CAS: 108-19-0; Biuret

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Sodium Dicyanamide置于h2O体系中,用 盐酸 用作溶剂,化学反应生成缩二脲
参考文献:Madelung,W.; Kern,E.,Justus Liebigs Annalen Der Chemie,1922,Vol. 427,P. 1-26
标题:Madelung,W.; Kern,E.,Justus Liebigs Annalen Der Chemie,1922,Vol. 427,P. 1-26

专利信息

专利号:US-2012130699-A1
优先权日:2010-11-22
标 题 :Method of molecular design and synthesis of therapeutic and preventive drugs
发明人：MARTYNOV ARTUR; FARBER BORIS S; FARBER SONYA SOPHYA
权利人:MARTYNOV ARTUR; FARBER BORIS S; FARBER SONYA SOPHYA
摘要:Industrial Application: This invention may be used in human and veterinary medicine for the design (creation and synthesis) of therapeutic and preventive drugs that are effective for the treatment of oncological and viral human and animal illnesses and for the design of new medicines. n Summary of the Invention: A new method of design and synthesis of therapeutic and preventive drugs in which a biopolymer target (protein, DNA, RNA, or a mixture of these) is used, and in the capacity of a ligand, the same biopolymer target is used, which is cut into oligomer fragments (nucleases, synthetic nucleases, and proteases); the fragments are modified through changing their charges to the opposite charge (acylation of anhydrides of dicarbonate acids or alkylation with halogen-carbonic acids). Also in the capacity of a ligand, the same biopolymer target is used, which is modified by partially changing the molecules' charges to the opposite with the creation of supramolecular biopolymer assemblies. We used supramolecule assemblies made from oligomers that were products of the hydrolysis of biopolymers, but with a change of the charge of the molecules to the opposite charge, as well as the partial change of the charges of the target biopolymers. n Technical Result: A method of molecular design and synthesis of new, unique therapeutic and preventive drugs based on self-organizing systems. The application of the method will allow a significant cut to expenditures on the design and synthesis of new drugs, expand the activity spectra of existing protein gene-engineered drugs, and create new classes of dynamic therapeutic and preventive drugs that self-adapt to the organism and target.

专利号:US-8927770-B2
优先权日:2011-05-10
标题 :High-yield process for the synthesis of urea
发明人：CARLESSI LINO; GIANAZZA ALESSANDRO
权利人:CARLESSI LINO; GIANAZZA ALESSANDRO; SAIPEM SPA
摘要:A process for the direct synthesis of urea from ammonia and carbon dioxide at high pressures and temperatures, with the formation of ammonium carbamate as intermediate, comprising a decomposition step of the ammonium carbamate and stripping of the gases formed, operating substantially at the same pressure as the synthesis step, wherein the recycled liquid streams are fed, at least partially, to the same decomposition and stripping step after being preheated by heat exchange with a stream included in the high-pressure synthesis cycle.

专利号:US-2022219156-A1
优先权日:2019-04-29
标题:Catalyst for the catalytic synthesis of urea
发明人：GLOTZBACH CHRISTOPH; TENHUMBERG NILS; EL HAWARY TAREK; MAKHYNYA YEVGENY; LEITNER WALTER; KLANKERMAYER JÃœRGEN; SCHUMACHER HANNAH
权利人:THYSSENKRUPP IND SOLUTIONS AG; THYSSENKRUPP AG
摘要:A ruthenium-phosphine complex can be used as a catalyst in a method for the catalytic synthesis of urea. The method may comprise more particularly a reaction of formamide or of formamide with ammonia in the presence of the catalyst to form urea and hydrogen. Through the use of the ruthenium-phosphine complex as the catalyst, catalytic preparation of urea from formamide or from formamide with ammonia is provided for the first time. This allows for synthesis under mild conditions and virtually no formation of byproducts. Further, using an acid as a cocatalyst in the catalytic synthesis or the reaction can lead to an improvement in urea yield.

专利号:US-11535586-B2
优先权日:2018-11-22
标题 :Process for the synthesis of urea
发明人：MARRONE LEONARDO
权利人:CASALE SA
摘要:A process for synthesis of urea from CO 2 and NH 3 wherein a steam flow ( 13 ) produced in the condenser ( 3 ) of a high-pressure synthesis loop is compressed to raise its pressure and temperature before using the steam as a heat source for a downstream step of the process.

专利号:US-2024424490-A1
优先权日:2021-01-25
标 题 :Method of synthesis of carbon-supported platinum group metal or metal alloy nanoparticles
发明人：WNUK PAWEL; LEWERA ADAM; JURCZAKOWSKI RAFAL; POWALA FILIP; KOLODZIEJCZYK JAN
权利人:UNIV WARSZAWSKI
摘要:The presented invention relates to a method of synthesis of carbon-supported platinum group metal or metal alloy nanoparticles, which comprises the following steps:n adsorbing on carbon support complexes of a platinum group metal with a urea complexing agent selected from a group comprising urea, urea derivative, a mixture of urea with at least one urea derivative, and a mixture of at least two urea derivatives; and reducing the complexes adsorbed on the carbon support to metal nanoparticles, forming a product of carbon-supported metal nanoparticles. nn The invention also provides the use of the carbon-supported platinum group metal or metal alloy nanoparticles obtained by the method of the invention as catalyst. n The present invention further relates to a method of adsorption of precursors of platinum group metals on the surface of a carbon support and use of complexes of platinum group metals with urea complexing agent for adsorption of platinum group metal precursors on carbon support.

专利号:US-2023183177-A1
优先权日:2020-04-24
标题:Enantioselective chemo-enzymatic synthesis of optically active amino amide compounds
发明人：GRILL BIRGIT; WINKLER MARGIT; SCHWAB HELMUT; STROHMEIER GERNOT; DONSBACH KAI; WALDVOGEL SIEGFRIED R; ARNDT SEBASTIAN; WEIS DOMINIK
权利人:PHARMAZELL GMBH
摘要:The present invention relates to a novel biocatalytic process for the stereoselective preparation of alpha amino amide compounds catalyzed by NHase enzymes. A further aspect of the invention relates to novel NHase enzymes as well as further improved NHase enzyme mutants, nucleic acid molecules encoding these enzymes, recombinant microorganisms suitable for preparing such enzymes and mutants. Another aspect of the invention relates to a chemo-biocatalytic process for the preparation of lactam compounds comprising the new catalytic process for the preparation of alpha amino amide compounds catalyzed by NHase enzymes, as well as the chemical oxidation of the alpha amino amide by applying certain chemical oxidation catalysts suitable for converting the alpha amino amide under retention of its stereochemical configuration to the respective lactam. The novel chemo-biocatalytic process is particularly suited for the synthesis of valuable pharmaceutical compounds, like in particular (S)-Levetiracetam.