CAS: 10160-24-4; 7-Bromo-1-Heptanol

相似化合物

10160-24-4 54049-24-0 29823-18-5

上下游产品

ethyl 7-bromoheptanoate 1,7-heptandiol methyl 7-bromoheptanoate 8-Bromo-1-°Ctene 7-bromo-1-(2-tetrahydropyranyloxy)heptane 7-(phenylseleno)heptan-1-ol 7-bromoheptanal 7-hydroxy-heptyl-triphenyl-phosphonium bromide

7-溴庚酸甲酯置于lithium Aluminium Tetrahydride体系中,用 四氢呋喃 用作溶剂,化学反应生成7-溴-1-庚醇
参考文献:(+/-)-Recifeiolide 和 (R)-(+)-蓖麻酸内酯的立体选择性总合成
标题:(+/-)-Recifeiolide 和 (R)-(+)-蓖麻酸内酯的立体选择性总合成
摘要:天然存在的大环内酯 (+/-)-Recifeiolide 是立体选择性合成的.(E)-11-羟基-8-十二碳烯酸(5)是由11-羟基-8-十二碳烯酸通过锂还原立体选择性地获得,酸(5)环化为(+/-)-Recifeiolide,收率极好通过其 6-苯基-2-吡啶酯.类似地,(R)-(+)-蓖麻油酸被内酯化以高产率提供相应的内酯.
Doi:10.1246/cl.1977.959

专利信息

专利号:US-5637757-A
优先权日:1995-04-11
标 题 :One-pot synthesis of ring-brominated benzoate compounds
发明人：HILL JOHN E; FAVSTRITSKY NICOLAI A; MAMUZIC RASTKO I; BHATTACHARYA BHABATOSH
权利人:GREAT LAKES CHEMICAL CORP
摘要:A method of preparing tetrabromobenzoate compounds from tetrabromophthalic anhydride by reacting tetrabromophthalic anhydride with alcohol in the presence of a decarboxylation catalyst. The reaction may be carried out in an excess of alcohol, or with a near stoichiometric amount of alcohol by performing the reaction in an inert solvent.

专利号:WO-2010115869-A1
优先权日:2009-04-03
标 题 :Propofol phosphonyl derivatives, synthesis, and use in long acting formulations
发明人：GONNISSEN YVES RENE JOHANNA PAUL
权利人:SEPS PHARMA N V; GONNISSEN YVES RENE JOHANNA PAUL
摘要:This invention relates to compounds represented by the structural formula (I), and the salts and stereoisomers thereof, wherein: - L is a linker selected from the group consisting of -(CH 2 ) P -O-, a single bond, formula (IA), -(CH 2 ) 1-8 -O-X(O)-, and - p is an integer from 1 to 8, - each R 3 and each R 4 is independently selected from the group consisting of C 1-20 alkyl, C 3-12 alkyl, C 3-12 cycloalkyl-C 1-4 alkyl, saturated heterocyclyl and saturated heterocyclyl-C 1-4 alkyl, and - X and Y are each independently C or S(O), - Z is selected from the group consisting of O, S(O) and NR 5 , - W is selected from the group consisting of halogen, OH, S(O)H and O - M + wherein M + is a monovalent cation; and - R 5 is selected from the group consisting of hydrogen and C 1-10 alkyl. These compounds are useful pharmaceutical agents with improved oral bioavailability.

专利号:WO-9632368-A1
优先权日:1995-04-11
标题:One-pot synthesis of ring-brominated benzoate compounds

专利号:WO-2024230844-A1
优先权日:2023-05-11
标 题:Cationic lipids and preparation method thereof
发明人：MASHIACH ROI
权利人:RIBOX THERAPEUTICS HK LTD
摘要:The present invention provides cationic lipids and lipid nanoparticle formulations comprising these lipids, alone or in combination with other lipids. These lipid nanoparticles may be formulated with nucleic acids to facilitate their intracellular delivery both in vitro and for therapeutic applications. The present invention also provides methods of chemical synthesis of these lipids.

专利号:EP-0825974-A1
优先权日:1995-04-11
标 题 :One-pot synthesis of ring-brominated benzoate compounds

专利号:CA-2217760-A1
优先权日:1995-04-11
标题:One-pot synthesis of ring-brominated benzoate compounds