CAS: 102-52-3; 1,1,3,3-Tetramethoxypropane

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CAS号926-65-8 异丙基乙烯基醚 | CAS号149-73-5 原甲酸三甲酯 | CAS号111-34-2 乙烯基正丁醚 | CAS号764-47-6 正丙基乙烯基醚 | CAS号107-25-5 乙烯基甲醚 | CAS号108-05-4 乙酸乙烯酯 | CAS号67-56-1 甲醇 | CAS号107-02-8 丙烯醛 | CAS号542-92-7 环戊二烯 | CAS号606-45-1 2-甲氧基苯甲酸甲酯 | CAS号3463-30-7 1-(4-硝基苯基)-1H-吡唑 | CAS号50351-72-9 2-(苄基氨基)烟腈 | CAS号35715-67-4 1-(4-甲氧基苯基)-1H-吡唑 | CAS号534-25-8 3H-1,2-二硫杂环戊二烯-3-硫酮 | CAS号52159-67-8 3-氯-2-羟基苯甲酸甲酯 | CAS号38353-09-2 2-羟基嘧啶盐酸盐 | CAS号858523-28-1 METHYL 2-METHOX... | CAS号93-89-0 苯甲酸乙酯 | CAS号5053-43-0 2-甲基嘧啶

5,8,11,14,17-Eicosapentaenoic Acid Methyl Ester 反应生成1,1,3,3-四甲氧基丙烷
参考文献:Mittelbach,Martin;Poklukar,Norbert,Chem. And Phys. Lipids,55,(1990) N,C. 67-72
标题:Mittelbach,Martin;Poklukar,Norbert,Chem. And Phys. Lipids,55,(1990) N,C. 67-72

专利信息

专利号:US-7897762-B2
优先权日:2006-09-14
标 题:Kinase inhibitors useful for the treatment of proliferative diseases
发明人：FLYNN DANIEL L; PETILLO PETER A; KAUFMAN MICHAEL D; PATT WILLIAM C
权利人:DECIPHERA PHARMACEUTICALS LLC
摘要:The present invention relates to novel kinase inhibitors and modulator compounds useful for the treatment of various diseases. More particularly, the invention is concerned with such compounds, kinase/compound adducts, methods of treating diseases, and methods of synthesis of the compounds. Preferably, the compounds are useful for the modulation of kinase activity of Raf kinases and disease polymorphs thereof. Compounds of the present invention find utility in the treatment of mammalian cancers and especially human cancers including but not limited to malignant melanoma, colorectal cancer, ovarian cancer, papillary thyroid carcinoma, non small cell lung cancer, and mesothelioma. Compounds of the present invention also find utility in the treatment of rheumatoid arthritis and retinopathies including diabetic retinal neuropathy and macular degeneration.

专利号:US-8188113-B2
优先权日:2006-09-14
标 题 :Dihydropyridopyrimidinyl, dihydronaphthyidinyl and related compounds useful as kinase inhibitors for the treatment of proliferative diseases
发明人：FLYNN DANIEL L; PETILLO PETER A; KAUFMAN MICHAEL D; PATT WILLIAM C
权利人:FLYNN DANIEL L; PETILLO PETER A; KAUFMAN MICHAEL D; PATT WILLIAM C; DECIPHERA PHARMACEUTICALS INC
摘要:The present invention relates to novel dihydropyridopyrimidinyl, dihydronaphthyridinyl, and related compounds which are kinase inhibitors and modulator useful for the treatment of various diseases. More particularly, the invention is concerned with such compounds, kinase/compound adducts, methods of treating diseases, and methods of synthesis of the compounds. Preferably, the compounds are useful for the modulation of kinase activity of Raf kinases and disease polymorphs thereof. Compounds of the present invention find utility in the treatment of mammalian cancers and especially human cancers including but not limited to malignant melanoma, colorectal cancer, ovarian cancer, papillary thyroid carcinoma, non small cell lung cancer, and mesothelioma. Compounds of the present invention also find utility in the treatment of rheumatoid arthritis and retinopathies including diabetic retinal neuropathy and macular degeneration.

专利号:US-2005085492-A1
优先权日:2003-10-20
标 题:Stereoselective process for the synthesis of chiral garft compounds and intermediates
发明人：RAHMAN LEERA
权利人:AGOURON PHARMACEUTICALS MINC
摘要:The present invention describes a stereoselective preparation of derivatives and precursors of molecules having formula 1: n nMethod of preparing the compounds, intermediates and derivatives are described. The methods described herein allow the preparation of diastereomeric forms of compound having formula 1. The compounds of the invention are GARFT inhibitors.

专利号:US-6372785-B1
优先权日:2000-05-04
标 题:Synthesis of 1,8-dichloro-anthracene analogues and pharmaceutical compositions based thereon
发明人：HUANG HSU-SHAN
权利人:KEITH CHAN PRESIDENT GLOBOASIA
摘要:The invention provides novel anthracene compounds useful in the treatment of allergic, inflammatory, and tumor conditions and therapeutic compositions containing such compounds or their pharmaceutically acceptable salts. The compounds of the invention are novel 1,8-dichloro-anthracene derivatives or analogs thereof. According to the practice of the invention, there are provided 9-substituted 1,8-dichloro-anthracene compounds of the Formula III:wherein R represents a straight or branched chain alkyl group having 1-6 carbons and may be substituted with one or more of the groups R1, wherein R1 represents the groups selected from COOH or an ester alky thereof having 1 to 4 carbons, -OH, halogen, NO2, CH3O, CH3CH2O, phenyl and CH3CH2CH2O. Alternatively, R may be phenyl, benzyl, or phenyl or benzyl substituted with one or more groups R2, wherein R2 represents the a group select from a straight or branched chain alkyl group having 1 to 4 carbon atoms, halogen, NO2, CH3O, CH3CH2O, CH3CH2CH2O and an ester alkyl having an alkyl group of 1 to 4 carbon atoms.

专利号:US-8362034-B2
优先权日:2005-11-17
标 题:Quinoline compound, and composition containing centipede extract or compounds isolated therefrom for prevention and treatment of cardiovascular disease
发明人：PARK HO YONG; JEONG TAE-SOOK; OH HYUN-WOO; LEE WOO-SONG; PARK DOO-SANG; HAN JONG-MIN
权利人:KOREA RES INST OF BIOSCIENCE; PARK HO YONG; JEONG TAE-SOOK; OH HYUN-WOO; LEE WOO-SONG; PARK DOO-SANG; HAN JONG-MIN
摘要:The present invention relates to a composition for the prevention and treatment of cardiovascular diseases containing the novel quinoline compound, the centipede extracts or compounds isolated from the extracts. The novel quinoline compound, the centipede extracts or a quinoline compound and a phenol compound isolated from the extracts of the invention exhibit excellent LDL-antioxidant activity, ACAT inhibiting activity, and anti-inflammatory activities, so that they can be included as an effective ingredient in a composition for the prevention and treatment of cardiovascular disease including hyperlipidemia, atherosclerosis, coronary heart disease, and myocardial infarction mediated by LDL-oxidation, cholesteryl ester synthesis and accumulation, and inflammation.

专利号:US-3950160-A
优先权日:1972-09-27
标题:Inhibiting the growth of weeds with 2-substituted pyrdidopyimidines and salts thereof
发明人：ABU EL-HAJ MARWAN J; DOMINY BERYL WILLIAM
权利人:PFIZER
摘要:2-Substituted pyridopyrimidines and their alkali and alkylamine salts as herbicides, and processes for the synthesis of starting materials leading to the preparation thereof.