CAS: 831-29-8; 1-(2,4-Dimethoxyphenyl)Propan-2-One

该化合物是一种多用途有机化合物,其特征是其角氧代苯丙酮结构.这一中间体在合成化学中特别有用,因为它作为酮的活性以及甲氧基组的电子施食效应,这增强了其在电除阴替代和凝聚反应中的效用.其定义明确的分子框架使它在合成药物,农用化学品和精美化学品方面成为首选前体.该复合体在标准条件下的稳定性和与一系列试剂的兼容性进一步有助于其在多步有机转化中的应用. 高纯度可以满足严格的研究和工业要求.

英文名称1-(2,4-Dimethoxyphenyl)Propan-2-One
中文名称2,4-二甲氧基苯基丙酮
IUPAC名称1-(2,4-dimethoxyphenyl)propan-2-one
其它别名(2,4-Dimethoxyphenyl)Acetone; 2,4-Methoxyphenylacetone; 1-(2,4-Dimethoxyphenyl)Propan-2-One; 1-(2,4-Dimethoxyphenyl)-2-Propanone; 2-Propanone, 1-(2,4-Dimethoxyphenyl)-; (2,4-Dimethoxyphenyl)Acetone Usp/ep/bp
CAS编号831-29-8
MFCD编号:MFCD00192065
分子式:C11H14O3
分子量:194.23
产品CID: 1820440
产品分类香精与香料 → 合成香料 → 酮类香料

相似结构搜索
InChIKey: LDUYRQGNBYKUAG-UHFFFAOYSA-N
InChI=1S/C11H14O3/c1-8(12)6-9-4-5-10(13-2)7-11(9)14-3/h4-5,7H,6H2,1-3H3…
计算化学: 氢键受体数3.0氢键供体数0.0可旋转键数4.0

MSDS等安全信息

WGK Germany3

上下游产品

1-(2,4-Dimethoxy-phenyl)-propan-2-one O-methyl-oxime 1-(2,4-Dimethoxyphenyl)-2-nitropropen 1-Bromo-2,4-dimethoxybenzene acetone 1-(2,4-dimethoxyphenyl)propan-2-ol 2,4-dimethoxyamphetamine 2,3,5,6-tetraphenylpyrazine H-pyran-3-carbonitrile5-(2,4-dimethoxy-phenyl)-6-methyl-4-methylsulfanyl-2-oxo-2H-pyran-3-carbonitrile

合成工艺路线路线简述

151-10-0 + 4749-28-4 = 831-29-8
反应条件:1.1 Reagents: Trifluoromethanesulfonic Acid Solvents: Dichloromethane1.2 Reagents: Methanol1.3 Reagents: Water
标题:Novel Electrophilic Species Equivalent To α-Keto Cations. Reactions Of 0,0-Diprotonated Nitro Olefins With Benzenes Yield Arylmethyl Ketones
作者:Okabe,Kazuaki; Et Al
参考文献:Journal Of Organic Chemistry 日期:1989 卷标:54(4) 页码:733-4]

17736-45-7 = 831-29-8
反应条件:1.1 Reagents: Polyethylene Glycol Mono(Tert-Octylphenyl) Ether Catalysts: 2-Iodo-5-Methylbenzenesulfonic Acid Solvents: Isopropanol,Tert-Butyl Methyl Ether,Water; 5 Min,Rt; 30 Min,Rt -> 0 °C1.2 Reagents: Potassium Peroxymonosulfate Sulfate (2Khso5.Khso4.K2So4); 1 H,0 °C; 0 °C -> 20 °C; 30 H,20 °C; 105 Min,20 °C; 20 °C -> 5 °C; 10 Min1.3 Reagents: Sodium Sulfite Solvents: Tert-Butyl Methyl Ether,Water; Rt1.4 Reagents: Sodium Hydroxide Solvents: Water; Ph 9 - 101.5 Reagents: Sodium Bisulfite Solvents: Isopropanol,Water; 30 H,Rt1.6 Reagents: Hydrochloric Acid Solvents: Tert-Butyl Methyl Ether,Water; 1 - 1.5 H,Rt
标题:Catalytic Oxidative 1,2-Shift In 1,1'-Disubstituted Olefins Using Arene(Iodo)Sulfonic Acid As The Precatalyst And Oxone As The Oxidant
作者:Purohit,Vikram C.; Et Al
参考文献:Organic Letters 日期:2013 卷标:15(7) 页码:1650-1653]

= 831-29-8
反应条件:1.1 Reagents: Selenium Dioxide Catalysts: Sulfuric Acid Solvents: Dichloromethane; 10 H,10 °C2.1 Catalysts: 9,10-Dimethoxyanthracene Solvents: Acetonitrile; 20 - 25 H
标题:Transition-Metal-Free Photoredox Intermolecular α-Arylation Of Ketones
作者:Pandey,Ganesh; Et Al
参考文献:Organic Chemistry Frontiers 日期:2018 卷标:5(17) 页码:2610-2614]

