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5-hydroxy-2-(hydroxymethyl)-4H-pyran-4-one 1-hexadecylcarboxylic acid 合成工艺路线路线简述
- 501-30-4 = 79725-98-7
反应条件:1.1 Catalysts: Pyridine Solvents: Dimethylformamide; 15 °C; 4 H,15 - 25 °C; 1 H,Rt; 12 H,Rt
标题:Synthesis Of Kojic Dipalmitate
作者:Shen,Xin-An
参考文献:Huaxue Shiji 日期:2015 卷标:37(5) 页码:478-480]
57-10-3 = 79725-98-7
反应条件:1.1 Reagents: Thionyl Chloride; 5 H,60 - 65 °C; 65 °C -> 75 °C; 2 H,75 °C2.1 Catalysts: Pyridine Solvents: Dimethylformamide; 15 °C; 4 H,15 - 25 °C; 1 H,Rt; 12 H,Rt
标题:Synthesis Of Kojic Dipalmitate
作者:Shen,Xin-An
参考文献:Huaxue Shiji 日期:2015 卷标:37(5) 页码:478-480]
501-30-4 = 79725-98-7
反应条件:1.1 Solvents: Pyridine; 20 °C; 20 °C -> 30 °C; 2 H,30 °C
标题:Preparation Of Kojic Dipalmitate
作者:Zhaona,Si-Tu; Et Al
参考文献:Jingxi Yu Zhuanyong Huaxuepin 日期:2009 卷标:17(18) 页码:23-24]
501-30-4 + 57-10-3 = 79725-98-7
反应条件:1.1 Catalysts: Triacylglycerol Lipase Solvents: Acetone; 400 Min,50 °C
标题:Double-Lipase Catalyzed Synthesis Of Kojic Dipalmitate In Organic Solvents
作者:Wang,Zhiyuan; Et Al
参考文献:Chemical Research In Chinese Universities 日期:2017 卷标:33(6) 页码:903-907]
57-10-3 = 79725-98-7
反应条件:1.1 Reagents: Triphosgene Solvents: Chlorobenzene; Rt -> 5 °C1.2 Catalysts: Triethylamine,Imidazole Solvents: Chlorobenzene; 1 H,< 5 °C; 1 H,Rt2.1 Solvents: Pyridine; 20 °C; 20 °C -> 30 °C; 2 H,30 °C
标题:Preparation Of Kojic Dipalmitate
作者:Zhaona,Si-Tu; Et Al
参考文献:Jingxi Yu Zhuanyong Huaxuepin 日期:2009 卷标:17(18) 页码:23-24
曲酸,棕榈酸置于4-二甲氨基吡啶,N,N'-二环己基碳二亚胺体系中,用 二氯甲烷 作为反应溶剂,化学反应 7.0H,以93.5%的收率获得产物曲酸双棕榈酸酯
参考文献:코직산 유도체의 제조방법 및 이로부터 제조된 코직산 유도체를 포함하는 화장료 조성물
标题:코직산 유도체의 제조방법 및 이로부터 제조된 코직산 유도체를 포함하는 화장료 조성물
摘要:这项发明涉及制备草酸衍生物的方法和包含制备草酸衍生物的美白功能化妆品组合物.
海关参考信息
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2912110000-甲醛
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专利信息
专利号:US-4990330-A
优先权日:1987-09-25
标 题 :Compositions for topical use having melanin synthesis-inhibiting activity
发明人:OYAMA YASUAKI
权利人:SANSHO SEIYAKU KK
摘要:Compositions for topical use having melanin synthesis-inhibiting activity comprising kojic acid or its esters and at least one compound selected from the group consisting of azelaic acid, tropolone, lipoic acid, sorbic acid, glucosamine, derivative of glucosamine, tunicamycin, deoxynojirimycin, glutathione, cystein, hydroquinone, derivative of hydroquinone, dehydroacetic acid, chelidonic acid and lipoamide. The compositions have excellent human skin-whitening effect and anti-suntan effect.
专利号:US-2010093823-A1
优先权日:2008-04-30
标 题 :Steroidal compounds as melanogenesis modifiers and uses thereof
发明人:ORLOW SETH J; KOMATSU LI NI
权利人:ORLOW SETH J; KOMATSU LI NI
摘要:A method for the identification of compounds) that control melanin synthesis (melanogenesis), and the preparation and use of such compounds, and compositions and formulations thereof to modify (e.g., inhibit) melanin production are disclosed. A representative compound of the invention is defined by formula I: n n n n n n n n n n The compounds may be prepared as pharmaceutical and cosmetic compositions, and in one embodiment, may be prepared in combination with each other, and with other melanogenesis inhibiting formulations. The compounds, compositions and formulations of the invention may be used for the prevention and treatment of conditions that are causally related to aberrant melanogenesis activity including, by way of non-limiting example, hyperpigmentation and others.