CAS: 33758-34-8; Heptyl Carbonochloridate

欧盟法规

[ECHA物质

上下游产品

phosgene n-heptan1ol bis(trichloromethyl) carbonatecarbonic acid heptyl ester-(2-nitro-phenyl ester) [4-(2-morpholino-ethoxy)-phenyl]-carbamic acid heptylester; hydr°Chloride Hexylamin°Carbonyloxyheptan Carbonic acid heptyl ester 4-[5-(4-nonyloxy-phenyl)-[1,3,4]thiadiazol-2-yl]-phenyl ester

正庚醇,三光气置于吡啶体系中,用 二氯甲烷 用作溶剂,化学反应 2.0H,以84.6%的收率获得氯甲酸正庚酯
参考文献:Shi,Haibo; Hu,Weixiao; Sun,Yaquan,Journal Of Chemical Research,2004,# 10,P. 708-709
标题:Shi,Haibo; Hu,Weixiao; Sun,Yaquan,Journal Of Chemical Research,2004,# 10,P. 708-709

专利信息

专利号:US-7064122-B2
优先权日:2001-12-20
标题:Pancreatic lipase inhibitor compounds, their synthesis and use
发明人：WITTER DAVID; CASTELHANO ARLINDO
权利人:OSI PHARM INC
摘要:The subject invention features compounds having the structure: n n nwherein X is O, S, CH 2 or NR 5 ; Y is O or S; R 1 is H, substituted or unsubstituted C 1 -C 15 alkyl, C 1 -C 8 alkylaryl, —C(O)OR 4 , —C(O)NR 4 R 5 , —CR 6 R 6′ OR 4 , —CR 6 R 6′ OC(O)R 4 , —CR 6 R 6′ OC(O)NHR 7 , —C(O)NR 10 R 11 , —C(O)NR 8 R 9 NR 8 R 9 , —N(R 5 )C(O)NHR 5 , or CH 2 R 4 ; R 2 is a substituted or unsubstituted, straight chain C 1 —C 30 alkyl or branched C 3 -C 30 alkyl, aryl, alkylaryl, arylalkyl, heteroarylalkyl or cycloalkyl; R 3 is H or substituted or unsubstituted C 1 -C 6 alkyl or C 3 -C 10 cycloalkyl; R 4 is H or a substituted or unsubstituted, straight chain or branched, C 6 -C 30 alkyl, aryl, —CH 2 -aryl, aryl —C 1 -C 15 alkyl, heteroaryl-C 1 -C 15 alkyl or C 3 -C 10 cycloalkyl; R 5 is H or a substituted or unsubstituted, straight chain or branched, C 6 -C 30 alkyl, aryl C 1 -C 30 alkyl, heteroarylalkyl or cycloalkyl; R 6 and R 6′ are each independently H, substituted or unsubstituted C 1 -C 6 alkyl, dialkyl or C 3 -C 10 cycloalkyl or together form a 3-7 membered ring system; R 7 is H or substituted or unsubstituted C 1 -C 12 alkyl or C 3 -C 10 cycloalkyl; R 8 and R 9 are each independently H, substituted or unsubstituted C 1 -C 6 alkyl, C 1 -C 6 alkoxy, C 1 -C 6 alkylaryl, or NR 8 R 9 together form a substituted piperazine or piperidine ring or a dihydro-1H-isoquinoline ring system, or a specific enantiomer thereof, or a specific tautomer, or a pharmaceutically acceptable salt thereof and a method for treating diabetes or obesity by administering a therapeutically effective amount of the compounds of the invention.

专利号:CN-119504882-A
优先权日:2023-08-24
标题 :Synthesis method of GalNAc derivative

专利号:MX-PA04005863-A
优先权日:2001-12-20
标 题 :INHIBITING COMPOUNDS OF PANCREATIC LIPASE, ITS SYNTHESIS AND USE.