相似化合物
62482-26-2 287176-62-9 4366-88-5欧盟法规
ECHA物质C&L通报上下游产品
4-carboxyquinoline 1-oxide 2-hydroxyquinoline-4-carboxylic acid ethyl ester of 2-chlor°Cinchoninic acid 2-quinolone-4-carboxylic acid 2-morpholinoquinoline-4-carboxylic acid 2-(n-butyloxy)-4-quinolinecarboxylic acid 2-phenylsulfanyl-quinoline-4-carboxylic acid 2-amino-quinoline-4-carboxylic acid 合成工艺路线路线简述
- 合成目标产物 2-Chloroquinoline-4-Carboxylic Acid 主要起始原料 2-Hydroxy-4-Quinolincarboxylic Acid
- (文献来源)合成步骤主要原料 2-Hydroxy-4-Quinolincarboxylic Acid
4-Carboxyquinoline 1-Oxide置于三氯氧磷体系中,化学反应生成 2-氯喹林-4-羧酸
参考文献:Colonna; Risaliti,Bollettino Scientifico Della Facolta Di Chimica Industriale Di Bologna,1951,Vol. 9,P. 82
标题:Colonna; Risaliti,Bollettino Scientifico Della Facolta Di Chimica Industriale Di Bologna,1951,Vol. 9,P. 82
海关参考信息
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2905110000-甲醇
2912110000-甲醛
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专利信息
专利号:US-8129411-B2
优先权日:2005-12-30
标题:Organic compounds
发明人:EHARA TAKERU; GROSCHE PHILIPP; IRIE OSAMU; IWAKI YUKI; KANAZAWA TAKANORI; KAWAKAMI SHIMPEI; KONISHI KAZUHIDE; MOGI MUNETO; SUZUKI MASAKI; YOKOKAWA FUMIAKI
权利人:EHARA TAKERU; GROSCHE PHILIPP; IRIE OSAMU; IWAKI YUKI; KANAZAWA TAKANORI; KAWAKAMI SHIMPEI; KONISHI KAZUHIDE; MOGI MUNETO; SUZUKI MASAKI; YOKOKAWA FUMIAKI; NOVARTIS AG
摘要:The invention relates to 3,5-substituted piperidine compounds, these compounds for use in the diagnostic and therapeutic treatment of a warm-blooded animal, especially for the treatment of a disease (=disorder) that depends on activity of renin; the use of a compound of that class for the preparation of a pharmaceutical formulation for the treatment of a disease that depends on activity of renin; the use of a compound of that class in the treatment of a disease that depends on activity of renin; pharmaceutical formulations comprising a 3,5-substituted piperidine compound, and/or a method of treatment comprising administering a 3,5-substituted piperidine compound, a method for the manufacture of a 3,5-substituted piperidine compound, and novel intermediates and partial steps for its synthesis. n The compounds have the formula I′ n nwherein R1, R2, T, R3 and R4 are as defined in the specification.