专利号:WO-2025056767-A1 优先权日:2023-09-15 标题 :Process for the preparation of enantiomerically enriched aliphatic amines 发明人:BOU HAMDAN FARHAN; GODINEAU EDOUARD; SMEJKAL TOMAS; DUMEUNIER RAPHAEL; BOUSSEMGHOUNE MOHAMED ABDELOUAHAB; BLUM MATHIAS 权利人:SYNGENTA CROP PROTECTION AG 摘要:The present invention relates to a process for the preparation of enantiomerically enriched cyclobutylamines of formula (I) from α-tertiary cyclobutanones and reacting said enantiomerically enriched cyclobutylamines to enantiomerically enriched cyclobutylamides. Such compounds are useful intermediates in the synthesis of microbiocidal thiazole compounds.
专利号:CN-101456853-A 优先权日:2009-01-05 标题:Synthesis of a new series of biomimetic compounds 7-alkoxy-8-(3,3'-disubstituted propyl)benzopyran-2-ones and their application as pesticides
专利号:CN-101456852-A 优先权日:2008-12-22 标 题:A new method for the synthesis of osthole derivatives
专利号:WO-2021038306-A1 优先权日:2019-08-28 标 题 :Selenophenochromene phosphonic acids, preparation and use as antiproliferative agents 发明人:ARSENJANS PAVELS; DOMRACEVA ILONA; PAEGLE EDGARS 权利人:LATVIAN INST ORGANIC SYNTHESIS 摘要:The present invention relates to a novel selenophenochromene phosphonic acids as antiproliferative agents, as well as methods of their manufacturing and use in different pharmaceutical compositions for the treatment or prevention of various diseases and disorders by administration of such substances.
专利号:CN-116832060-A 优先权日:2023-08-18 标题 :A kind of Cnidium monnieri extract-mediated synthesis of nano-silver material and its preparation method and application
专利号:US-11285169-B2 优先权日:2013-03-13 标题 :Methods for modulating chemotherapeutic cytotoxicity 发明人:ROBERTS DAVID D; SOTO PANTOJA DAVID R 权利人:US HEALTH 摘要:Methods of reducing cytotoxicity of a chemotherapeutic agent to non-cancer cells by administering to a subject with cancer an effective amount of an agent that inhibits CD47 signaling and a DNA damaging agent, such as an anthracycline, topoisomerase inhibitor, or nucleotide synthesis inhibitor, are provided. Example disclosed methods reduce cardiotoxicity. In one example, the methods include administering to a subject with cancer an effective amount of a CD47 antisense morpholino oligonucleotide and an anthracycline such as doxorubicin. Methods of increasing cytotoxicity of a chemotherapeutic agent in cancer cells by administering to a subject with a tumor an effective amount of an agent that inhibits CD47 signaling and a DNA damaging agent such as an anthracycline, topoisomerase inhibitor, or nucleotide synthesis inhibitor, are also provided. In some embodiments, the inhibitor of CD47 signaling is administered to the subject before, during, or after the administration of the DNA damaging agent.
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合成参考文献
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