专利号:WO-2024209478-A1 优先权日:2023-04-07 标题:Synthesis of cyclic ketone from cyclic amino acid 发明人:BICIDI JAYAPAL REDDY; RAMIYA RAJARAM AMARESH; PILLAI BIJUKUMAR GOPINATHAN 权利人:ADAMA MAKHTESHIM LTD 摘要:A process for preparation of a compound of formula (I) in which R is hydrogen, hydroxyl, C1-C10 -alkyl, C1-C10 -alkoxy, C1-C4 -alkylamino, di- C1-C4 - alkylamino, C1-C4 -acylamino, COOR1, — CH2— R2 where R1 is hydrogen or C1-C4 -alkyl or R2—CH2— and R2 is hydroxyl, C1-C4 -alkoxy, C1-C4 -alkylamino or di- C1-C4 -alkylamino; n represents the number of carbon atoms and is any integer of 0, 1, 2; and m represents the number of R groups and satisfies the relation: 0≤m≤8+2n. The process comprising: (a) oxidation of a compound of formula (III) wherein R is as defined above, with salt of a hypohalous acid to give compound of the formula (II), wherein R, n and m are as defined above, and X is Cl, Br or I; and (b) hydrolysis in the presence of water of the compound of the formula (II).
专利号:WO-2025056767-A1 优先权日:2023-09-15 标题 :Process for the preparation of enantiomerically enriched aliphatic amines 发明人:BOU HAMDAN FARHAN; GODINEAU EDOUARD; SMEJKAL TOMAS; DUMEUNIER RAPHAEL; BOUSSEMGHOUNE MOHAMED ABDELOUAHAB; BLUM MATHIAS 权利人:SYNGENTA CROP PROTECTION AG 摘要:The present invention relates to a process for the preparation of enantiomerically enriched cyclobutylamines of formula (I) from α-tertiary cyclobutanones and reacting said enantiomerically enriched cyclobutylamines to enantiomerically enriched cyclobutylamides. Such compounds are useful intermediates in the synthesis of microbiocidal thiazole compounds.
专利号:US-2016073631-A1 优先权日:2013-03-04 标 题 :Process for the preparation of dihydropyrrole derivatives 发明人:EL QACEMI MYRIEM; SMITS HELMARS; CASSAYRE JEROME YVES; MULHOLLAND NICHOLAS PHILLIP; RENOLD PETER; GODINEAU EDOUARD; PITTERNA THOMAS 权利人:SYNGENTA PARTICIPATIONS AG; SYNGENTA LTD 摘要:The present invention provides stereoselective processes for the preparation of compounds of formula (I) n n n n n n n n n n n n wherein n P is phenyl, naphthyl, a 6-membered heteroaryl group containing one or two nitrogen atoms as ring members, or a 10-membered bicyclic heteroaryl group containing one or two nitrogen atoms as ring members, and wherein the phenyl, naphthyl and heteroaryl groups are optionally substituted; n R 1 is chlorodifluoromethyl or trifluoromethyl; n R 2 is optionally substituted aryl or optionally substituted heteroaryl; n n is 0 or 1; n including the process comprising n (a-i) reacting a compound of formula II n n n n n n n n n n n n n n n n wherein P, R 1 and R 2 are as defined for the compound of formula I; n with nitromethane in the presence a chiral catalyst to give a compound of formula III n n n n n n n n n n n n n n n n wherein P, R 1 and R 2 are as defined for the compound of formula I; and n (a-ii) reductively cyclising the compound of formula III to give the compound of formula I. n n n n n The invention also provides intermediates useful for processes for the synthesis of compounds of formula (I).
专利号:US-9233920-B2 优先权日:2010-06-11 标题 :Process for the preparation of dihydropyrrole derivatives 发明人:EL QACEMI MYRIEM; SMITS HELMARS; CASSAYRE JEROME YVES; MULHOLLAND NICHOLAS PHILLIP; RENOLD PETER; GODINEAU EDOUARD; PITTERNA THOMAS 权利人:EL QACEMI MYRIEM; SMITS HELMARS; CASSAYRE JEROME YVES; MULHOLLAND NICHOLAS PHILLIP; RENOLD PETER; GODINEAU EDOUARD; PITTERNA THOMAS; SYNGENTA PARTICIPATIONS AG; SYNGENTA LTD 摘要:The present invention provides stereoselective processes for the preparation of compounds of formula (I) wherein P is phenyl, naphthyl, a 6-membered heteroaryl group containing one or two nitrogen atoms as ring members, or a 10-membered bicyclic heteroaryl group containing one or two nitrogen atoms as ring members, and wherein the phenyl, naphthyl and heteroaryl groups are optionally substituted; R 1 is chlorodifluoromethyl or trifluoromethyl; R 2 is optionally substituted aryl or optionally substituted heteroaryl; n is 0 or 1; including the process comprising (a-i) reacting a compound of formula II wherein P, R 1 and R 2 are as defined for the compound of formula I; with nitromethane in the presence a chiral catalyst to give a compound of formula III Wherein P, R 1 and R 2 are as defined for the compound of formula I; and (a-ii) reductively cyclizing the compound of formula III to give the compound of formula I. The invention also provides intermediates useful for processes for the synthesis of compounds of formula (I).
专利号:WO-2023089578-A1 优先权日:2021-11-22 标题:A synthesis process of iron-bearing compositions and possible additional essential elements 发明人:MORMILE SILVIA; GUSMEROLI MARILENA; ZANARDI GIAMPAOLO; BIANCHI DANIELE; COTROMINO MICHELE; SARGIOTTO CHIARA; LIGUORI RICCARDO 权利人:GOWAN CROP PROT LIMITED 摘要:A synthesis process of iron-bearing compositions and possible additional essential elements is described for treating nutritional deficiencies in plants, in particular for the prevention and treatment of physiological alterations or nutritional unbalances in plants due to the deficiency of iron and other essential elements, and the iron-bearing compositions and possibly further essential elements obtained with said process.
专利号:US-2011230343-A1 优先权日:2008-10-24 标题 :Method for the Manufacture of Microparticles Comprising an Effect Substance 发明人:SCHROERS MICHAEL; DYLLICK-BRENZINGER RAINER; MERK MICHAEL; BARG HEIKO 权利人:BASF SE 摘要:A subject matter of the present invention is a process for the preparation of effect compound-comprising microparticles M comprising A) the formation of a crude suspension of microparticles A by means of enzymatic polyester synthesis in an inverse miniemulsion comprising enzyme, effect compound and polyester monomers; and B) the polymerization of wall monomers from the group consisting of ethylenically unsaturated monomers, polyisocyanates and polyepoxides in the crude suspension of microparticles A. Furthermore, the present invention relates to microparticles M which can be obtained by means of the process according to the invention and also to an agrochemical formulation comprising microparticles M. In addition, the present invention relates to the use of microparticles M prepared according to the invention as component in colorants, cosmetics, drugs, biocides, plant protection agents, fertilizers, additives for food or animal fodder, or auxiliaries for polymers, paper, textiles, leather, detergents or cleaners. Finally, the invention also relates to a method for combating undesirable plant growth, to a method for combating undesirable insect or acarid infestation on plants and/or for combating phytopathogenic fungi, and to seeds treated with the agrochemical formulation.
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合成参考文献
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