CAS: 548-76-5; 5,7-Dihydroxy-3-(3-Hydroxy-4,5-Dimethoxyphenyl)-6-Methoxy-4H-Chromen-4-One
该化合物是主要存在于各种植物物种中,特别是原生类伊里斯的天然浮质化合物,其特点是多苯基结构,有助于其抗氧化特性;伊利根因展示了一系列生物活动,包括抗炎,抗微生物和潜在的抗癌影响,使其对药理学研究感兴趣;该化合物通常溶解有机溶剂,在水中溶解性有限,许多植物类都常见;其分子结构包括多种氢氧基组,加强了其再活性和与生物系统的相互作用;正在探索伊利根因的潜在治疗应用,特别是在传统医学方面,因为传统医学已经用于健康利益;然而,必须进一步研究,以充分了解其在临床环境中的行动和功效机制;与许多天然化合物一样,提取和净化过程会影响其在研究和治疗应用中的可得性和效力.
- 英文名称5,7-Dihydroxy-3-(3-Hydroxy-4,5-Dimethoxyphenyl)-6-Methoxy-4H-Chromen-4-One
- 中文名称野鸢尾黄素
- IUPAC名称5,7-dihydroxy-3-(3-hydroxy-4,5-dimethoxyphenyl)-6-methoxy-4H-chromen-4-one
- 其它别名5,7-Dihydroxy-3-(3-Hydroxy-4,5-Dimethoxyphenyl)-6-Methoxy-4-Benzopyrone; 5,7-Dihydroxy-3-(3-Hydroxy-4,5-Dimethoxyphenyl)-6-Me
- CAS编号548-76-5
- MFCD编号:MFCD00597047
- EINECS号:208-958-3
- FDA UNII编号:6O4NX37350
- 分子式:C18H16O8
- 分子量:360.32
- 产品CID: 2498938
- 产品分类生物化工 → 提取物
物理性质
- 熔点189-192 °C
- 沸点646.1 °C at 760mmHg
- 闪点237.7 °C
- 密度1.461g/cm3
- pKa:6.36±0.20(预测)
- PSA:118.59
- LogP:2.6026
- 折射率1.649
- 蒸汽压2.71E-17 mmHg at 25 °C
- 溶解性Soluble In Ethanol And Methan
- 外观形态白色粉末
- 储存条件2-8°C
- 产品应用该化合物用作内容确定,识别和药理实验;通过具体封锁A-C环外DOLIMA A(EDA)的Α-9-Β1和Α4-Β-1内装订点,抑制转移,以显示抗癌活动;通过更新对亲食性分子的管制,使气态癌细胞中气态诱发的气态疾病敏感化;抑制EPITHERIAL-MESENCHYMAL过渡.
MSDS等安全信息
上下游产品
CAS号64-18-6 甲酸 | CAS号487-71-8 1,3,5-三羟基2-甲氧基苯合成工艺路线路线简述
Alkaline Earth Salt Of/the/ Methylsulfuric Acid置于乙醇,硫酸,水体系中,化学反应生成 野鸢尾黄素
参考文献:De Laire; Tiemann,Chemische Berichte,1893,Vol. 26,P. 2019
标题:De Laire; Tiemann,Chemische Berichte,1893,Vol. 26,P. 2019
海关参考信息
- 2905110000-甲醇
2907210001-间苯二酚
2907221000-对苯二酚
2908199090-其他酚的卤化衍生物 - 💡 提示：海关信息按照顺序优先匹配，如需确认的海关信息，请参考相关资料。
- 详情请参考：📖 海关编码查询和海关进出口税则
专利信息
专利号:WO-2006053688-A1
优先权日:2004-11-17
标 题:Cosmetic and dermatological preparations for the treatment of mature skin
发明人：DOERING THOMAS
权利人:HENKEL KGAA; DOERING THOMAS
摘要:The invention relates to topical cosmetic or dermatological compositions for the treatment of mature or intrinsically or extrinsically aged skin, in particular, for anti-wrinkle treatment, containing a combination of at least two selected peptides in a suitable cosmetic or dermatological vehicle, which have an effect at differing points of the process of collagen and/or fibronectin synthesis.
专利号:WO-2006042625-A2
优先权日:2004-10-15
标 题 :Compositions with inhibitors of the synthesis of prostaglandin and/or of leukotriene in conjunction with stimulators of the release of cutaneous neuromediators
专利号:EP-1799311-A2
优先权日:2004-10-15
标 题:Compositions with inhibitors of the synthesis of prostaglandin and/or of leukotriene in conjunction with stimulators of the release of cutaneous neuromediators
专利号:DE-102005000868-A1
优先权日:2004-10-15
标 题:Compositions with inhibitors of prostaglandin and / or leukotriene synthesis in combination with stimulants of the release of cutaneous neuromediators
专利号:CN-115612114-A
优先权日:2021-07-14
标 题:Method and application of copolymer film and its enzymatic self-assembly synthesis
专利号:CN-107652183-B
优先权日:2017-10-17
标题 :Synthesis method of tert-butyl cyclohexyl ethyl carbonate spice
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📌 第三方产品分析报告
主要参考文献
1: Guo F, Wang X, Liu X. Protective effects of irigenin against 1-methyl-4-phenylpyridinium-induced neurotoxicity through regulating the Keap1/Nrf2 pathway. Phytother Res. 2021 Mar;35(3):1585-1596. doi: 10.1002/ptr.6926. Epub 2020 Oct 29.
349:109681. doi: 10.1016/j.cbi.2021.109681. Epub 2021 Oct 1. 82(7):999-1007. doi: 10.1002/ddr.21802. Epub 2021 Feb 26.
1181:122914. doi: 10.1016/j.jchromb.2021.122914. Epub 2021 Aug 28. 496(3):998-1005. doi: 10.1016/j.bbrc.2018.01.003. Epub 2018 Jan 2.
合成参考文献
摘要:S109 | PARCEDC | List of 7074 potential endocrine disrupting compounds (EDCs) by PARC T4.2 | DOI:10.5281/zenodo.10944198
参考文献:10.1007/bf02976631
摘要:Jung SH, Lee YS, Lee S, Lim SS, Kim YS, Shin KH. Isoflavonoids from the rhizomes of Belamcanda chinensis and their effects on aldose reductase and sorbitol accumulation in streptozotocin induced diabetic rat tissues. Arch Pharm Res. 2002 Jun;25(3):306–12. doi: 10.1007/bf02976631.
参考文献:10.1016/j.lfs.2005.09.041
摘要:Ahn KS, Noh EJ, Cha KH, Kim YS, Lim SS, Shin KH, Jung SH. Inhibitory effects of Irigenin from the rhizomes of Belamcanda chinensis on nitric oxide and prostaglandin E(2) production in murine macrophage RAW 264.7 cells. Life Sci. 2006 Apr 11;78(20):2336–42. doi: 10.1016/j.lfs.2005.09.041.
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