,水反应生成地肤子皂苷 Ic
参考文献:Ma,W.-W.;Heinstein,P. F.;Mclaughlin,J. L.,J. Natur. Prod.,52,(1989) N,C. 1132-1135
标题:Ma,W.-W.;Heinstein,P. F.;Mclaughlin,J. L.,J. Natur. Prod.,52,(1989) N,C. 1132-1135