CAS: 42348-86-7; 5-Chloro-1-Indanone

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Endo-Dicyclopentadien-1,8-Dion置于氯体系中,用 四氯化碳 作为反应溶剂,化学反应生成 5-氯-1-茚酮
参考文献:Hafner,K.; Goliasch,K.,Chemische Berichte,1961,Vol. 94,P. 2909-2921
标题:Hafner,K.; Goliasch,K.,Chemische Berichte,1961,Vol. 94,P. 2909-2921

专利信息

专利号:US-12006301-B1
优先权日:2021-05-13
标题 :And synthesis of dual 5-HT1A and 5-HT7 receptor ligands
发明人：ABLORDEPPEY SETH Y
权利人:FLORIDA A&M UNIV
摘要:Novel dual 5-HT1A and 5-HT7 receptor ligands and methods of using the novel ligands to treat a neurological disorder are presented.

专利号:US-11639336-B2
优先权日:2018-06-08
标 题:Preparation method for S-indoxacarb
发明人：BO LEIFANG; CHENG DAOQUAN; LIU JIANCHENG; FENG PEILIANG; LIU HUAMIN; WANG ZHONGYANG
权利人:SHANDONG JINGBO AGROCHEMICALS TECH CO LTD
摘要:A catalyst and a method for preparing S-indoxacarb using the catalyst. The catalyst is prepared using 3-tert-butyl-5-(chloromethyl)salicylaldehyde and cyclohexanediamine as raw materials, where an original quinine catalyst such as cinchonine is replaced with the catalyst for application in the asymmetric synthesis of tert-butyl hydroperoxide and 5-chloro-2-methoxycarbonyl-1-indanone ester, greatly improving selection in the asymmetric synthesis process, with the S-enantiomer content increasing from 75% to over 98%, achieving the recycling of a high-efficiency chiral catalyst, and greatly reducing production costs. The synthesis process of the catalyst is simple and is favorable for industrialization, and lays good foundations for the production of high-quality indoxacarb.

专利号:WO-2023122754-A1
优先权日:2021-12-23
标 题 :Processes and intermediates for preparing gb13, gb22 and himgaline
发明人：LANDWEHR ELEANOR; SHENVI RYAN; BAKER MEGHAN; OGUMA TAKUYA
权利人:SCRIPPS RESEARCH INST
摘要:Provided herein are processes for the streamlined synthesis of Galbulimima alkaloids, such as himbadine, isolated from Galbulimima belgraveana and G. baccatta, trees endemic to the rainforests of Northern Australia and Papua New Guinea, as well as analogs thereof, such as GB13, GB16, GB22, and himgaline, and further including intermediates useful in the synthesis of these and related compounds.

专利号:US-9309165-B2
优先权日:2012-12-19
标 题 :6-chloro-3-(phenyl-d5)-inden-1-one and use thereof
发明人：JACOBSEN MIKKEL FOG; BRANDES SEBASTIAN
权利人:LUNDBECK & CO AS H
摘要:The present invention discloses the compound 6-chloro-3-(phenyl-d 5 )-inden-1-one (I) and routes of synthesis to obtain (I). In a further aspect the present invention discloses the use of (I) for the synthesis of (S)-6-chloro-3-(phenyl-d 5 )-indan-1-one.

专利号:US-6316437-B1
优先权日:1999-09-30
标题:Spirohydantoin compounds and uses thereof
发明人：HOFFMAN JACOB M
权利人:MERCK & CO INC
摘要:Spirohydantoin compounds and their pharmaceutically acceptable salts are disclosed. The synthesis of these compounds and their use as alpha 1a adrenergic receptor antagonists is also described. One application of these compounds is in the treatment of benign prostatic hyperplasia. These compounds are typically selective in their ability to relax smooth muscle tissue enriched in the alpha 1a receptor subtype without at the same time inducing hypotension. One such tissue is found surrounding the urethral lining. Therefore, one utility of the instant compounds is to provide acute relief to males suffering from benign prostatic hyperplasia, by permitting less hindered urine flow. Another utility of the instant compounds is provided by combination with a human 5-alpha reductase inhibitory compound, such that both acute and chronic relief from the effects of benign prostatic hyperplasia can be achieved.

专利号:US-2023002426-A1
优先权日:2019-11-15
标题 :Chiral synthesis of a tertiary alcohol