CAS: 609-70-1; 4-Hydroxynicotinic Acid

上下游产品

4-methoxypyridine-3-carbonitrile 3-(trinitromethyl)-pyridin-4-ol 4-Ethoxypyridin-3-carbonitril pyridin-4-ol methyl 4-hydroxypyridine-3-carboxylate 4-Hydroxy-nicotinsaeure-ethylester 4-chloronicotinic acid 4-hydroxy-5-nitronicotinic acid

4-氯吡啶置于水,Lithium Diisopropyl Amide体系中,用 四氢呋喃,正己烷 作为反应溶剂,化学反应生成 4-羟基烟酸
参考文献:Chemical Molecules That Inhibit The Slicing Mechanism For Treating Diseases Resulting From Splicing Anomalies
标题:Chemical Molecules That Inhibit The Slicing Mechanism For Treating Diseases Resulting From Splicing Anomalies
摘要:本发明涉及公式i至xxi中的化合物之一;包含至少一种这种化合物的药物组合物;以及使用至少一种这种化合物来制备一种药物,用于治疗主体中由至少一个剪接异常导致的遗传疾病.

专利信息

专利号:US-2004110228-A1
优先权日:2002-04-01
标 题:Combinatorial organic synthesis of unique biologically active compounds
发明人：MCALPINE SHELLI R; TAYLOR RACHEL E; BOLLA MEGAN L; SEGALL ANCA M
摘要:The invention provides a method for making a combinatorial library of cyclic compounds, such as Holliday junction-trapping compounds, comprising the steps of (a) obtaining a plurality of trimers according to the generic structure X 1- X 2- X 3 , wherein X 1 , X 2 and X 3 can be independently any naturally or nonnaturally occurring amino acids or peptidomimetics thereof; (b) optionally coupling a spacer S to the trimer at either end; (c) cyclizing two trimers or trimer-spacer conjugates in a head-to-tail orientation; thereby obtaining a combinatorial library of compounds, wherein the library does not include an unmodifed or naturally occurring Holliday Junction-trapping compounds. The invention additionally provides methods macrocyclic compounds that are synergimycin derivatives.

专利号:EP-1401829-B1
优先权日:2001-06-15
标题 :Novel heterocyclic antibacterial compounds
发明人：ZHI CHENGXIN; WRIGHT GEORGE E
权利人:MICROBIOTIX INC
摘要:The invention provides heterocyclic organic compounds that inhibit bacterial DNA polymerase IIIC and type II bacterial topoisomerase. The invention further provides compounds that are useful as intermediates in the synthesis of such heterocyclic organic compounds. Syntheses and uses of such heterocyclic organic molecules are also described.

专利号:EP-0376870-A1
优先权日:1988-12-30
标 题:A new organosilylpolyphosphoric reagent, its preparation and application to the process of synthesis of 3-carboxyquinolones or azaquinolones and their salts

专利号:US-6777420-B2
优先权日:2001-06-15
标题 :Heterocyclic antibacterial compounds
发明人：ZHI CHENGXIN; WRIGHT GEORGE E
权利人:MICROBIOTIX INC
摘要:The invention provides heterocyclic organic compounds that inhibit bacterial DNA polymerase IIIC and type II bacterial topoisomerase. The invention further provides compounds that are useful as intermediates in the synthesis of such heterocyclic organic compounds. Syntheses and uses of such heterocyclic organic molecules are also described.

专利号:US-5098462-A
优先权日:1985-08-20
标 题 :Substituted semi-carbazones and related compounds
发明人：ANDERSON RICHARD J; LEIPPE MICHAEL M; BAMBERG JOE T
权利人:SANDOZ LTD
摘要:Substituted semicarbazones, thiosemicarbazones and isothiosemicarbazones and salts thereof, intermediates therefor, synthesis thereof, and the use of said compounds for the control of weeds.

专利号:US-5098466-A
优先权日:1985-08-20
标 题 :Compounds
发明人：ANDERSON RICHARD J; LEIPPE MICHAEL M; BAMBERG JOE T
权利人:SANDOZ LTD
摘要:Substituted semicarbazones, thiosemicarbazones and isothiosemicarbazones and salts thereof, intermediates therefor, synthesis thereof, and the use of said compounds for the control of weeds.