专利号:US-4234744-A 优先权日:1978-12-18 标 题 :Process for the production of aminoacid hydrochlorides/or diaminoacid dihydrochlorides 发明人:EFFENBERGER FRANZ; DRAUZ KARLHEINZ 权利人:DEGUSSA 摘要:Aminoacid hydrochlorides or diaminoacid dihydrochlorides are produced by first reacting a halocarboxylic acid ester with an alkali metal cyanate in the presence of an alcohol to form the corresponding mono- or diurethane and then saponifying this to the corresponding mono- or dihydrochloride. The new process is relatively versatile in its use and above all opens up an elegant synthesis route for lysine.
专利号:CN-104478779-A 优先权日:2014-11-24 标题 :A new method for the synthesis of nootropic drug piracetam
专利号:WO-2024060271-A1 优先权日:2022-09-23 标 题 :Characteristic impurity in empagliflozin bulk drug or preparation and use thereof 发明人:WANG HAIBO; MEI GUANGYAO; JIN HUI; XU CHENLI; YU LIXIA; XIAO YANG; Bai Xugang; WANG ZIKANG; Chen Antu; PAN YINGWEI; MENG HAIPING; XU XIAOYANG; ZHANG FENG; XI JUNQING; WU YUJUAN 权利人:ZHEJIANG HONGYUAN PHARMACEUTICAL CO LTD 摘要:Provided are a characteristic impurity in an empagliflozin bulk drug or preparation and use thereof, and further provided are a detection method, a synthesis method, in-vitro pharmacological activity and in-vitro toxicity of the impurity. The present invention provides an important basis for quality control of an empagliflozin bulk drug or preparation, and is of great significance to quality control of the empagliflozin bulk drug or preparation.
专利号:CN-217068857-U 优先权日:2021-12-27 标 题:A kind of synthesis equipment of piracetam
专利号:CN-113480521-A 优先权日:2021-07-12 标题:A kind of bepotastine besylate total synthesis method
专利号:CN-113480521-B 优先权日:2021-07-12 标题 :A kind of bepotastine besylate total synthesis method