7311-34-4 = 831-29-8
反应条件:1.1 Catalysts: Ammonium Acetate2.1 Reagents: Acetic Acid,Iron
标题:Synthesis Of Iodine-122- And Iodine-125-Labeled Meta-Dimethoxy-N,N-Dimethyliodophenylisopropylamines
作者:Mathis,Chester A.; Et Al
参考文献:Journal Of Labelled Compounds And Radiopharmaceuticals 日期:1986 卷标:23(2) 页码:115-25]

61759-13-5 + 151-10-0 = 831-29-8
反应条件:1.1 Catalysts: 9,10-Dimethoxyanthracene Solvents: Acetonitrile; 20 - 25 H
标题:Transition-Metal-Free Photoredox Intermolecular α-Arylation Of Ketones
作者:Pandey,Ganesh; Et Al
参考文献:Organic Chemistry Frontiers 日期:2018 卷标:5(17) 页码:2610-2614]

15804-78-1 = 831-29-8
反应条件:1.1 Reagents: Acetic Acid,Iron
标题:Synthesis Of Iodine-122- And Iodine-125-Labeled Meta-Dimethoxy-N,N-Dimethyliodophenylisopropylamines
作者:Mathis,Chester A.; Et Al
参考文献:Journal Of Labelled Compounds And Radiopharmaceuticals 日期:1986 卷标:23(2) 页码:115-25]

25088-58-8 + 17715-69-4 = 831-29-8
反应条件:1.1 Catalysts: Ammonium Nitrate Solvents: Diethyl Ether
标题:Synthesis Of Arylacetones By The Srn 1 Arylation Of Acetone Enolate Ion
作者:Bunnett,Joseph F.; Et Al
参考文献:Chemical & Pharmaceutical Bulletin 日期:1975 卷标:23(11) 页码:2620-8]

2065-66-9 + 829-20-9 = 831-29-8
反应条件:1.1 Solvents: Tetrahydrofuran; 15 Min,Rt1.2 Reagents: Potassium Tert-Butoxide Solvents: Tetrahydrofuran; 10 Min,40 °C; 75 Min,40 °C1.3 Solvents: Heptane; 30 Min,23 °C2.1 Reagents: Polyethylene Glycol Mono(Tert-Octylphenyl) Ether Catalysts: 2-Iodo-5-Methylbenzenesulfonic Acid Solvents: Isopropanol,Tert-Butyl Methyl Ether,Water; 5 Min,Rt; 30 Min,Rt -> 0 °C2.2 Reagents: Potassium Peroxymonosulfate Sulfate (2Khso5.Khso4.K2So4); 1 H,0 °C; 0 °C -> 20 °C; 30 H,20 °C; 105 Min,20 °C; 20 °C -> 5 °C; 10 Min2.3 Reagents: Sodium Sulfite Solvents: Tert-Butyl Methyl Ether,Water; Rt2.4 Reagents: Sodium Hydroxide Solvents: Water; Ph 9 - 102.5 Reagents: Sodium Bisulfite Solvents: Isopropanol,Water; 30 H,Rt2.6 Reagents: Hydrochloric Acid Solvents: Tert-Butyl Methyl Ether,Water; 1 - 1.5 H,Rt
标题:Catalytic Oxidative 1,2-Shift In 1,1'-Disubstituted Olefins Using Arene(Iodo)Sulfonic Acid As The Precatalyst And Oxone As The Oxidant
作者:Purohit,Vikram C.; Et Al
参考文献:Organic Letters 日期:2013 卷标:15(7) 页码:1650-1653

2,4-Dimethoxybenzophenone置于2-碘-5-甲基苯磺酸体系中,用四氢呋喃,甲基叔丁基醚,水,异丙醇作为反应溶剂,化学反应 4.42H,反应生成 2,4-二甲氧基苯基丙酮
参考文献:以芳烃(碘)磺酸为前驱体,以丙酮为氧化剂,催化1,1'-双取代烯烃中的1,2-氧化转变
标题:以芳烃(碘)磺酸为前驱体,以丙酮为氧化剂,催化1,1'-双取代烯烃中的1,2-氧化转变
摘要:描述了一种有效的催化高价碘介导的1,1'-二取代烯烃的氧化1,2-转变.该方法学提供了具有给电子取代基的均苄基酮的简明途径.在环状体系的情况下,这种转化导致环扩环的β-苯并环烷酮,这对于进一步完善是有用的.
DOI:10.1021/ol400432X