CAS: 16874-12-7; H-Tyr-Otbu

相似化合物

87553-74-0 18938-60-8 16881-33-7

上下游产品

CAS号16881-33-7 CBZ-L-酪氨酸叔丁酯 | CAS号1164-16-5 N-苄氧羰基-L-酪氨酸 | CAS号540-88-5 醋酸叔丁酯 | CAS号60-18-4 L-酪氨酸 | CAS号5544-60-5 4-苄氧基溴苄 | CAS号81477-94-3 二苯亚甲基甘氨酸叔丁酯 | CAS号115-11-7 2-甲基丙烯 | CAS号60-18-4 L-酪氨酸 | CAS号52434-75-0 LHRH (1-5) (FRE... | CAS号16881-33-7 CBZ-L-酪氨酸叔丁酯

N-二苯亚甲基-甘氨酸叔丁酯置于palladium On Activated Charcoal 氢氧化钾,C2-Symmetric Chiral Quaternary Ammonium Salt,氢气,柠檬酸体系中,用 四氢呋喃,甲苯 用作溶剂,化学反应 15.0H,反应生成L-酪氨酸叔丁酯
参考文献:用于实际催化不对称合成的新型手性相转移催化剂的设计
标题:用于实际催化不对称合成的新型手性相转移催化剂的设计
摘要:衍生自商业可获得的(S)-联萘酚的1型结构刚性手性螺环铵盐已被设计为一种新型的c 2对称手性相转移催化剂,已成功地用于甘氨酸叔丁酯的高效催化对映选择性烷基化schiff碱在温和的相转移条件下可提供具有出色对映选择性的α-烷基-α-氨基酸和α,α-二烷基-α-氨基酸.这些铵盐也已用于原位生成手性季铵氟化物.
Doi:10.1016/s0022-1139(01)00472-9

专利信息

专利号:US-8268936-B2
优先权日:2005-01-04
标题:Synthesis of hybrid block copolymers and uses thereof
发明人：BREITENKAMP KURT; SILL KEVIN N
权利人:BREITENKAMP KURT; SILL KEVIN N; INTEZYNE TECHNOLOGIES INC
摘要:The present invention relates to the field of polymer chemistry and more particularly to multiblock copolymers and methods of preparing the same.

专利号:US-2012196989-A1
优先权日:2005-02-11
标题:Synthesis of homopolymers and block copolymers
发明人：BREITENKAMP KURT; SILL KEVIN N
权利人:BREITENKAMP KURT; SILL KEVIN N; INTEZYNE TECHNOLOGIES INC
摘要:The present invention relates to the field of polymer chemistry and more particularly to homopolymers and block copolymers and methods of preparing the same.

专利号:US-8030496-B2
优先权日:2005-02-17
标 题:Intermediate compound for synthesis of viridiofungin a derivative
发明人：KATO TATSUYA; KIMURA NOBUAKI; MIZUTANI AKEMI; MAKINO TOSHIHIKO; KAWASAKI KENICHI; FUKUDA HIROSHI; KOMIYAMA SUSUMU; TSUKUDA TAKUO
权利人:CHUGAI PHARMACEUTICAL CO LTD
摘要:A method whereby a compound having HCV replication inhibitory activity and desired optical activity can be synthesized selectively and at high yield in a small number of steps by using a compound having a specific chiral auxiliary as a starting compound is provided. n A compound represented by the formula (1-8): n n n n n n n n n n n n wherein Y represents a group represented by the following formula: n n n n n n n n n n n n n n n n Q represents a protected carbonyl group; D represents —(CH 2 ) m —R′, etc.; and n represents an integer of 0 to 10.

专利号:US-5688992-A
优先权日:1995-03-31
标题 :O-malonyltryrosyl compounds, O-malonyltryrosyl compound-containing peptides, and use thereof
发明人：BURKE JR TERRENCE R; YE BIN; AKAMATSU MIKI; KOLE HEMANTA K; YAN XINJIAN; ROLLER PETER R
权利人:US HEALTH
摘要:The present invention relates to non-phosphorus containing O-malonyltryrosyl compounds, derivatives thereof, uses of the O-malonyltryrosyl compounds in the synthesis of peptides, and O-malonyltryrosyl compound-containing peptides. The O-malonyltyrosyl malonyltyrosyl compounds and O-malonyltryrosyl compound-containing peptides of the present invention are uniquely stable to phosphotases, capable of crossing cell membranes, suitable for application to peptide synthesis of O-malonyltryrosyl compound-containing peptides, and amenable to prodrag defivatization for delivery into cells. The present invention also provides for O-malonyltryrosyl compound-containing peptides which exhibit inhibitory potency against binding interactions of receptor domains with phosphotyrosyl-containing peptide ligands.

专利号:WO-2019241903-A1
优先权日:2018-06-19
标 题 :Synthetic method of bivalirundin
发明人：BONAVENTURA IVAN DI; HE RUNZE
权利人:SHANGHAI SPACE PEPTIDES PHARMACEUTICAL CO LTD
摘要:The Active Pharmaceutical Ingredient (API), Bivalirudin, is a 20 amino acid peptide containing one basic and 5 amino acid residues. With a chemical formula of C98H138N24O33 and a molecular weight of 2180.3 g/mol. Bivalirudin is also known as Angiomax. It is a direct thrombin inhibitor indicated for use as an anticoagulant. It provides a method for synthesizing bivalirudin and in particular to the synthetic method of bivalirudin by solid phase peptide synthesis using Fmoc-Leu-Wang resin as a carrier. The method has the advantages of high yield, less by-product and simple separation and purification, and it's time gaining than the prior art, and is suitable for pilot and industrial production.

专利号:US-2006172914-A1
优先权日:2005-01-04
标题:Synthesis of hybrid block copolymers and uses thereof