CAS: 35308-00-0; 4-Methoxyacridin-9-Ol

上下游产品

9-chloro-4-methoxyacridine 2'-methoxydiphenylamine-2-carboxylic acid 3-(2,6-dimethoxyphenyl)anthranil N,N-Diethyl-2-(2-methoxy-phenylamino)-benzamide 4-hydroxyacridine N-(2-Diethylamino-ethyl)-4-methoxy-acridon-(9)-hydr°Chlorid Metoxy-4, O-(diethylamino ethyl) acridine Methoxy-4, O-benzyl acridine

2-氯苯甲酸置于硫酸,铜,Potassium Carbonate体系中,用 戊醇 作为反应溶剂,化学反应 4.0H,反应生成 4-甲氧基-10H-吖啶-9-酮
参考文献:吖啶基间苯二酚作为具有协调饱和度的稳健氢键二维网络的自互补构建块.在客体改变,客体去除和主体改性时保留晶体结构
标题:吖啶基间苯二酚作为具有协调饱和度的稳健氢键二维网络的自互补构建块.在客体改变,客体去除和主体改性时保留晶体结构
摘要:吖啶基间苯二酚主体 3(9-(3,5-二羟基-1-苯基)吖啶)形成加合物,如 3.(苯),3.(氯仿),3.0.5(甲苯)和 3.(苯甲酸异丁酯).在吖啶环上具有额外 Oh 基团的改性吖啶醇主体 4(9-(3,5-二羟基-1-苯基)-4-羟基吖啶)提供诸如 4.(苯),4.(氯仿),4.0 之类的加合物. 5(甲苯).0.5(水),4.(甲醇).(水)和4.(乙酸乙酯).在晶体中,主体 3 和 4 形成氢键 (Oh...Oh) 聚(间苯二酚)链,这些链通过链间 Oh...N 氢键连接在一起,形成配位饱和的 (Oh...Oh.. .N) 由双氢键和反平行堆叠,自互补环状二聚体 3(2) 或 4(2) 组成的 2D 网络作为刚性结构单元,否则柔性 Oh...Oh 氢键由此被引入类似环烷的结构.事实证明,该网络在上述加合物中保存得非常好.客体分子在许多情况下是无序的,它们被结合在留下的空腔中.小极性客体与主体
DOI:10.1021/ja026704L

专利信息

专利号:US-8735586-B2
优先权日:2007-06-26
标 题 :Regioselective copper catalyzed synthesis of benzimidazoles and azabenzimidazoles
发明人：ALONSO JORGE; LINDENSCHMIDT ANDREAS; NAZARÉ MARC; URMANN MATTHIAS; HALLAND NIS; RKYEK OMAR
权利人:ALONSO JORGE; LINDENSCHMIDT ANDREAS; NAZARÉ MARC; URMANN MATTHIAS; HALLAND NIS; RKYEK OMAR; SANOFI SA
摘要:The present invention relates to a process for the regioselective synthesis of compounds of the formula I, n nwherein R0; R1; R2; R3; R4; R5; A1; A2; A3; A4, Q and J have the meanings indicated in the claims. The present invention provides a direct copper catalyzed regioselective process to a wide variety of unsymmetrical, multifunctional N-substituted benzimidazoles or azabenzimidazoles of formula I starting from 2-halo-nitroarenes and N-substituted amides.

专利号:EP-2173747-B1
优先权日:2007-06-26
标 题:A regioselective metal catalyzed synthesis of annelated benzimidazoles and azabenzimidazoles
发明人：ALONSO JORGE; LINDENSCHMIDT ANDREAS; NAZARE MARC; R KYEN OMAR; URMANN MATHIAS; HALLAND NIS
权利人:SANOFI SA
摘要:The present invention relates to a process for the regioselective synthesis of compounds of the formula I, wherein R1; R2; R3; R4; J1; J2; J3; J4 and G have the meanings indicated in the claims. The present invention provides a direct metal, e.g. palladium or copper, catalyzed, regioselective process to a wide variety of unsymmetrical, multifunctional N-substituted benzimidazoles or azabenzimidazoles of formula I starting from 2-halo-nitroarenes and N-substituted amides.

专利号:US-2007031854-A1
优先权日:1999-02-01
标题:Novel 10,10'-substituted-9,9'-biacridilidine luminescent molecules their preparation and uses
发明人：KATSILOMETES GEORGE W
权利人:KATSILOMETES GEORGE W
摘要:Novel symmetric, uniformly symmetric and asymmetric 10,10′-substituted-9,9′-biacridines and the synthesis of such symmetric, uniformly symmetric and asymmetric 10,10′-substituted-9,9′-biacridine molecules and their derivatives is disclosed. These molecules are shown to produce light by luminescence in the presence of signals. These symmetric, uniformly symmetric or asymmetric 10,10′-substituted-9,9′-biacridines are used alone or attached to haptens or macromolecules and are utilized as labels in the preparation of iluminescent homogeneous and heterogeneous assays. They are also used in conjunction with other label molecules to produce multiple analyte assays.

专利号:US-2010261909-A1
优先权日:2007-06-26
标题 :Regioselective copper catalyzed synthesis of benzimidazoles and azabenzimidazoles

专利号:WO-2009000413-A1
优先权日:2007-06-26
标题:A regioselective copper catalyzed synthesis of benzimidazoles and azabenzimidazoles

专利号:CA-2693142-A1
优先权日:2007-06-26
标题:A regioselective metal catalyzed synthesis of annelated benzimidazoles and azabenzimidazoles