CAS: 156-83-2; 6-Chloropyrimidine-2,4-Diamine

上下游产品

2,4,6-trichloropyrimidine 4-amino-2,6-dichloropyrimidine 2-Amino-4,6-dichloropyrimidine 2,6-diamino-3H-pyrimidin-4-one 2,4-Diamino-6-piperidinopyrimidine 2,4-diamino-6-methoxypyrimidine 6-ethoxypyrimidine-2,4-diamine N4-(4-arsenoso-phenyl)-pyrimidine-2,4,6-triyltriamineN4-(4-arsenoso-phenyl)-pyrimidine-2,4,6-triyltriamine

4-氨基-2,6-二氯嘧啶置于乙醇,氨体系中,化学反应生成2,4-二氨基-6-氯嘧啶
参考文献:Buettner,Chemische Berichte,1903,Vol. 36,P. 2234
标题:Buettner,Chemische Berichte,1903,Vol. 36,P. 2234

专利信息

专利号:US-6818633-B2
优先权日:2001-06-29
标题:Antiviral compounds and methods for synthesis and therapy
发明人：BALZARINI JAN M R; DE CLERCQ ERIK D A; HOLY ANTONIN
权利人:ACAD OF SCIENCE CZECH REPUBLIC; REGA STICHTING
摘要:Novel compounds are provided having formula (I)whereR1, R2, R3, R4, Z, X and * are defined herein. Also provided are antiviral methods for use and processes for synthesis of the compounds of formula (I).

专利号:US-5401844-A
优先权日:1983-04-11
标 题 :Regulation of enzymes which utilize tetrahydrobiopterin or tetrahydrofolate cofactors with 6,6-disubstituted-tetrahydropteridines
发明人：AYLING JUNE E; BAILEY STEVEN W
权利人:UNIV SOUTH ALABAMA
摘要:6-[2'-Amino-2',2'-disubstituted-ethylamino]-pyrimidines of the structure: ##STR1## in which X=H, NH 2 or NO 2 , which are novel intermediates in the synthesis of quinoid 6,6-disubstituted-dihydro- and 6,6-disubstituted-tetrahydro-pteridines, are claimed.

专利号:US-8895747-B2
优先权日:2009-07-27
标 题 :Method and substances for preparation of N-substituted pyridinium compounds
发明人：HEINDL DIETER; MAERZ HERIBERT; SCHMIDT AXEL
权利人:HEINDL DIETER; MAERZ HERIBERT; SCHMIDT AXEL; ROCHE DIAGNOSTICS OPERATIONS
摘要:Methods for the synthesis of N-substituted pyridinium compounds by using an N-heteroaryl substituted pyridinium salt (Zincke salt) and reacting it with a nucleophilic amine are provided. Novel purine-substituted pyridyl compounds, which may be useful reagents in the above reaction, are also disclosed.

专利号:US-5874433-A
优先权日:1993-11-29
标题 :Blocking utilization of tetrahydrobiopterin to block induction of nitric oxide synthesis
发明人：GROSS STEVEN S
权利人:CORNELL RES FOUNDATION INC
摘要:Inhibitor of the use of tetrahydrobiopterin as a cofactor for nitric oxide synthase, e.g., substituted 4-phenyl(hydropyridines) such as 1-methyl-4-(3',4'-dihydroxyphenyl)-1,2,3,6-tetrahydropyridine or, 4-(3',4'-dihydroxyphenyl)-1,2,3,6-tetrahydropyridine) or tetrahydropterin analog which does not replace tetrahydrobiopterin as a substrate for nitric oxide synthase such as (6R,S)-6,7-dimethyl-tetrahydropterin or (6R,S)-tetrahydrofolic acid or 2,4-diamino-, 2,6-diamino, or 4,6-diamino mono- or disubstituted pyrimidines or the corresponding pyrimidine-3-oxides such as 2,4-diamino-6-(diethylamino)pyrimidine, 2,4-diamino-6-piperidino-pyrimidine-3-oxide, 2,4-diamino-6-hydroxypyrimidine, 4,6-diamino-2-hydroxypyrimidine or 2,5-diamino-4,6-dihydroxypyrimidine is administered to inhibit nitric oxide synthesis from arginine in vascular cells in a subject in need of such inhibition (e.g., for prophylaxis or treatment of cytokine- or endotoxin-induced hypotension (e.g., septic shock). The latter two types are advantageously administered with nitric oxide synthase inhibitors (concurrent therapy) or to potentiate the effect of α 1 -adrenergic agonists in the prophylaxis or treatment of induced hypotension.

专利号:US-7750090-B2
优先权日:2003-01-30
标 题:Moleculary imprinted polymers for extraction of components from foodstruffs
发明人：SELLERGREN BOERJE; MANESIOTIS PANAGIOTIS; HALL ANDREW J
权利人:MIP TECHNOLOGIES AB
摘要:The present invention relates to a novel class of water compatible molecularly imprinted polymers (AquaMIPs) capable of selectively binding target molecules such as riboflavin, or analogues thereof, in water or aqueous media, their synthesis and use thereof in food processing and extraction or separation processes.

专利号:US-6844343-B1
优先权日:1999-09-17
标 题 :N-substituted 4-aminopteridines, synthesis and use thereof as pharmaceutical agent
发明人：PFLEIDERER WOLFGANG; SCHMIDT HARALD; FROEHLICH LOTHAR; KOTSONIS PETER; TAGHAVI-MOGHADAM SHAHRIYAR
权利人:VASOPHARM BIOTECH GMBH
摘要:Compounds of formula (I), where preferably: A=a bridge of partial formula (II) or (III), R<1 >and R<2>=independently (substituted) alkyl, aryl or aralkyl, or together form a heterocycle, R<3>=H, -CO-Alkyl, or -CO-Aryl, R<4>=Aryl, -CO-O-Aryl or -CO-Aryl and R<5>=H, are potent inhibitors of NO-synthase and are suitable as pharmaceutical agents of prophylaxis and treatment of disease states associates with a disturbed NO metabolism.