CAS: 345-18-6; 5-Chloro-2-Fluoronitrobenzene

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CAS号89-61-2 2,5-二氯硝基苯 | CAS号610-40-2 3,4-二硝基氯苯 | CAS号371-40-4 4-氟苯胺 | CAS号352-33-0 对氯氟苯 | CAS号364-76-1 4-氟-3-硝基苯胺 | CAS号4548-56-5 4-氯-2-硝基二苯硫醚 | CAS号147124-32-1 2-(4-氯-2-硝基苯基)丙二酸二甲酯 | CAS号4533-96-4 4-氯-2-硝基苯磺酰氯 | CAS号193698-88-3 DIETHYL (4-CHLO... | CAS号89-63-4 邻硝基对氯苯胺 | CAS号89-21-4 4-氯-2-硝基苯甲醚 | CAS号89-64-5 4-氯-2-硝基苯酚 | CAS号62476-15-7 5-氯-2-(乙胺基)苯胺 | CAS号696-02-6 4-氯-1,2-二氟苯 | CAS号133117-00-7 2-chloro-1-(2-c...

2,5-二氯硝基苯置于potassium Fluoride体系中,用 二甲基亚砜,苯 作为反应溶剂,化学反应生成 5-氯-2-氟硝基苯
参考文献:Hydroxylamine Derivative Of 5-Nitro-8-Hydroxy Quinoline
标题:Hydroxylamine Derivative Of 5-Nitro-8-Hydroxy Quinoline
摘要:该专利涉及一种新型羟胺衍生物,其化学式为ar--Onh.Sub.2,其中ar选自包括单环和多环芳烃和杂环芳烃的群体,这些芳烃和杂环芳烃可以选择性地取代至少一个--Oh,卤素,--No.Sub.2,--Cn,##str1##--R.Sub.7,--Or.Sub.8,##str2##--So.Sub.2 R.Sub.12,--So.Sub.3 R.Sub.13,--Coor.Sub.14,6到14个碳原子的芳基,--Or.Sub.16,--Ch.Sub.2--Cn和--Ch.Sub.2 So.Sub.2--R.Sub.15的群体中的至少一个成员,R.Sub.1,R.Sub.2,R.Sub.3,R.Sub.4,R.Sub.5和r.Sub.6分别选自氢和1到8个碳原子的烷基的群体,R.Sub.7和r.Sub.8可以选择性地为1到8个碳原子的不饱和烷基,该烷基可以选择性地取代至少一个卤素和氰基,R.Sub.9,R.Sub.10,R.Sub.11,R.Sub.12和r.Sub.13为1到8个碳原子的烷基,Z选自包括氢,可选择性不饱和的1到8个碳原子的烷基和2到18个碳原子的有机羧酸酰基的群体,R.Sub.14选自包括氢和1到8个碳原子的烷基的群体,R.Sub.15选自包括1到8个碳原子的烷基和6到14个碳原子的芳基的群体,该芳基可以选择性地取代1到8个碳原子的烷基,R.Sub.16为6到14个碳原子的芳基,可以选择性地取代包括1到8个碳原子的烷基,卤素和--No.Sub.2的群体的成员,Ar的取代基能够形成含有至少一个氧,氮和硫的杂原子的环,并且其非毒性农业可接受的酸盐,但ar不能为苯基,也不能为苯基在2,3或4位上带有一个甲基,2-或4-位上带有一个硝基,3-或4-位上带有一个氯,4-位上带有一个溴或4-位上带有一个--Cf.Sub.3,也不能为2,4-二硝基苯基,2-硝基-4-三氟甲基苯基,2,6-二硝基苯基,2,4,6-三硝基苯基或2,4-二硝基-6-三氟甲基苯基.这种羟胺衍生物可用于促进植物生长和增加作物产量,以及其制备方法.

专利信息

专利号:US-2023364251-A1
优先权日:2020-08-06
标 题:Methods for the synthesis of protein-drug conjugates
发明人：BORCHARDT ALLEN; HUGHES ROBERT MICHAEL
权利人:CIDARA THERAPEUTICS INC
摘要:The present invention relates to intermediates and methods for synthesizing protein-drug conjugates that can be used for the treatment of diseases and related conditions.

专利号:US-5646085-A
优先权日:1991-10-04
标题:Material based on tungsten carbide(s), catalyst and process useful for the hydrogenation of an aromatic nitro or nitroso derivative employing this catalyst
发明人：JACQUOT ROLAND; MERCIER CLAUDE
权利人:RHONE POULENC CHIMIE
摘要:The present invention relates to a process and a catalyst for hydrogenation of aromatic nitro or nitroso (nitrosated) compounds. The process, useful in hydrogenation, especially in the liquid phase, of compounds, nitroaromatic ones in particular, is defined in that the said compound is hydrogenated in the presence of tungsten carbide, the partial pressure of hydrogen being at least equal to two atmospheres (2x105 pascals). The process also has application to organic synthesis.

专利号:TW-202220698-A
优先权日:2020-08-06
标题:Methods for the synthesis of protein-drug conjugates

专利号:EP-4192512-A1
优先权日:2020-08-06
标题 :Methods for the synthesis of protein-drug conjugates

专利号:CN-108997177-A
优先权日:2018-09-04
标题 :A kind of microwave-promoted method for the synthesis of N-benzenesulfonylnitroaniline compounds

专利号:WO-2022032175-A1
优先权日:2020-08-06
标题 :Methods for the synthesis of protein-drug conjugates