CAS: 434-76-4; 2-Amino-6-Fluorobenzoic Acid

上下游产品

CAS号77326-36-4 2-氨基-6-氟苯腈 | CAS号1194-65-6 2,6-二氯苯腈 | CAS号1897-52-5 2,6-二氟苯腈 | CAS号652-39-1 3-氟邻苯二甲酸酐 | CAS号372-19-0 3-氟苯胺 | CAS号436-72-6 5-氟喹唑啉-4(1H)-酮 | CAS号192570-33-5 5-氟喹唑啉-2,4(1H,3H)-二酮 | CAS号78755-94-9 6-氟靛红酸酐 | CAS号86505-94-4 2-氨基-6-氟苯甲酸甲酯 | CAS号825-22-9 2-氨基-3-氟苯甲酸 | CAS号70413-94-4 5-fluoro-2-meth... | CAS号869937-08-6 1-(2-氨基-6-氟苯基)乙酮 | CAS号78755-95-0 6-fluoro-4-meth...

2-氨基-6-氟苯腈置于sodium Hydroxide体系中,用 水 作为反应溶剂,化学反应 12.0H,以90%的收率获得产物2-氨基-6-氟苯甲酸
参考文献:含取代的喹唑啉-2,4-(1 H,3 H)-二酮的寡脱氧核苷酸的三链体稳定性
标题:含取代的喹唑啉-2,4-(1 H,3 H)-二酮的寡脱氧核苷酸的三链体稳定性
摘要:通过形成hoogsteen氢键,可以在双链核酸和第三链之间观测到三重螺旋结构.我们在此报告了在ta ∗ T三联体中使用喹唑啉-2,4-二酮衍生物替代胸腺嘧啶.描述了喹唑啉-2,4-二酮,5-氟和6-硝基取代的喹唑啉环的一氯衍生物的合成和表征.通过热变性研究达到了各种修饰的碱基促进三链体形成的能力.
DOI:10.1016/s0040-4020(97)00564-4

专利信息

专利号:US-9567337-B2
优先权日:2013-12-20
标题 :Process methods for phosphatidylinositol 3-kinase inhibitors
发明人：BREMNER STACY; EVARTS JERRY; SUJINO KEIKO; TRAN DUONG; VIZITIU DRAGOS
权利人:GILEAD CALISTOGA LLC
摘要:A process for the synthesis of quinazolinone containing compounds which may be useful for the treatment of cancer, is hereby disclosed. In addition, compound intermediates relating to these processes are also disclosed.

专利号:US-2015315143-A1
优先权日:2014-05-01
标题 :N-Heterocyclic Carbene-Catalyzed Synthesis of 2-Aryl Indoles

专利号:US-9527812-B2
优先权日:2014-05-01
标题 :N-heterocyclic carbene-catalyzed synthesis of 2-aryl indoles
发明人：SCHEIDT KARL A; HOVEY JR MICHAEL TODD; CHECK CHRISTOPHER
权利人:UNIV NORTHWESTERN
摘要:Transition metal-free catalytic methods for access to 2-arylindole compounds.

专利号:CN-115010671-A
优先权日:2022-07-20
标题:One-step synthesis method of 2-substituted quinazolinone

专利号:US-9133224-B2
优先权日:2010-11-29
标 题:Macrocyclic kinase inhibitors
发明人：CREW ANDREW P; DONG HANQING; FERRARO CATERINA; SHERMAN DAN; SIU KAM W
权利人:CREW ANDREW P; DONG HANQING; FERRARO CATERINA; SHERMAN DAN; SIU KAM W; OSI PHARMACEUTICALS LLC
摘要:Compounds of Formula (I): wherein variables are defined herein, and pharmaceutically acceptable salts, synthesis, intermediates, formulations, and methods of disease treatment therewith, including cancers for which FAK inhibition is beneficial.

专利号:CN-115010671-B
优先权日:2022-07-20
标 题:One-step synthesis method of 2-substituted quinazolinone