CAS: 144-83-2; 4-Amino-N-(Pyridin-2-yl)Benzenesulfonamide

上下游产品

CAS号19077-98-6 N-[4-(2-Pyridin... | CAS号504-29-0 2-氨基吡啶 | CAS号121-60-8 对乙酰氨基苯磺酰氯 | CAS号1028-11-1 4-NITRO-N-2-PYR... | CAS号1213-38-3 4-氯-N-(吡啶-2-基)苯磺酰胺 | CAS号98-74-8 4-硝基苯磺酰氯 | CAS号98-62-4 4-氨基苯磺酰氟 | CAS号109-04-6 2-溴吡啶 | CAS号63-74-1 磺胺 | CAS号5029-67-4 2-碘吡啶 | CAS号39588-26-6 咪唑并[1,2-a]吡啶-2-胺 | CAS号19077-98-6 N-[4-(2-Pyridin... | CAS号504-29-0 2-氨基吡啶 | CAS号722-27-0 4,4'-二硫代二苯胺 | CAS号6325-93-5 4-硝基苯磺酰胺 | CAS号63-74-1 磺胺 | CAS号121-57-3 对氨基苯磺酸 | CAS号29821-91-8 Benzenesulfonam... | CAS号29817-71-8 Benzenesulfonam...

N-硝基-N-吡啶-2-基苯磺酰胺置于铁粉,氯化铵体系中,用 甲醇 用作溶剂,化学反应 3.0H,以81%的收率获得磺胺吡啶
参考文献:一种对氨基苯磺酰胺化合物的制备方法
标题:一种对氨基苯磺酰胺化合物的制备方法
摘要:本发明属于有机合成技术领域和磺胺类药物领域,具体公开了一种对氨基苯磺酰胺化合物的制备方法.所述制备方法具体包括以下步骤:将对硝基苯二硫醚和杂芳胺化合物在催化剂,氧化剂和溶剂条件下反应,制得对硝基苯磺酰胺;将对硝基苯磺酰胺在还原剂和溶剂条件下反应,得到对氨基苯磺酰胺化合物.本发明采用廉价的锆盐和铜盐作为催化剂,直接用稳定低毒的二硫醚作为磺酰化试剂,直接对胺进行磺酰化,常压下即可完成,避免制备磺酰氯这一步骤,也就避免了氯气和二氯亚砜等强腐蚀性物种的使用,方法更加简单,环保,符合当前世界发展绿色化工的要求.

专利信息

专利号:US-10768157-B2
优先权日:2015-10-20
标 题:Materials and methods for the detection of trace amounts of substances in biological and environmental samples
发明人：KABIR ABUZAR; FURTON KENNETH G
权利人:KABIR ABUZAR; FURTON KENNETH G; THE FLORIDA INTERNATIONAL UNIV BOARD OF TRUSTEES
摘要:The subject invention provides chemical compositions and synthesis strategies to create molecularly imprinted polymers (MIPs) via sol-gel processes. In a specific embodiment, the subject invention utilizes a(n) organic, inorganic, or metallic template analyte to create a hybrid organic-inorganic or inorganic three-dimensional network possessing cavities complementary to the shape, size, and functional orientation of the template molecule or ions. The subject invention further pertains to the use of the novel MIPs as selective solid phase extraction (SPE) sorbents for pre-concentration and clean-up of trace substances in biological and environmental samples. Synthesis of other molecularly imprinted polymers with environmental, pharmaceutical, chemical, clinical, toxicological, and national security implications can be conducted in accordance with the teachings of the subject invention.

专利号:US-8557979-B2
优先权日:2004-06-10
标题 :Carbapenem antibacterials with gram-negative activity and processes for their preparation
发明人：CHOI WOO-BAEG; KOWALIK EWA
权利人:CHOI WOO-BAEG; KOWALIK EWA; FOB SYNTHESIS INC
摘要:The present invention provides β-methyl carbapenem compounds and pharmaceutical compositions useful in the treatment of bacterial infections and methods for treating such infections using such compounds and/or compositions. The invention includes administering an effective amount of a carbapenem compound or salt and/or prodrug thereof to a host in need of such a treatment. The present invention is also in the field of synthetic organic chemistry and is specifically provides an improved method of synthesis of β-methyl carbapenems which are useful as antibacterial agents.

专利号:US-10933051-B2
优先权日:2017-06-09
标 题 :Carbapenem compounds and compositions for the treatment of bacterial infections
发明人：CHOI WOO-BAEG; TOMIOKA TAKASHI; JOO HYUNG-YEUL; TRUONG PHONG; MIN BRIAN
权利人:FOB SYNTHESIS INC
摘要:The present invention provides carbapenem compounds and pharmaceutical compositions useful in the treatment of bacterial infections, including drug resistant or multiple-drug resistant bacterial infections, and methods for treating such infections using such compounds and/or compositions. The invention includes administering an effective amount of a carbapenem compound or salt and/or prodrug thereof to a host in need of such a treatment.

专利号:US-8754197-B2
优先权日:2004-07-07
标题:Synthesis of azo bonded immunoregulatory compounds
发明人：RIGGS-SAUTHIER JENNIFER A; EKWURIBE NNOCHIRI N
权利人:RIGGS-SAUTHIER JENNIFER A; EKWURIBE NNOCHIRI N; BIOCON LTD
摘要:Methods are disclosed for preparing compounds of Formula I: n nwhere R 1 , R 3 , and R 4 are independently hydrogen or C 1 to C 4 alkyl, and R 2 is:n n nwhere R 5 is selected from the group consisting of hydrogen and C 1 to C 4 alkyl, orn n nwhere R 6 , R 7 and R 8 are independently hydrogen or C 1 to C 4 alkyl; or the esters or pharmacologically acceptable salts thereof. The compounds and or their metabolites can be used to treat or prevent various diseases, particularly inflammatory conditions of the GI tract.

专利号:US-9439423-B2
优先权日:2007-10-29
标 题 :Antiparasitic agent for fish and method of controlling proliferation of fish parasites
发明人：KAWANO FUMI; HIRAZAWA NORITAKA
权利人:KAWANO FUMI; HIRAZAWA NORITAKA; NIPPON SUISAN KAISHA LTD
摘要:An antiparasitic agent for fish includes an inhibitor of folate synthesis and/or an inhibitor of folate activation as the active substance(s). A combination preparation composed of an inhibitor of folate synthesis and an inhibitor of folate activation is disclosed. Sulfonamide is disclosed as suitable for the inhibitor of folate synthesis. A dihydrofolate reductase inhibitor, a folate antagonist are disclosed as suitable inhibitors of folate activation. The antiparasitic agent is able to exterminate fish parasites via oral administration. It is effective against fish parasites belonging to the ciliate group.

专利号:US-6858434-B1
优先权日:1999-10-06
标 题:Method for synthesis, separation and screening of a plurality of compounds in the same bulk of a stationary phase
发明人：WILLIAMS LORENZO
权利人:SINVENT AS
摘要:A method for sequentially performing a synthesis, separation and screening of chemical entities, especially a combinatorial library, is described. The method utilises a bulk of a stationary phase (e.g. silica gel, aluminium oxide, cellulose, etc. for example arranged on a backing) for the performance of the synthesis, separation and screening. The technique described enables a rapid route from synthesis to the testing of chemical compounds. Screening can be performed without need for reaction work-up. Preferred screening methods are those used to determine the biological activity of the compounds.